Adding Multimedia Animations to Exercise Therapy Provides No Additional Benefit for Rotator Cuff–Related Shoulder Pain: A Randomized Clinical Trial
Abstract
1. Introduction
2. Materials and Methods
2.1. Setting
2.2. Participants
2.3. Sample Size
2.4. Interventions
2.5. Randomization and Blinding
2.6. Outcomes
2.7. Statistical Analyses
3. Results
3.1. Between-Group Differences in Shoulder Pain and Disability Outcomes
3.2. Between-Group Differences in Perceived Improvement, Satisfaction and Expectations with Received Treatment and Adherence to the Exercise Program
3.3. Web-Based Application Perceptions
4. Discussion
Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| CERT | Consensus on Exercise Reporting Template |
| NPRS | Numeric Pain Rating Scale |
| PGI-I | Patient Global Impression of Improvement |
| SPADI | Shoulder Pain and Disability Index |
| SUS | System Usability Scale |
| RCRSP | Rotator Cuff-Related Shoulder Pain |
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| Group | Control (n = 80) | Experimental (n = 74) | ||||
|---|---|---|---|---|---|---|
| Variable | N | Mean | SD | N | Mean | SD |
| Age, years | 80 | 55.3 | 11.1 | 74 | 54.6 | 12.9 |
| BMI | 80 | 26.9 | 4.5 | 72 | 26.4 | 4.4 |
| Sex, Male | 29 | 36.2% | 34 | 45.9% | ||
| Education | ||||||
| Primary | 26 | 32.5% | 25 | 33.8% | ||
| Secondary | 21 | 26.3% | 27 | 36.5% | ||
| No education | 1 | 1.3% | ||||
| University | 32 | 40.0% | 22 | 29.7% | ||
| Pain side | ||||||
| Left | 25 | 31.3% | 28 | 37.8% | ||
| Right | 55 | 68.8% | 46 | 62.2% | ||
| Pain side equal dominant side | 53 | 66.3% | 46 | 62.2% | ||
| Previous PT | 3 | 3.8% | 6 | 8.1% | ||
| Previous analgesic | 34 | 42.5% | 42 | 56.8% | ||
| Group | Time | n | Mean | SD | Median | P25 | P75 | Min. | Max. |
|---|---|---|---|---|---|---|---|---|---|
| NPRS, rest | |||||||||
| Control | Baseline | 80 | 3.23 | 2.70 | 3 | 0.75 | 5 | 0 | 9 |
| 6 wk | 73 | 2 | 2.37 | 1 | 0 | 3 | 0 | 8 | |
| 12 wk | 59 | 1.44 | 1.75 | 1 | 0 | 2 | 0 | 6 | |
| 24 wk | 63 | 1.46 | 2.22 | 1 | 0 | 2 | 0 | 10 | |
| Experimental | Baseline | 74 | 3.49 | 2.42 | 4 | 2 | 5 | 0 | 10 |
| 6 wk | 61 | 2.67 | 2.67 | 1 | 0 | 5 | 0 | 9 | |
| 12 wk | 61 | 2.15 | 2.40 | 1 | 0 | 3 | 0 | 9 | |
| 24 wk | 56 | 1.98 | 2.65 | 1 | 0 | 3 | 0 | 9 | |
| NPRS, movement | |||||||||
| Control | Baseline | 80 | 6.24 | 1.99 | 6 | 5 | 8 | 0 | 10 |
| 6 wk | 73 | 3.58 | 2.64 | 3 | 2 | 5 | 0 | 10 | |
| 12 wk | 59 | 2.95 | 2.30 | 3 | 1 | 4.5 | 0 | 9 | |
| 24 wk | 63 | 3.02 | 2.66 | 2 | 1 | 4.5 | 0 | 10 | |
