Management of Bleeding, Thrombotic and Pregnancy-Related Complications in Women with Myeloproliferative Neoplasms: A Case-Based Review Focusing on Sex-Specific Challenges
Abstract
:1. Introduction
2. Bleeding in Women with MPNs
2.1. The Challenge of Assessment of Bleeding in MPNs
2.2. Risk Factors for MPN Bleeding
2.3. Mechanisms for Bleeding
2.4. Management of Bleeding
3. Thrombosis in Women with MPNs
4. MPNs and Pregnancy
4.1. MPN and Fertility
4.2. Pregnancy Outcomes and Their Prediction in MPN
4.3. Management of MPN in Pregnancy
4.3.1. Preconception Counseling
4.3.2. Risk Stratification
4.3.3. Antepartum Monitoring and Treatment
4.3.4. Prevention of Peripartum Bleeding
4.3.5. Postpartum Management
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Female patients |
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Male patients |
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High-risk MPN |
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History of pregnancy morbidity |
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Challenges | Management Approaches | |
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Bleeding |
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Thrombosis |
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Fertility |
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Pregnancy and postpartum |
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© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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Chiasakul, T.; Baker, R.I. Management of Bleeding, Thrombotic and Pregnancy-Related Complications in Women with Myeloproliferative Neoplasms: A Case-Based Review Focusing on Sex-Specific Challenges. J. Clin. Med. 2025, 14, 1537. https://doi.org/10.3390/jcm14051537
Chiasakul T, Baker RI. Management of Bleeding, Thrombotic and Pregnancy-Related Complications in Women with Myeloproliferative Neoplasms: A Case-Based Review Focusing on Sex-Specific Challenges. Journal of Clinical Medicine. 2025; 14(5):1537. https://doi.org/10.3390/jcm14051537
Chicago/Turabian StyleChiasakul, Thita, and Ross I. Baker. 2025. "Management of Bleeding, Thrombotic and Pregnancy-Related Complications in Women with Myeloproliferative Neoplasms: A Case-Based Review Focusing on Sex-Specific Challenges" Journal of Clinical Medicine 14, no. 5: 1537. https://doi.org/10.3390/jcm14051537
APA StyleChiasakul, T., & Baker, R. I. (2025). Management of Bleeding, Thrombotic and Pregnancy-Related Complications in Women with Myeloproliferative Neoplasms: A Case-Based Review Focusing on Sex-Specific Challenges. Journal of Clinical Medicine, 14(5), 1537. https://doi.org/10.3390/jcm14051537