Patient Race Independently Predicts Timeliness of Breast Cancer Reconstructive Care
Abstract
1. Introduction
2. Materials and Methods
2.1. Ethical Review
2.2. Study Design and Inclusion/Exclusion Criteria
2.3. Patient Data Collection
2.4. Statistical Analyses
3. Results
3.1. Baseline Characteristics
3.2. Univariable Linear Regression Analysis
3.3. Multivariable Linear Regression Analysis
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
PRS | Plastic and Reconstructive Surgery |
CAD | Coronary Artery Disease |
HTN | Hypertension |
HLD | Hyperlipidemia |
MI | Myocardial Infarction |
PAD | Peripheral Artery Disease |
CVA | Cerebrovascular Accidents |
HF | Heart Failure |
COPD | Chronic Obstructive Pulmonary Disease |
ABR | Autologous Breast Reconstruction |
IBR | Implant-Based Reconstruction |
SD | Standard Deviation |
CI | Confidence Interval |
References
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White | Black | Asian | Other | Unknown | p-Value | |
---|---|---|---|---|---|---|
n = 745 | n = 337 | n = 199 | n = 278 | n = 103 | ||
Age | 53 (12) | 54 (11) | 48 (10) | 53 (11) | 52 (11) | <0.001 |
BMI | 26.8 (7.9) | 30.2 (5.8) | 24.6 (4.3) | 28.7 (5.4) | 28.3 (5.3) | <0.001 |
Ethnicity | <0.001 | |||||
Latino | 16 (2.1%) | 6 (1.8%) | 1 (0.5%) | 138 (50%) | 77 (75%) | |
Non-Latino | 723 (97%) | 331 (98%) | 198 (99%) | 130 (47%) | 23 (22%) | |
Comorbidities | ||||||
CAD | 24 (3.2%) | 20 (5.9%) | 2 (1.0%) | 10 (3.6%) | 3 (2.9%) | 0.0454 |
MI | 4 (0.5%) | 5 (1.5%) | 1 (0.5%) | 2 (0.7%) | 1 (1.0%) | 0.4944 |
Heart Failure | 42 (5.6%) | 34 (10%) | 12 (6.0%) | 18 (6.5%) | 15 (15%) | 0.0033 |
PAD | 19 (2.6%) | 16 (4.7%) | 2 (1.0%) | 14 (5.0%) | 5 (4.9%) | 0.0284 |
CVA | 14 (1.9%) | 13 (3.9%) | 3 (1.5%) | 5 (1.8%) | 4 (3.9%) | 0.1984 |
Diabetes | 33 (4.4%) | 40 (12%) | 11 (5.5%) | 45 (16%) | 11 (11%) | <0.001 |
HTN | 167 (22%) | 148 (44%) | 33 (17%) | 98 (35%) | 28 (27%) | <0.001 |
HLD | 116 (16%) | 83 (25%) | 28 (14%) | 72 (26%) | 18 (17%) | <0.001 |
Asthma | 64 (8.6%) | 43 (13%) | 7 (3.5%) | 41 (15%) | 13 (13%) | <0.001 |
COPD | 20 (2.7%) | 9 (2.7%) | 0 (0%) | 7 (2.5%) | 2 (1.9%) | 0.1144 |
Liver Disease | 37 (5.0%) | 25 (7.4%) | 20 (10%) | 15 (5.4%) | 7 (6.8%) | 0.0863 |
Renal History | 7 (0.9%) | 20 (6.0%) | 3 (1.5%) | 8 (2.9%) | 2 (1.9%) | <0.001 |
Reconstruction Type | <0.001 | |||||
Immediate Implant | 58 (7.8%) | 16 (4.7%) | 8 (4.0%) | 15 (5.4%) | 1 (1.0%) | |
Delayed Implant | 349 (47%) | 96 (28%) | 64 (32%) | 106 (38%) | 6 (5.8%) | |
Immediate Autologous | 270 (36%) | 172 (51%) | 112 (56%) | 119 (43%) | 82 (80%) | |
Delayed Autologous | 44 (5.9%) | 37 (11%) | 11 (5.5%) | 31 (11%) | 13 (13%) | |
Other | 24 (3.2%) | 16 (4.7%) | 4 (2.0%) | 7 (2.5%) | 1 (1.0%) | |
Laterality | <0.001 | |||||
Unilateral | 251 (34%) | 181 (54%) | 118 (59%) | 137 (49%) | 53 (51%) | |
Bilateral | 494 (66%) | 156 (46%) | 81 (41%) | 141 (51%) | 50 (49%) | |
Insurance | <0.001 | |||||
Medicare | 157 (21%) | 103 (31%) | 21 (11%) | 71 (26%) | 15 (15%) | |
Medicaid | 76 (10%) | 59 (18%) | 49 (25%) | 81 (29%) | 30 (29%) | |
Private | 503 (68%) | 175 (52%) | 125 (63%) | 126 (45%) | 56 (54%) | |
Procedure Time | ||||||
Index Procedure | 5.06 (2.54) | 5.60 (2.94) | 5.42 (2.98) | 5.55 (2.84) | 7.18 (2.70) | <0.001 |
Aggregate Procedures | 6.16 (2.47) | 6.57 (2.95) | 6.31 (3.00) | 6.77 (2.71) | 7.94 (2.65) | <0.001 |
