Role of Vitamin A in the Immune System
Department of Pathology and Physiopathology, Guilin Medical University, Guilin 541004, Guangxi, China
Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin 541004, Guangxi, China
Research Service, VA Medical Center, Memphis, TN 38104, USA
Department of Medicine, Division of Rheumatology, Milton S. Hershey Medical Center at Penn State University, Hershey, PA 17033, USA
Author to whom correspondence should be addressed.
J. Clin. Med. 2018, 7(9), 258; https://doi.org/10.3390/jcm7090258
Received: 21 July 2018 / Revised: 23 August 2018 / Accepted: 31 August 2018 / Published: 6 September 2018
(This article belongs to the Section Immunology)
Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body. VitA is known as an anti-inflammation vitamin because of its critical role in enhancing immune function. VitA is involved in the development of the immune system and plays regulatory roles in cellular immune responses and humoral immune processes. VitA has demonstrated a therapeutic effect in the treatment of various infectious diseases. To better understand the relationship between nutrition and the immune system, the authors review recent literature about VitA in immunity research and briefly introduce the clinical application of VitA in the treatment of several infectious diseases.