Supportive Text Messaging and Peer Support for Patients in the 6 Months Following Discharge from a Psychiatric Admission: Mental Health Outcomes from a Cluster-Randomized Controlled Trial
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Setting and Design
2.2. Data Collection and Inclusion Criteria
2.3. Ethics Statement
2.4. Sample Size Calculation
2.5. Outcome Measures
2.5.1. Generalized Anxiety Disorder Scale (GAD-7)
2.5.2. Patient Health Questionnaire (PHQ-9)
2.5.3. World Health Organization-Five Well-Being Index (WHO-5)
2.6. Statistical Analysis
3. Results
3.1. Summary of Study Recruitment and Enrollment
3.2. Baseline Data Analysis
3.3. ANOVA Analysis
| Variable | TAU (M ± SD) | SMS (M ± SD) | SMS+PS (M ± SD) | Chi Square | df | p-Value |
|---|---|---|---|---|---|---|
| GAD-7 | 8.78 ± 5.76 | 8.32 ± 5.71 | 7.77 ± 4.67 | 8.94 | 2 | 0.01 * |
| PHQ-9 | 11.01 ± 6.56 | 11.39 ± 6.80 | 11.26 ± 5.27 | 1.86 | 2 | 0.40 |
| WHO-5 | 51.68 ± 23.38 | 52.02 ± 23.43 | 47.80 ± 21.33 | 3.62 | 2 | 0.16 |
| Suicidal Ideation | 0.76 ± 0.96 | 0.79 ± 0.99 | 0.75 ± 0.81 | 7.51 | 6 | 0.75 |
| Sleep Issues | 1.44 ± 1.06 | 1.48 ± 1.04 | 1.49 ± 0.86 | 3.47 | 6 | 0.28 |
3.4. ANCOVA Analysis
4. Discussion
5. Limitations
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| ED | Emergency Department |
| CIHI | Canadian Institute for Health Information |
| TAU | Treatment as Usual |
| SMS | Supportive Text Messaging |
| SMS+PS | Supportive Text Messaging Plus Peer Support |
| ORs | Odds Ratios |
| CIs | Confidence Intervals |
| GAD-7 | Generalized Anxiety Disorder Scale |
| PHQ-9 | Patient Health Questionnaire |
| WHO-5 | World Health Organization-Five Well-Being Index |
| ANCOVA | Analysis of Covariance |
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| Variables | Treatment Groups | |||
|---|---|---|---|---|
| TAU (n = 439) n (%) = 40.0% | SMS (n = 541) n (%) = 49.3% | SMS+PS (n = 118) n (%) = 10.7% | Total (n = 1098) | |
| Age 18–25 y 26–40 y >40 y | 116 (26.4) 168 (38.3) 155 (35.3) | 226 (41.8) 180 (33.3) 135 (25.0) | 59 (50.0) 28 (23.7) 31 (26.3) | 401 (36.5) 376 (34.2) 321 (29.2) |
| Gender Male Female Other Gender | 201 (45.8) 225 (51.3) 13 (3.0) | 227 (42.0) 301 (55.6) 13 (2.4) | 40 (33.9) 72 (61.0) 6 (5.1) | 468 (42.6) 598 (54.5) 32 (2.9) |
| Ethnicity Caucasian Indigenous Black people Asian Mixed/Other | 281 (64.0) 44 (10.0) 44 (10.0) 45 (10.3) 25 (5.7) | 323 (59.7) 48 (8.9) 63 (11.6) 66 (12.2) 41 (7.6) | 71(60.2) 10 (8.5) 13 (11.0) 14 (11.9) 10 (8.5) | 675 (61.5) 102 (9.3) 120 (10.9) 125 (11.4) 76 (6.9) |
| Education Level Less than High School High School Diploma Post-secondary Education Prefer not to say | 22 (5.0) 211 (48.1) 197 (44.9) 9 (2.1) | 15 (2.8) 286 (52.9) 221 (40.9) 19 (3.5) | 4 (3.4) 68 (57.6) 40 (33.9) 6 (5.1) | 41 (3.7) 565 (51.5) 458 (41.7) 34 (3.1) |
