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Open AccessArticle

Evaluation of Oral Mucositis Occurrence in Oncologic Patients under Antineoplastic Therapy Submitted to the Low-Level Laser Coadjuvant Therapy

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Programa de Pós-Graduação em Saúde Pública, Universidade Estadual da Paraíba, Avenida das Baraúnas, S/N—Campus Universitário, Bodocongó, Campina Grande 58109-753, Brazil
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Faculty of Medical Sciences, Campina Grande 58109-753, Brazil
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School of Dentistry, State University of Paraíba, Campina Grande 58109-753, Brazil
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Hospital Universitário Alcides Carneiro, Federal University of Campina Grande, Campina Grande 58109-753, Brazil
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Department of Dentistry, State University of Paraiba, Campina Grande 58109-753, Brazil
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Author to whom correspondence should be addressed.
J. Clin. Med. 2018, 7(5), 90; https://doi.org/10.3390/jcm7050090
Received: 31 March 2018 / Revised: 5 April 2018 / Accepted: 10 April 2018 / Published: 24 April 2018
(This article belongs to the Section Pharmacology)
Low-level laser therapy has been widely used in treating many conditions, including oral mucositis. The purpose of this study was to evaluate the occurrence of oral mucositis in patients undergoing antineoplastic therapy submitted to preventive and therapeutic treatment with low-level laser therapy. This cross-sectional study was carried out with 51 children and adolescents of both sexes with malignant neoplasias who developed oral mucositis and underwent low-level laser therapy. Data were collected on sex, age, type and degree of neoplasia, region affected, and remission time. 64.7% of the patients were male and were between 3 and 6 years of age (39.2%). Acute lymphoid leukemia was the most frequent neoplasm (37.3%). Regarding the maximum oral mucositis, grade 2 (41.2%) was predominant, with jugal mucosa (29.9%) and tongue (17.7%) being the most affected regions. The majority of cases presented lesion remission time between 4 and 7 days (44.0%). Most patients were young, male, and diagnosed with acute lymphoid leukemia. Predominance of grade 2 oral mucositis was observed, with jugal mucosa and tongue being the most affected regions, with the majority of cases presenting lesion remission time between 4 and 7 days. Low-level laser therapy has been shown to be an essential therapy in the prevention and treatment of these lesions, since it is a non-invasive and low-cost method. View Full-Text
Keywords: low-level laser therapy; mucositis; antineoplastic agents low-level laser therapy; mucositis; antineoplastic agents
MDPI and ACS Style

Leite Cavalcanti, A.; José de Macêdo, D.; Suely Barros Dantas, F.; Dos Santos Menezes, K.; Filipe Bezerra Silva, D.; Alves de Melo Junior, W.; Fabia Cabral Cavalcanti, A. Evaluation of Oral Mucositis Occurrence in Oncologic Patients under Antineoplastic Therapy Submitted to the Low-Level Laser Coadjuvant Therapy. J. Clin. Med. 2018, 7, 90.

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