Artificial Intelligence in Oral and Maxillofacial Surgery: Integrating Clinical Innovation and Workflow Optimization
Abstract
1. Introduction
2. Materials and Methods
3. Results
3.1. Imaging and Planning
AI Applications in Diagnosis and Surgical Planning
3.2. Risk Prediction
| Domain of Application | Reported Clinical Benefits | Key Limitations | Validation Status |
|---|---|---|---|
| TMD classification (MRI + clinical data) [13,14] | Higher sensitivity/specificity in diagnosis; improved treatment selection | Limited datasets; mostly experimental | Pilot studies; not yet multicenter |
| Third molar extraction difficulty & nerve injury risk [2] | Stratifies extraction difficulty; flags high-risk cases | Accuracy may vary across populations; not fully validated | Early validation; small sample cohorts |
| Intraoperative AR & navigation | Real-time guidance, enhanced precision in extractions and reconstructions [1,3] | Experimental; limited availability and high cost | Pilot studies, early-stage prototypes |
| Custom implant & biomaterials design | Patient-specific prosthetics, safer resorbable implants, reduced imaging artifacts [10] | Specialized applications; lack of large-scale trials | Preclinical and early clinical validation |
| Imaging pathology detection (cysts, tumors, lesions [2] | Comparable accuracy to oral radiologists (>90% in some tests) | May misclassify atypical/pediatric cases | Scoping reviews; controlled tests only |
| Imaging enhancement & artifact reduction [2] | Noise reduction, clearer radiographs, better planning | Limited generalizability; vendor-specific | Prototype tools; early adoption |
| EHR-based predictive analytics [18] | Identifies missed appointments, complications, incomplete treatments | Dependent on data quality and integration | Reported in general dentistry; limited OMFS-specific validation |
3.3. Administrative Workflow
3.4. Patient Communication
4. Discussion
- Augment, not replace: AI should reduce mechanical burdens and free clinicians to focus on empathy, judgment, and care.
- Implement responsibly: cost-effectiveness, transparency, and staff training are as important as accuracy metrics.
- Maintain oversight: ultimate responsibility rests with the surgeon, ensuring technology serves the patient rather than dictates care.
Clinical Implication
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A





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| Domain of Application | Reported Clinical Benefits | Key Limitations | Validation Status |
|---|---|---|---|
| Automated imaging segmentation (CT, CBCT, MRI) | Faster landmark identification, reduced manual workload, improved consistency [1,9] | Dependent on dataset quality; less robust in atypical cases | Early clinical validation; small cohorts |
| Virtual surgical planning (VSP) & generative design | Sub-millimeter prediction of soft tissue changes, improved implant fit, reduced intraoperative adjustments [2,10,12] | Limited multicenter and pediatric data | Reported in >100 clinical cases (e.g., orbital floor reconstructions) |
| Intraoperative AR & navigation | Real-time guidance, enhanced precision in extractions and reconstructions [1,3] | Experimental; limited availability and high cost | Pilot studies, early-stage prototypes |
| Custom implant & biomaterials design | Patient-specific prosthetics, safer resorbable implants, reduced imaging artifacts [10] | Specialized applications; lack of large-scale trials | Preclinical and early clinical validation |
| Domain of Application | Reported Clinical Benefits | Key Limitations | Validation Status |
|---|---|---|---|
| Patient triage & virtual intake [4,5,15,19] | Faster emergency detection; automated sorting of routine cases | Requires clinical oversight; risk of misclassification | Early prototypes; small-scale studies |
| Automated documentation & transcription [1,4,6,7,9,16,17] | Saves 10–15 min per patient; standardized notes; improved compliance | Needs human review; terminology/context errors | Early adoption; healthcare pilot studies |
| Internal staff support chatbots [5,20] | Quick access to protocols; reduced training time; fewer errors | Limited validation; dependent on knowledge base quality | Prototype implementations |
| Operational analytics (e.g., wait times, cancelations) [5,20] | Real-time monitoring; proactive problem-solving | Still experimental; integration challenges | Research/early pilot stage |
| Domain of Application | Reported Clinical Benefits | Key Limitations | Validation Status |
|---|---|---|---|
| Chatbots & virtual assistants [4,5,18] | 24/7 responses; faster answers; higher patient satisfaction | Must hand off complex/emotional cases; risk of misunderstanding | Early clinical deployments; mixed-methods evaluations |
| AI-simplified reports & education [8,21,22,23] | Better understanding; higher preparedness; improved satisfaction | Needs clinician review for accuracy; variable literacy levels | Randomized/controlled usability studies |
| Telemedicine “AI co-pilot” & decision support [6,16] | Real-time transcription/prompts; more comprehensive consults | Largely conceptual/prototype; integration burden | Commentaries, pilot platforms |
| Postoperative monitoring & PROs [18] | Earlier complication flags; improved outreach | False positives, alert fatigue | Prospective app-based studies |
| Human-centered safeguards [20] | Preserves trust; clear boundaries for automation | Requires governance and training | Expert guidance, implementation reports |
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© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Rana, M.; Sakkas, A.; Zimmermann, M.; Kostyuk, M.; Schwarz, G. Artificial Intelligence in Oral and Maxillofacial Surgery: Integrating Clinical Innovation and Workflow Optimization. J. Clin. Med. 2026, 15, 427. https://doi.org/10.3390/jcm15020427
Rana M, Sakkas A, Zimmermann M, Kostyuk M, Schwarz G. Artificial Intelligence in Oral and Maxillofacial Surgery: Integrating Clinical Innovation and Workflow Optimization. Journal of Clinical Medicine. 2026; 15(2):427. https://doi.org/10.3390/jcm15020427
Chicago/Turabian StyleRana, Majeed, Andreas Sakkas, Matthias Zimmermann, Maurício Kostyuk, and Guilherme Schwarz. 2026. "Artificial Intelligence in Oral and Maxillofacial Surgery: Integrating Clinical Innovation and Workflow Optimization" Journal of Clinical Medicine 15, no. 2: 427. https://doi.org/10.3390/jcm15020427
APA StyleRana, M., Sakkas, A., Zimmermann, M., Kostyuk, M., & Schwarz, G. (2026). Artificial Intelligence in Oral and Maxillofacial Surgery: Integrating Clinical Innovation and Workflow Optimization. Journal of Clinical Medicine, 15(2), 427. https://doi.org/10.3390/jcm15020427

