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Editorial

A Focus on Personalized Care in Light of New Diagnostic and Therapeutic Pathways of Shoulder and Elbow Disease

by
Teresa Paolucci
1,2,3,*,
Alice Cichelli
1 and
Massimiliano Mangone
4
1
Department of Oral Medical Sciences and Biotechnology, University of the Study G. D’Annunzio of Chieti and Pescara (UDA), Physical and Rehabilitation Medicine, 66100 Chieti, Italy
2
S. Spirito Hospital of Pescara, 65124 Pescara, Italy
3
Center for Disability, Rehabilitation, and Sports Medicine, University of G. D’Annunzio of Chieti and Pescara, Physical and Rehabilitation Medicine, 66100 Chieti, Italy
4
Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University, 00185 Rome, Italy
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2025, 14(5), 1425; https://doi.org/10.3390/jcm14051425
Submission received: 5 February 2025 / Accepted: 18 February 2025 / Published: 20 February 2025
(This article belongs to the Special Issue Targeted Diagnosis and Treatment of Shoulder and Elbow Disease)
The shoulder is a complex system of functionally interconnected and coordinated joints. Together with the elbow joint and the hand, it guides and stabilizes the reaching movement of the upper limb. The functional role of the shoulder and elbow is twofold: to provide stability to the joint complex and to allow for a wide range of motion in the shoulder girdle and, through the elbow joint, to allow for quick and precise movements. These conditions—“stability”, “freedom of movement”, and “speed”—are lost if any of the numerous anatomical components are damaged by trauma, inflammation, or the peripheral or central nervous system.
Rotator cuff injuries, whether traumatic or due to functional overload, arthrosis, and heterotopic ossification, are the most common pathologies of the shoulder complex, while specific tendinopathies, with or without heterotopic ossification, are syndromes that specifically affect the elbow [1,2,3,4].
From these premises, the idea of promoting a Special Issue dedicated to “Diagnosis and Treatment of Shoulder and Elbow Disease” was born, which led to interesting reflections in light of the new diagnostic, surgical, and rehabilitative treatment proposals on this topic.
Eight papers were included in this Special Issue that address the topics presented in Figure 1.
There have been some insightful reflections on the use of Artificial Intelligence (AI) [5], in particular language models such as ChatGPT and Gemini, to support medical decision making in hand surgery. This underscores the importance of assessing the strengths and limitations of different models when incorporating them into clinical practice. However, more research is needed to evaluate the use and performance of additional AI tools (Pressman S.M. et al.). In addition, advances in arthroscopic techniques for repairing isolated subscapularis tendon tears [6] have become increasingly popular in recent years. Specifically, arthroscopic repair has been shown to achieve clinical and structural outcomes equivalent to the gold standard of open repair (Bartl C. et al.). Rehabilitation after rotator cuff repair is essential for functional recovery and to reduce the risk of retear [7,8]. The review by T. Paolucci et al. found that both early and delayed rehabilitation protocols after arthroscopic rotator cuff repair can provide adequate pain relief and functional recovery. However, early rehabilitation protocols generally result in better short-term improvements in range of motion and strength. These benefits may not last, and the risk of recurrence remains a concern with early rehabilitation, especially for major injuries. Clinicians should carefully evaluate each patient’s individual characteristics, injury severity, and specific therapy modalities to determine the most appropriate rehabilitation protocol following rotator cuff repair. Shoulder pain is a common musculoskeletal condition, accounting for approximately 1.3% of all primary care visits. When conservative and pharmacologic treatments fail, arthrodesis is typically considered a salvage procedure with limited functional goals. However, in “selected” patients, it can provide effective pain relief, stable motion, and satisfactory functional outcomes [9]. In the patient series by Sobhi, S. et al., shoulder arthrodesis demonstrated remarkable efficacy in pain reduction, high patient satisfaction, and acceptable functional outcomes with manageable complication rates. Considering that chronic shoulder pain can lead to significant functional disability and reduced psychosocial well-being, often exacerbated by kinesiophobia (Alito A. et al.), these findings highlight the potential benefits of this procedure in appropriately selected patients. Pathology of the long head of the biceps (LHBs) tendon is a common cause of anterior shoulder pain, including tendinitis, tenosynovitis, subluxation, dislocation, and tears [8]. In the pathogenesis of LHBs tendon instability, a shallow intertubercular groove morphology has been identified as a potential predisposing factor. Gerhardinger K. et al. suggested that the dimensions of the LHBs tendon may also influence instability, and they introduced the tendon-to-groove cross-sectional area ratio as a novel parameter to describe individual local anatomy. Heterotopic ossification (HO) after elbow trauma can result in significant motion restriction, depending on the size and location of the HO, as seen on radiographs [10]. On this specific topic, Leyder D. et al. introduced a novel classification that provides more detailed insights compared to previously established systems and aims to assist clinicians in making treatment decisions. Finally, Longo U.G. et al. proposed a minimal clinically important difference (MCID) for the 36-item Short-Form Health Survey (SF-36) questionnaire to assess patient-acceptable symptom status (PASS) during both preoperative evaluation and final follow-up after surgical shoulder repair.
We hope that you enjoy reading the articles published within this Special Issue.