| Relationship Status Married/Partnered/Common-Law Single Separated or Divorced Widowed Prefer not to say | 103 (29.6) 256 (58.3) 39 (8.9) 6 (1.4) 8 (1.8) | 160 (29.6) 323 (59.7) 39 (7.2) 3 (0.6) 16 (3.0) | 31 (26.3) 68 (57.6) 8 (6.8) 3 (2.5) 8 (6.8) | 321 (29.2) 647 (58.9) 86 (7.8) 12 (1.1) 32 (2.9) |
| Employment status Employed Unemployed Student Retired Other | 139 (31.7) 236 (53.8) 21 (4.8) 34 (7.7) 9 (2.1) | 156 (28.8) 283 (52.3) 56 (10.4) 26 (4.8) 20 (3.7) | 31 (26.3) 62 (52.5) 12 (10.2) 6 (5.1) 7 (5.9) | 326 (29.7) 585 (52.9) 89 (8.1) 68 (6.0) 36 (3.3) |
| Housing Status Own Home Rented Accommodation Live with Family or Friend Couchsurfing/Shelter/Street/Other | 105 (23.9) 148 (33.7) 159 (36.2) 27 (6.2) | 98 (18.1) 169 (31.3) 238 (44.1) 35 (6.5) | 15 (12.7) 36 (30.5) 61 (51.7) 6 (5.1) | 218 (19.9) 355 (32.2) 458 (41.8) 68 (6.2) |
| Primary Mental Health Diagnosis Depression Bipolar Disorder Anxiety Schizophrenia Personality Disorder Substance Use Disorder Other | 129 (29.4) 74 (16.9) 55 (12.5) 71 (16.2) 28 (6.4) 10 (2.3) 72 (16.4) | 140 (25.9) 126 (23.3) 65 (12.0) 88 (16.3) 53 (9.8) 5 (0.9) 63(11.7) | 21 (17.8) 23 (19.5) 21 (17.8) 19 (16.1) 24 (20.3) 0 (0.0) 10 (8.5) | 290 (26.4) 223 (20.3) 141 (12.9) 178 (16.2) 105 (9.6) 15 (1.4) 145 (13.2) |
| Measures | Descriptives | ANCOVA Parameters | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline Mean (SD) | 6-Weeks Mean (SE) | 3-Months Mean (SE) | 6-Months Mean (SE) | ||||||||||||||||||
| TAU | SMS | SMS+PS | TAU | SMS | SMS+PS | F Value (df) | p-Value | Partial eta | TAU | SMS | SMS+PS | F Value (df) | p-Value | Partial eta | TAU | SMS | SMS+PS | F Value (df) | p-Value | Partial eta | |
| GAD-7 | 8.78 (5.76) | 8.32 (5.71) | 7.77 (4.67) | 9.05 (0.68) | 8.65 (0.66) | 8.54 (1.16) | 0.12 | 0.89 | 0.00 | 10.09 (0.76) | 9.17 (1.19) | 9.58 (1.53) | 0.23 | 0.80 | 0.00 | 8.24 (0.88) | 7.58 (0.74) | 9.83 (1.58) | 2.78 | 0.01 * | 0.10 |
| PHQ-9 | 11.01 (6.56) | 11.39 (6.80) | 11.26 (5.27) | 12.51 (0.77) | 11.07 (0.75) | 11.61 (1.24) | 0.91 | 0.40 | 0.01 | 12.84 (0.96) | 11.75 (1.22) | 11.97 (1.94) | 0.28 | 0.76 | 0.00 | 11.42 (1.11) | 11.08 (0.95) | 11.64 (1.73) | 2.50 | 0.03 * | 0.09 |
| WHO-5 | 51.68 (23.38) | 52.02 (23.43) | 47.80 (21.33) | 46.88 (2.50) | 49.48 (2.40) | 44.78 (4.02) | 4.24 | 0.00 | 0.10 | 48.24 (3.00) | 47.24 (3.82) | 42.07 (6.12) | 1.89 | 0.09 | 0.06 | 47.95 (3.46) | 50.31 (2.95) | 48.78 (5.39) | 0.14 | 0.87 | 0.00 |
| Suicidal Ideation | 0.76 (0.96) | 0.79 (0.99) | 0.75 (0.81) | 0.93 (0.11) | 0.74 (0.11) | 0.65 (0.18) | 1.15 | 0.32 | 0.01 | 1.11 (0.31) | 1.00 (0.40) | 0.75 (0.63) | 0.14 | 0.87 | 0.00 | 0.79 (0.14) | 0.82 (0.12) | 1.25 (0.22) | 2.00 | 0.07 | 0.07 |
| Sleep Issues | 1.44 (1.06) | 1.48 (1.04) | 1.49 (0.86) | 1.55 (0.13) | 1.47 (0.13) | 1.61 (0.21) | 0.18 | 0.84 | 0.00 | 1.80 (0.76) | 2.09 (0.96) | 1.52 (1.53) | 0.06 | 0.094 | 0.00 | 1.66 (0.21) | 1.61 (0.18) | 1.66 (0.33) | 0.72 | 0.63 | 0.03 |