| Experimental | Baseline | 74 | 6.65 | 2.15 | 7 | 5 | 8 | 0 | 10 |
| 6 wk | 61 | 4.15 | 2.48 | 4 | 3 | 6 | 0 | 9 | |
| 12 wk | 61 | 3.52 | 2.77 | 3 | 1 | 6 | 0 | 9 | |
| 24 wk | 56 | 2.86 | 3.15 | 2 | 0 | 5.25 | 0 | 10 | |
| NPRS, night | |||||||||
| Control | Baseline | 80 | 5.79 | 3.06 | 6 | 3 | 8 | 0 | 10 |
| 6 wk | 73 | 3.72 | 3.08 | 3 | 1 | 7 | 0 | 10 | |
| 12 wk | 59 | 2.95 | 2.57 | 2 | 1 | 5 | 0 | 8 | |
| 24 wk | 63 | 2.73 | 2.88 | 2 | 0 | 4 | 0 | 10 | |
| Experimental | Baseline | 74 | 6.26 | 2.77 | 7 | 5 | 8 | 0 | 10 |
| 6 wk | 61 | 4.23 | 3.07 | 4 | 2 | 7 | 0 | 10 | |
| 12 wk | 61 | 3.38 | 3.01 | 3 | 1 | 6 | 0 | 10 | |
| 24 wk | 56 | 2.77 | 3.11 | 1.5 | 0 | 5.25 | 0 | 9 | |
| SPADI | |||||||||
| Control | Baseline | 80 | 52.96 | 18.62 | 51.57 | 40.58 | 67.11 | 9.23 | 89.17 |
| 6 wk | 73 | 35.13 | 23.09 | 29.23 | 16.15 | 58.46 | 0 | 92.5 | |
| 12 wk | 59 | 27.84 | 20.10 | 27.69 | 10.39 | 43.59 | 0 | 86.92 | |
| 24 wk | 63 | 25.48 | 24.37 | 20.77 | 5.39 | 34.62 | 0 | 96.92 | |
| Experimental | Baseline | 74 | 55.58 | 18.99 | 59.23 | 43.65 | 68.08 | 16.92 | 90.78 |
| 6 wk | 61 | 38.08 | 24.29 | 36.15 | 16.15 | 61.67 | 0 | 84.62 | |
| 12 wk | 60 | 34.10 | 26.13 | 27.69 | 12.07 | 58.08 | 0 | 87.69 | |
| 24 wk | 56 | 27.73 | 27.47 | 18.08 | 3.66 | 47.69 | 0 | 90 | |
| Patient’s expectations | |||||||||
| Control | Baseline | 78 | 8.83 | 1.45 | 9 | 8 | 10 | 2 | 10 |
| 3 wk | 74 | 8.81 | 1.58 | 9 | 8 | 10 | 2 | 10 | |
| 6 wk | 69 | 8.54 | 1.93 | 9 | 8 | 10 | 2 | 10 | |
| Experimental | Baseline | 72 | 8.65 | 1.91 | 9 | 8 | 10 | 1 | 10 |
| 3 wk | 66 | 8.15 | 1.99 | 9 | 8 | 10 | 2 | 10 | |
| 6 wk | 59 | 8.19 | 2.51 | 9 | 8 | 10 | 0 | 10 | |
| Patient’s satisfaction | |||||||||
| Control | 6 wk | 69 | 7.91 | 1.96 | 8 | 7 | 9 | 2 | 10 |
| 24 wk | 53 | 7.89 | 1.94 | 8 | 7 | 10 | 3 | 10 | |
| Experimental | 6 wk | 59 | 7.76 | 2.35 | 8 | 7 | 10 | 0 | 10 |
| 24 wk | 51 | 7.80 | 2.32 | 9 | 6 | 10 | 1 | 10 | |
| Time | Original Dataset | Imputed Dataset | ||||
|---|---|---|---|---|---|---|
| Adjusted Between-Group Mean Difference * | Lower 95% CI | Upper 95% CI | Adjusted Between-Group Mean Difference * | Lower 95% CI | Upper 95% CI | |
| NPRS, rest | ||||||
| 6 wk | −0.49 | −1.25 | 0.27 | −0.47 | −1.25 | 0.31 |
| 12 wk | −0.17 | −0.95 | 0.61 | −0.29 | −1.02 | 0.45 |
| 24 wk | −0.37 | −1.18 | 0.43 | −0.38 | −1.23 | 0.46 |
| NPRS, movement | ||||||
| 6 wk | −0.46 | −1.35 | 0.43 | −0.32 | −1.18 | 0.54 |
| 12 wk | −0.17 | −1.08 | 0.74 | −0.18 | −1.04 | 0.67 |
| 24 wk | 0.30 | −0.64 | 1.23 | 0.16 | −0.84 | 1.15 |