Author Contributions

Conceptualization, writing, original draft preparation, and editing: T.P., A.C. and M.M. All authors have read and agreed to the published version of this manuscript.

Conflicts of Interest

The authors declare that the collation of this Special Issue was conducted in the absence of any commercial or financial relationships that could be construed as potential conflicts of interest.

List of Contributions

  • Bartl, C.; Dolde, J.; Gebhard, F.; Eichhorn, S.; Hainzer, L.; Pauly, S. Clinical and Structural Results Following Arthroscopic and Open Repair of Isolated Subscapularis Tears. J. Clin. Med. 2024, 13, 6589. https://doi.org/10.3390/jcm13216589.
  • Sobhi, S.; Bochat, K.; Booth, G.; Mattin, A.; Moniz, S. Clinical and Surgical Outcomes of Shoulder Arthrodesis. J. Clin. Med. 2024, 13, 4701. https://doi.org/10.3390/jcm13164701.
  • Gerhardinger, K.; Klute, L.; Pfeifer, C.; Straub, J.; Hechinger, L.; Riedl, M.; Alt, V.; Kerschbaum, M.; Henssler, L. Is the Tendon-to-Groove Ratio Associated with Elevated Risk for LHB Tendon Disorders?—A New Approach of Preoperative MR-Graphic Analysis for Targeted Diagnosis of Tendinopathy of the Long Head of Biceps. J. Clin. Med. 2024, 13, 2860. https://doi.org/10.3390/jcm13102860.
  • Pressman, S.M.; Borna, S.; Gomez-Cabello, C.A.; Haider, S.A.; Forte, A.J. AI in Hand Surgery: Assessing Large Language Models in the Classification and Management of Hand Injuries. J. Clin. Med. 2024, 13, 2832. https://doi.org/10.3390/jcm13102832.
  • Leyder, D.; Döbele, S.; Konrads, C.; Histing, T.; Fischer, C.S.; Ahrend, M.-D.; Ziegler, P. Classification and Incidence of Heterotopic Ossifications in Relation to NSAID Prophylaxis after Elbow Trauma. J. Clin. Med. 2024, 13, 667. https://doi.org/10.3390/jcm13030667.
  • Longo, U.G.; De Salvatore, S.; Piergentili, I.; Lalli, A.; Bandini, B.; Denaro, V. Minimum Clinically Important Difference (MCID) and Patient Acceptable Symptomatic State (PASS) Applied to the SF-36 in Patients Who Underwent Arthroscopic Rotator Cuff Repair. J. Clin. Med. 2024, 13, 178. https://doi.org/10.3390/jcm13010178.
  • Paolucci, T.; Agostini, F.; Conti, M.; Cazzolla, S.; Mussomeli, E.; Santilli, G.; Poso, F.; Bernetti, A.; Paoloni, M.; Mangone, M. Comparison of Early versus Traditional Rehabilitation Protocol after Rotator Cuff Repair: An Umbrella-Review. J. Clin. Med. 2023, 12, 6743. https://doi.org/10.3390/jcm12216743.
  • Alito, A.; Cifalinò, M.E.; Fontana, J.M.; Verme, F.; Piterà, P.; Capodaglio, P. Tackling Kinesiophobia in Chronic Shoulder Pain: A Case Report on the Combined Effect of Pain Education and Whole-Body Cryostimulation. J. Clin. Med. 2024, 13, 2094. https://doi.org/10.3390/jcm13072094.

References

  1. Mall, N.A.; Chahal, J.; Heard, W.M.; Bach, B.R., Jr.; Bush-Joseph, C.A.; Romeo, A.A.; Verma, N.N. Outcomes of arthroscopic and open surgical repair of isolated subscapularis tendon tears. Arthroscopy 2012, 28, 1306–1314. [Google Scholar] [CrossRef] [PubMed]
  2. de Sire, A.; Agostini, F.; Bernetti, A.; Mangone, M.; Ruggiero, M.; Dinatale, S.; Chiappetta, A.; Paoloni, M.; Ammendolia, A.; Paolucci, T. Non-Surgical and Rehabilitative Interventions in Patients with Frozen Shoulder: Umbrella Review of Systematic Reviews. J. Pain Res. 2022, 19, 2449–2464. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
  3. Li, L.; Sun, Y.; Qin, H.; Zhou, J.; Yang, X.; Li, A.; Zhang, J.; Zhang, Y. A scientometric analysis and visualization of kinesiophobia research from 2002 to 2022: A review. Medicine 2023, 102, e35872. [Google Scholar] [CrossRef] [PubMed]
  4. Heuts, P.H.; Vlaeyen, J.W.; Roelofs, J.; de Bie, R.A.; Aretz, K.; van Weel, C.; van Schayck, O.C. Pain-related fear and daily functioning in patients with osteoarthritis. Pain 2004, 110, 228–235. [Google Scholar] [CrossRef] [PubMed]
  5. Miller, R.; Farnebo, S.; Horwitz, M.D. Insights and trends review: Artificial intelligence in hand surgery. J. Hand Surg. Eur. Vol. 2023, 48, 396–403. [Google Scholar] [CrossRef]
  6. Nazari, G.; MacDermid, J.C.; Bryant, D.; Dewan, N.; Athwal, G.S. Effects of arthroscopic vs. mini-open rotator cuff repair on function, pain & range of motion. A systematic review and meta-analysis. PLoS ONE 2019, 14, e0222953. [Google Scholar]
  7. Littlewood, C.; Bateman, M.; Butler-Walley, S.; Bathers, S.; Bromley, K.; Lewis, M.; Funk, L.; Denton, J.; Moffatt, M.; Winstanley, R.; et al. Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR). Clin. Rehabil. 2021, 35, 829–839. [Google Scholar] [PubMed]
  8. Van Deurzen, D.F.P.; Garssen, F.L.; Kerkhoffs, G.M.M.J.; Bleys, R.L.A.W.; Ten Have, I.; van den Bekerom, M.P.J. Clinical relevance of the anatomy of the long head bicipital groove, an evidence-based review. Clin. Anat. 2021, 34, 199–208. [Google Scholar] [CrossRef]
  9. Del Core, M.A.; Cutler, H.S.; Schacherer, T.; Khazzam, M. Glenohumeral arthrodesis. JSES Rev. Rep. Tech. 2021, 1, 367–372. [Google Scholar] [CrossRef] [PubMed]
  10. Wiggers, J.K.; Helmerhorst, G.T.; Brouwer, K.M.; Niekel, M.C.; Nunez, F.; Ring, D. Injury complexity factors predict heterotopic ossification restricting motion after elbow trauma. Clin. Orthop. Relat. Res. 2014, 472, 2162–2167. [Google Scholar] [CrossRef] [PubMed]
Figure 1. Topics of the included papers.
Figure 1. Topics of the included papers.
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MDPI and ACS Style

Paolucci, T.; Cichelli, A.; Mangone, M. A Focus on Personalized Care in Light of New Diagnostic and Therapeutic Pathways of Shoulder and Elbow Disease. J. Clin. Med. 2025, 14, 1425. https://doi.org/10.3390/jcm14051425

AMA Style

Paolucci T, Cichelli A, Mangone M. A Focus on Personalized Care in Light of New Diagnostic and Therapeutic Pathways of Shoulder and Elbow Disease. Journal of Clinical Medicine. 2025; 14(5):1425. https://doi.org/10.3390/jcm14051425

Chicago/Turabian Style

Paolucci, Teresa, Alice Cichelli, and Massimiliano Mangone. 2025. "A Focus on Personalized Care in Light of New Diagnostic and Therapeutic Pathways of Shoulder and Elbow Disease" Journal of Clinical Medicine 14, no. 5: 1425. https://doi.org/10.3390/jcm14051425

APA Style

Paolucci, T., Cichelli, A., & Mangone, M. (2025). A Focus on Personalized Care in Light of New Diagnostic and Therapeutic Pathways of Shoulder and Elbow Disease. Journal of Clinical Medicine, 14(5), 1425. https://doi.org/10.3390/jcm14051425

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