Next Article in Journal
Update in Spontaneous Coronary Artery Dissection
Previous Article in Journal
The Emerging Role of Pathogenesis of IgA Nephropathy
Open AccessArticle

Perioperative Cumulative Fluid Balance and Its Association with an Increase in Costs after Major Surgery

1
Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam 13620, Korea
2
Department of Anesthesiology and Pain Medicine, College of Medicine, Seoul National University, 103 Daehak-ro, Jongno-gu, Seoul 03080, Korea
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2018, 7(9), 227; https://doi.org/10.3390/jcm7090227
Received: 6 July 2018 / Revised: 18 August 2018 / Accepted: 20 August 2018 / Published: 21 August 2018
(This article belongs to the Section Epidemiology & Public Health)
Positive fluid balance (FB) during the perioperative period may increase the incidence of postoperative complications, which may lead to longer hospitalization and higher hospital costs. However, a definitive association between positive FB and hospital costs has not yet been established. This retrospective observational study examined the association between perioperative FB and hospital costs of patients who underwent major surgical procedures. Medical records of patients who underwent major surgery (surgery time >2 h, estimated blood loss >500 mL) from January 2010 to December 2017 were analyzed to determine the associations between calculated FB (%, total input fluid—output fluid in liter/weight (kg) at admission) and total hospital cost ($). The analysis included medical data of 7010 patients. Multivariable linear regression analyses showed that a 1% increase in FB in postoperative day (POD) 0 (24 h), 0–1 (48 h), 0–2 (72 h), and 0–3 (96 h) significantly increased the total cost by $967.8 (95% confidence interval [CI]: 803.4–1132.1), $688.8 (95% CI: 566.3–811.2), $591 (95% CI: 485.7–696.4), and $434.2 (95% CI: 349.4–519.1), respectively (all p < 0.001). Perioperative cumulative FB was positively associated with hospital costs of patients who underwent major surgery. View Full-Text
Keywords: costs and cost analysis; general surgery; hospitals costs and cost analysis; general surgery; hospitals
Show Figures

Figure 1

MDPI and ACS Style

Oh, T.K.; Hwang, J.-W.; Jeon, Y.-T.; Do, S.-H. Perioperative Cumulative Fluid Balance and Its Association with an Increase in Costs after Major Surgery. J. Clin. Med. 2018, 7, 227.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop