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J. Clin. Med. 2019, 8(2), 150;

Syncope in a Working-Age Population: Recurrence Risk and Related Risk Factors

Internal Medicine, Humanitas Clinical and Research Center, Biomedical Sciences Department, Humanitas University, 20089 Rozzano, Italy
Dipartimento di Scienze Biomediche e Cliniche "L. Sacco"-Università degli Studi di Milano, 20157 Milan, Italy
Emergency Department, Ospedale di Rho, ASST Rhodense, 20017 Rho, Italy
Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy
Libin Cardiovascular Institute of Alberta, Department of Cardiac Sciences, University of Calgary, Calgary, AB T2N 4Z6, Canada
Division of Emergency Medicine, Stanford University, Stanford, CA 94305, USA
Author to whom correspondence should be addressed.
Received: 12 January 2019 / Revised: 24 January 2019 / Accepted: 28 January 2019 / Published: 29 January 2019
(This article belongs to the Section Epidemiology & Public Health)
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Syncope in a worker undertaking risky tasks may result in fatalities for the individual or for third parties. We aimed at assessing the rate of syncope recurrence and the risk factors underlying the likelihood of syncope relapse in a working-age population. A prospective cohort of all patients aged 18–65 years consecutively admitted to the Emergency Department for syncope was enrolled. Risk of syncope relapse was assessed at a six-month, 1-year, and 5-year follow-up. Predictors of syncope recurrence have been evaluated at six months and 1 year from the syncope index by a multivariable logistic regression analysis. 348 patients were enrolled. Risk of syncope relapse was 9.2% at 6 months, 11.8% at 1 year, and 23.4% at 5 years. At 6-month follow-up, predictor of syncope recurrence was ≥3 prior lifetime syncope episodes. At 1-year, ≥3 prior lifetime syncope episodes, diabetes mellitus, and anaemia were risk factors for syncope relapse. There was an exceeding risk of recurrence in the first 6 months and a reduced risk of 3.5% per year after the first year. Anaemia, diabetes mellitus, and prior lifetime syncope burden are of importance when giving advice about the resumption of “high risk” jobs following a syncope episode. View Full-Text
Keywords: syncope; working activity; syncope recurrence risk factors; high-risk job; syncope in working-age syncope; working activity; syncope recurrence risk factors; high-risk job; syncope in working-age

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Barbic, F.; Dipaola, F.; Casazza, G.; Borella, M.; Minonzio, M.; Solbiati, M.; Raj, S.R.; Sheldon, R.; Quinn, J.; Costantino, G.; Furlan, R. Syncope in a Working-Age Population: Recurrence Risk and Related Risk Factors. J. Clin. Med. 2019, 8, 150.

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