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Article

Composite Alloplastic Biomaterial vs. Autologous Platelet-Rich Fibrin in Ridge Preservation

1
Department of Periodontology, School of Dentistry, Cientifica del Sur University, Lima 15067, Peru
2
Department of Oral Surgery and Implant Dentistry, School of Dentistry, University of Granada, 18071 Granada, Spain
3
Department of Pathology & Institute of Biopathology and Regenerative Medicine (IBIMER, CIBM), University of Granada, 18071 Granada, Spain
4
Department of Periodontology, School of Dentistry, University of Granada, 18071 Granada, Spain
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2019, 8(2), 223; https://doi.org/10.3390/jcm8020223
Received: 17 January 2019 / Revised: 5 February 2019 / Accepted: 8 February 2019 / Published: 9 February 2019
(This article belongs to the Section Stomatology)
Aim: The aim of this study was to examine the clinical and histological differences of using a combination of alloplastic beta triphasic calcium phosphate (β-TCP) and a cross-linked collagen membrane versus autologous platelet-rich fibrin (PRF-L) in ridge preservation after dental extraction. Material and methods: Fifty-one patients were included in this observational case-series study. Dental extractions were performed, after which 25 patients were grafted with β-TCP and 26 with PRF-L. After four months of healing, clinical, radiological, histomorphometric and histological evaluations were performed. Results: A significantly higher percentage of mineralized tissue was observed in samples from the PRF-L grafted areas. Cellularity was higher in PRF-L grafted areas (osteocytes in newly formed bone per mm2 = 123.25 (5.12) vs. 84.02 (26.53) for PRF-L and β-TCP, respectively, p = 0.01). However, sockets grafted with PRF-L showed a higher reduction in the bucco-lingual dimension after four months of healing (2.19 (0.80) vs. 1.16 (0.55) mm, p < 0.001), as well as a higher alteration in the final position of the mid muco-gingival junction (1.73 (1.34) vs. 0.88 (0.88) mm, p < 0.01). Conclusion: PRF-L concentrate accelerates wound healing in post-extraction sockets in terms of new mineralized tissue component. However, the use of β-TCP biomaterial appears to be superior to maintain bucco-lingual volume and the final position of the muco-gingival junction. View Full-Text
Keywords: beta triphasic calcium phosphate (β-TCP); platelet-rich fibrin (PRF-L); ridge augmentation; post-extraction socket beta triphasic calcium phosphate (β-TCP); platelet-rich fibrin (PRF-L); ridge augmentation; post-extraction socket
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MDPI and ACS Style

Mendoza-Azpur, G.; Olaechea, A.; Padial-Molina, M.; Gutiérrez-Garrido, L.; O’Valle, F.; Mesa, F.; Galindo-Moreno, P. Composite Alloplastic Biomaterial vs. Autologous Platelet-Rich Fibrin in Ridge Preservation. J. Clin. Med. 2019, 8, 223. https://doi.org/10.3390/jcm8020223

AMA Style

Mendoza-Azpur G, Olaechea A, Padial-Molina M, Gutiérrez-Garrido L, O’Valle F, Mesa F, Galindo-Moreno P. Composite Alloplastic Biomaterial vs. Autologous Platelet-Rich Fibrin in Ridge Preservation. Journal of Clinical Medicine. 2019; 8(2):223. https://doi.org/10.3390/jcm8020223

Chicago/Turabian Style

Mendoza-Azpur, Gerardo, Allinson Olaechea, Miguel Padial-Molina, Lourdes Gutiérrez-Garrido, Francisco O’Valle, Francisco Mesa, and Pablo Galindo-Moreno. 2019. "Composite Alloplastic Biomaterial vs. Autologous Platelet-Rich Fibrin in Ridge Preservation" Journal of Clinical Medicine 8, no. 2: 223. https://doi.org/10.3390/jcm8020223

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