| Measures | Study Groups | Paired Groups | Mean Difference | S.E | p-Value | 95% Confidence Interval for Difference | |
|---|---|---|---|---|---|---|---|
| Lower Bound | Upper Bound | ||||||
| GAD-7 | TAU | SMS | 0.67 | 1.51 | 0.56 | −1.61 | 2.94 |
| PS | −1.59 | 1.81 | 0.38 | −5.18 | 2.00 | ||
| SMS | TAU | −0.67 | 1.51 | 0.56 | −2.94 | 1.61 | |
| PS | −2.26 | 1.75 | 0.20 | −5.71 | 1.20 | ||
| PS | TAU | 1.59 | 1.81 | 0.38 | −2.00 | 5.18 | |
| SMS | 2.26 | 1.75 | 0.20 | −1.20 | 5.71 | ||
| PHQ-9 | TAU | SMS | 0.35 | 1.46 | 0.81 | −4.27 | 3.84 |
| PS | −0.21 | 2.05 | 0.92 | −4.27 | 3.84 | ||
| SMS | TAU | −0.35 | 2.46 | 0.81 | −3.23 | 2.53 | |
| PS | −0.56 | 1.97 | 0.78 | −4.44 | 3.33 | ||
| PS | TAU | 0.21 | 2.05 | 0.92 | −3.84 | 4.27 | |
| SMS | 0.56 | 1.97 | 0.78 | −3.33 | 4.44 | ||
| WHO-5 | TAU | SMS | −2.33 | 4.55 | 0.61 | −11.31 | 6.65 |
| PS | −0.80 | 6.41 | 0.90 | −13.46 | 11.86 | ||
| SMS | TAU | 2.33 | 4.55 | 0.61 | −6.65 | 11.31 | |
| PS | 1.53 | 6.14 | 0.80 | −10.60 | 13.65 | ||
| PS | TAU | 0.80 | 6.41 | 0.90 | −11.86 | 13.46 | |
| SMS | −1.53 | 6.14 | 0.80 | −13.65 | 10.60 | ||
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Mao, W.; Shalaby, R.; Owusu, E.; Elgendy, H.E.; Agyapong, B.; Silverstone, P.H.; Li, X.-M.; Greenshaw, A.J.; Eboreime, E.; Vuong, W.; et al. Supportive Text Messaging and Peer Support for Patients in the 6 Months Following Discharge from a Psychiatric Admission: Mental Health Outcomes from a Cluster-Randomized Controlled Trial. J. Clin. Med. 2025, 14, 8262. https://doi.org/10.3390/jcm14238262
Mao W, Shalaby R, Owusu E, Elgendy HE, Agyapong B, Silverstone PH, Li X-M, Greenshaw AJ, Eboreime E, Vuong W, et al. Supportive Text Messaging and Peer Support for Patients in the 6 Months Following Discharge from a Psychiatric Admission: Mental Health Outcomes from a Cluster-Randomized Controlled Trial. Journal of Clinical Medicine. 2025; 14(23):8262. https://doi.org/10.3390/jcm14238262
Chicago/Turabian StyleMao, Wanying, Reham Shalaby, Ernest Owusu, Hossam Eldin Elgendy, Belinda Agyapong, Peter H. Silverstone, Xin-Min Li, Andrew J. Greenshaw, Ejemai Eboreime, Wesley Vuong, and et al. 2025. "Supportive Text Messaging and Peer Support for Patients in the 6 Months Following Discharge from a Psychiatric Admission: Mental Health Outcomes from a Cluster-Randomized Controlled Trial" Journal of Clinical Medicine 14, no. 23: 8262. https://doi.org/10.3390/jcm14238262
APA StyleMao, W., Shalaby, R., Owusu, E., Elgendy, H. E., Agyapong, B., Silverstone, P. H., Li, X.-M., Greenshaw, A. J., Eboreime, E., Vuong, W., Ohinmaa, A., & Agyapong, V. I. O. (2025). Supportive Text Messaging and Peer Support for Patients in the 6 Months Following Discharge from a Psychiatric Admission: Mental Health Outcomes from a Cluster-Randomized Controlled Trial. Journal of Clinical Medicine, 14(23), 8262. https://doi.org/10.3390/jcm14238262

