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Biological Treatments in Atopic Dermatitis

Department of Dermatology, Hospital Universitario de La Princesa, Diego de León 62, Madrid 28006, Spain
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Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editors: Sebastien Barbarot and Kim Thomas
J. Clin. Med. 2015, 4(4), 593-613; https://doi.org/10.3390/jcm4040593
Received: 31 January 2015 / Revised: 3 March 2015 / Accepted: 13 March 2015 / Published: 3 April 2015
(This article belongs to the Special Issue Epidemiology and Treatment of Atopic Eczema)
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases that affect both children and adults with a prevalence of 30% and 10%, respectively. Even though most of patients respond satisfactory to topical anti-inflammatory drugs, about 10% require one or more systemic treatments to achieve good control of their illness. The progressive and increasingly detailed knowledge in the immunopathogenesis of AD has allowed research on new therapeutic targets with very promising results in the field of biological therapy. In this article, we will review the different biological treatments with a focus on novel drugs. Their mechanism of action, current status and results from clinical trials and observational studies will be specified. View Full-Text
Keywords: atopic eczema; atopic dermatitis; pathogenesis; biologics; antibody therapy atopic eczema; atopic dermatitis; pathogenesis; biologics; antibody therapy
MDPI and ACS Style

Montes-Torres, A.; Llamas-Velasco, M.; Pérez-Plaza, A.; Solano-López, G.; Sánchez-Pérez, J. Biological Treatments in Atopic Dermatitis. J. Clin. Med. 2015, 4, 593-613.

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