Anophthalmic Sockets: A Retrospective Review of Enucleations, Eviscerations, and Exenterations Performed and Managed in a Tertiary Care Hospital
Abstract
1. Introduction
2. Materials and Methods
3. Results
Primary Sockets
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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| All Procedures (n = 170) | Enucleation (n = 120) | Evisceration (n = 13) | ||||
|---|---|---|---|---|---|---|
| Condition | Primary Procedure (n = 82) (%) | Secondary Socket Management (n = 88) (%) | Primary Procedure (n = 70) (%) | Secondary Socket Management (n = 50) (%) | Primary Procedure (n = 7) (%) | Secondary Socket Management (n = 6) (%) |
| Ocular/Orbital Tumor | 41 (50.0) | 31 (35.2) | 36 (51.4) | 25 (50.0) | 0 (0.0) | 2 (33.3) |
| Trauma | 14 (17.1) | 31 (35.2) | 14 (20.0) | 15 (30.0) | 0 (0.0) | 2 (33.3) |
| Fulminating infections | 12 (14.6) | 8 (9.1) | 5 (7.14) | 1 (2.0) | 7 (100.0) | 1 (16.7) |
| Congenital anomalies | 5 (6.1) | 9 (10.2) | 5 (7.14) | 2 (4.0) | 0 (0.0) | 0 (0.0) |
| Rubeotic glaucoma | 6 (7.3) | 2 (2.3) | 6 (8.57) | 1 (2.0) | 0 (0.0) | 1 (16.7) |
| Failed retinal detachment surgery | 4 (4.9) | 1 (1.1) | 4 (5.71) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Others | 0 (0.0) | 10 (11.4) | 0 (0.0) | 6 (12.0) | 0 (0.0) | 0 (0.0) |
| Demographics | n (%) |
|---|---|
| Gender | |
| Male | 45 (54.9) |
| Female | 37 (45.1) |
| Nationality | |
| Singaporean | 44 (53.7) |
| Indonesian | 15 (18.3) |
| Vietnamese | 7 (8.5) |
| Indian | 5 (6.1) |
| Malaysian | 5 (6.1) |
| Others (East Timorese | 6 (7.3) |
| Bruneian, Burmese, Malaysian) | |
| Mean Age | 34.1 ± 30.0 years |
| Enucleation Evisceration Exenteration | 70 (85.4) 7 (8.5) 5 (6.1) |
| Mean follow-up period | 3.1 ± 3.4 years |
| Implant Characteristics | n (%) |
|---|---|
| Implant shapes for sockets that underwent primary procedure (n = 75) | |
| Spherical | 72 (96.0) |
| Conical | 2 (2.67) |
| Quadraspheric | 1 (1.33) |
| Materials used for the wrapped implants (n = 59) | |
| Donor sclera | 31 (52.5) |
| Bovine pericardium (Tutopatch® (LifeCell Corporation, New Jersey, USA)) | 27 (45.8) |
| Acellular dermal matrix (AlloDermTM (Tutogen Medical GmbH, Neunkirchen am Brand, Germany)) | 1 (1.69) |
| Complications | Description |
|---|---|
| Mild | Discomfort, pain, inflammation, edema etc. |
| Moderate | Conjunctival prolapse, wound dehiscence, delayed recovery, ptosis, mild enophthalmos, etc. |
| Severe | Incomplete globe removal, implant extrusion, exposure, severe contracted sockets, severe infections, revision surgery, etc. |
| Demographics | n (%) |
|---|---|
| Gender | |
| Male | 42 (47.7) |
| Female | 46 (52.3) |
| Nationality | |
| Singaporean | 49 (55.7) |
| Indonesian | 14 (15.9) |
| Others (Philippines, Russian, Burmese, Sri Lankan, Cebu, Chinese, German) | 7 (8.0) |
| Malaysian | |
| Bangladeshi | 6 (6.8) |
| Vietnamese | 3 (3.4) |
| Bruneian | 3 (3.4) |
| Indian | 3 (3.4) |
| Mean Age | 38.3 ± 24.7 years |
| Primary Procedure Performed | |
| Enucleation | 50 (56.8) |
| Unknown | 23 (26.1) |
| Evisceration | 6 (6.8) |
| Congenital anophthalmia | 8 (9.1) |
| Exenteration | 1 (1.1) |
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Wei, D.Y.W.; Pan, J.T.; Ming, S.Y.; Sundar, G. Anophthalmic Sockets: A Retrospective Review of Enucleations, Eviscerations, and Exenterations Performed and Managed in a Tertiary Care Hospital. J. Clin. Med. 2025, 14, 7764. https://doi.org/10.3390/jcm14217764
Wei DYW, Pan JT, Ming SY, Sundar G. Anophthalmic Sockets: A Retrospective Review of Enucleations, Eviscerations, and Exenterations Performed and Managed in a Tertiary Care Hospital. Journal of Clinical Medicine. 2025; 14(21):7764. https://doi.org/10.3390/jcm14217764
Chicago/Turabian StyleWei, Dayna Yong Wei, Jason Timothy Pan, Stephanie Young Ming, and Gangadhara Sundar. 2025. "Anophthalmic Sockets: A Retrospective Review of Enucleations, Eviscerations, and Exenterations Performed and Managed in a Tertiary Care Hospital" Journal of Clinical Medicine 14, no. 21: 7764. https://doi.org/10.3390/jcm14217764
APA StyleWei, D. Y. W., Pan, J. T., Ming, S. Y., & Sundar, G. (2025). Anophthalmic Sockets: A Retrospective Review of Enucleations, Eviscerations, and Exenterations Performed and Managed in a Tertiary Care Hospital. Journal of Clinical Medicine, 14(21), 7764. https://doi.org/10.3390/jcm14217764