| NPRS, night | ||||||
| 6 wk | −0.27 | −1.22 | 0.67 | −0.28 | −1.33 | 0.77 |
| 12 wk | 0.17 | −0.80 | 1.14 | 0.01 | −1.00 | 1.02 |
| 24 wk | 0.27 | −0.73 | 1.26 | 0.15 | −0.90 | 1.20 |
| SPADI | ||||||
| 6 wk | −0.74 | −8.25 | 6.77 | −0.86 | −8.48 | 6.76 |
| 12 wk | −1.54 | −9.22 | 6.14 | −1.72 | −8.84 | 5.41 |
| 24 wk | −0.29 | −8.16 | 7.57 | −0.54 | −9.02 | 7.93 |
| Patients’ expectations | ||||||
| 3 wk | 0.53 | −0.05 | 1.11 | 0.52 | −0.07 | 1.10 |
| 6 wk | 0.20 | −0.40 | 0.80 | 0.45 | −0.13 | 1.04 |
| Patients’ satisfaction with received treatment | ||||||
| 6 wk | 0.08 | −0.66 | 0.81 | 0.37 | −0.38 | 1.13 |
| 24 wk | −0.03 | −0.84 | 0.78 | −0.06 | −0.80 | 0.67 |
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Pérez-Porta, I.; García-Pérez, F.; Pérez-Manzanero, M.Á.; Urraca-Gesto, M.A.; Araujo-Narváez, A.; Velasco-Arribas, M.; Navarro-Santana, M.J.; Plaza-Manzano, G.; Pérez-Fernández, E.; Flórez-García, M.T. Adding Multimedia Animations to Exercise Therapy Provides No Additional Benefit for Rotator Cuff–Related Shoulder Pain: A Randomized Clinical Trial. J. Clin. Med. 2025, 14, 7964. https://doi.org/10.3390/jcm14227964
Pérez-Porta I, García-Pérez F, Pérez-Manzanero MÁ, Urraca-Gesto MA, Araujo-Narváez A, Velasco-Arribas M, Navarro-Santana MJ, Plaza-Manzano G, Pérez-Fernández E, Flórez-García MT. Adding Multimedia Animations to Exercise Therapy Provides No Additional Benefit for Rotator Cuff–Related Shoulder Pain: A Randomized Clinical Trial. Journal of Clinical Medicine. 2025; 14(22):7964. https://doi.org/10.3390/jcm14227964
Chicago/Turabian StylePérez-Porta, Irene, Fernando García-Pérez, María Ángeles Pérez-Manzanero, María Alicia Urraca-Gesto, Aurora Araujo-Narváez, María Velasco-Arribas, Marcos José Navarro-Santana, Gustavo Plaza-Manzano, Elia Pérez-Fernández, and Mariano Tomás Flórez-García. 2025. "Adding Multimedia Animations to Exercise Therapy Provides No Additional Benefit for Rotator Cuff–Related Shoulder Pain: A Randomized Clinical Trial" Journal of Clinical Medicine 14, no. 22: 7964. https://doi.org/10.3390/jcm14227964
APA StylePérez-Porta, I., García-Pérez, F., Pérez-Manzanero, M. Á., Urraca-Gesto, M. A., Araujo-Narváez, A., Velasco-Arribas, M., Navarro-Santana, M. J., Plaza-Manzano, G., Pérez-Fernández, E., & Flórez-García, M. T. (2025). Adding Multimedia Animations to Exercise Therapy Provides No Additional Benefit for Rotator Cuff–Related Shoulder Pain: A Randomized Clinical Trial. Journal of Clinical Medicine, 14(22), 7964. https://doi.org/10.3390/jcm14227964

