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Safety, Efficacy and Evidence Base for Use of the Subcutaneous Implantable Cardioverter Defibrillator

Division of Cardiology, Department of Clinical and Molecular Medicine, Sapienza University of Rome, St. Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy
Author to whom correspondence should be addressed.
J. Clin. Med. 2018, 7(3), 53;
Received: 28 December 2017 / Revised: 16 February 2018 / Accepted: 6 March 2018 / Published: 11 March 2018
(This article belongs to the Special Issue Advances in Interventional Cardiology and Vascular Medicine)
The trans-venous implantable cardioverter defibrillator (TV-ICD) is effective in treating life-threatening ventricular arrhythmia and reduces mortality in high-risk patients. However, there are significant short- and long-term complications that are associated with intravascular leads. These shortcomings are mostly relevant in young patients with long life expectancy and low risk of death from non-arrhythmic causes. Drawbacks of trans-venous leads recently led to the development of the entirely subcutaneous implantable cardioverter defibrillator (S-ICD). The S-ICD does not require vascular access or permanent intravascular defibrillation leads. Therefore, it is expected to overcome many complications associated with conventional ICDs. This review highlights data on safety and efficacy of the S-ICD and is envisioned to help in identifying the role of this device in clinical practice. View Full-Text
Keywords: subcutaneous ICD; transvenous leads; sudden cardiac death subcutaneous ICD; transvenous leads; sudden cardiac death
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Adduci, C.; Palano, F.; Francia, P. Safety, Efficacy and Evidence Base for Use of the Subcutaneous Implantable Cardioverter Defibrillator. J. Clin. Med. 2018, 7, 53.

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