Clinical Timelines | ||||||
Diagnosis to PRS consult | 80 (233) | 94 (176) | 346 (3243) | 110 (267) | 85 (132) | <0.001 |
Diagnosis to Index Procedure | 261 (2447) | 150 (210) | 382 (3174) | 160 (296) | 138 (153) | <0.001 |
Diagnosis to Final Procedure | 390 (2528) | 280 (372) | 473 (3209) | 289 (449) | 224 (353) | 0.0172 |
Diagnosis to PRS Consult | Diagnosis to Index Procedure | Diagnosis to Final Procedure | ||||
---|---|---|---|---|---|---|
Beta (95% CI) 1 | p-Value | Beta (95% CI) 1 | p-Value | Beta (95% CI) 1 | p-Value | |
Overall | ||||||
Black | 0.339 (0.162 to 0.516) | <0.001 | 0.302 (0.168 to 0.435) | <0.001 | 0.083 (−0.073 to 0.239) | 0.3 |
Asian | 0.300 (0.083 to 0.517) | 0.007 | 0.164 (0.001 to 0.326) | 0.049 | −0.033 (−0.219 to 0.153) | 0.73 |
Other | 0.380 (0.188 to 0.571) | <0.001 | 0.308 (0.164 to 0.451) | <0.001 | 0.172 (0.005 to 0.339) | 0.044 |
Unknown | 0.296 (0.011 to 0.582) | 0.042 | 0.297 (0.080 to 0.514) | 0.007 | −0.192 (−0.436 to 0.051) | 0.12 |
ABR Cohort | ||||||
Black | 0.238 (0.009 to 0.468) | 0.042 | 0.142 (−0.031 to 0.315) | 0.11 | 0.201 (−0.002 to 0.405) | 0.053 |
Asian | 0.320 (0.041 to 0.599) | 0.025 | 0.117 (−0.092 to 0.326) | 0.27 | 0.042 (−0.204 to 0.288) | 0.74 |
Other | 0.245 (−0.020 to 0.510) | 0.07 | 0.197 (0.003 to 0.392) | 0.047 | 0.206 (−0.023 to 0.435) | 0.078 |
Unknown | 0.261 (−0.042 to 0.565) | 0.091 | 0.213 (−0.016 to 0.442) | 0.068 | 0.185 (−0.082 to 0.452) | 0.17 |
IBR Cohort | ||||||
Black | 0.537 (0.242 to 0.831) | <0.001 | 0.516 (0.298 to 0.734) | <0.001 | 0.342 (0.119 to 0.565) | 0.003 |
Asian | 0.259 (−0.088 to 0.607) | 0.14 | 0.192 (−0.067 to 0.451) | 0.15 | 0.150 (−0.095 to 0.396) | 0.23 |
Other | 0.505 (0.226 to 0.785) | <0.001 | 0.391 (0.180 to 0.603) | <0.001 | 0.254 (0.046 to 0.462) | 0.017 |
Unknown | 0.178 (−1.071 to 1.426) | 0.78 | 0.243 (−0.725 to 1.211) | 0.62 | 0.097 (−0.792 to 0.987) | 0.83 |
Diagnosis to PRS Consult | Diagnosis to Index Procedure | Diagnosis to Final Procedure | ||||
---|---|---|---|---|---|---|
Beta (95% CI) 1 | p-Value | Beta (95% CI) 1 | p-Value | Beta (95% CI) 1 | p-Value | |
Overall | ||||||
Black | 0.307 (0.121 to 0.493) | 0.001 | 0.254 (0.117 to 0.390) | <0.001 | 0.213 (0.084 to 0.342) | 0.001 |
Asian | 0.267 (0.042 to 0.491) | 0.02 | 0.157 (−0.008 to 0.321) | 0.062 | 0.091 (−0.061 to 0.243) | 0.24 |
Other | 0.332 (0.095 to 0.568) | 0.006 | 0.283 (0.111 to 0.456) | 0.001 | 0.120 (−0.043 to 0.283) | 0.15 |
Unknown | 0.276 (−0.082 to 0.634) | 0.13 | 0.277 (0.011 to 0.544) | 0.042 | 0.147 (−0.098 to 0.391) | 0.24 |
ABR Cohort | ||||||
Black | 0.256 (0.015 to 0.496) | 0.037 | 0.149 (−0.026 to 0.324) | 0.1 | 0.155 (−0.019 to 0.328) | 0.08 |
Asian | 0.299 (0.005 to 0.593) | 0.046 | 0.152 (−0.061 to 0.364) | 0.16 | 0.128 (−0.082 to 0.337) | 0.23 |
Other | 0.194 (−0.118 to 0.506) | 0.22 | 0.153 (−0.067 to 0.373) | 0.17 | 0.047 (−0.171 to 0.264) | 0.68 |
Unknown | 0.237 (−0.175 to 0.650) | 0.26 | 0.197 (−0.102 to 0.496) | 0.2 | 0.130 (−0.161 to 0.421) | 0.38 |
IBR Cohort | ||||||
Black | 0.459 (0.148 to 0.770) | 0.004 | 0.447 (0.218 to 0.675) | <0.001 | 0.322 (0.120 to 0.523) | 0.002 |
Asian | 0.224 (−0.130 to 0.578) | 0.21 | 0.172 (−0.091 to 0.436) | 0.2 | 0.044 (−0.174 to 0.263) | 0.69 |
Other | 0.521 (0.141 to 0.900) | 0.007 | 0.411 (0.124 to 0.698) | 0.005 | 0.155 (−0.099 to 0.410) | 0.23 |
Unknown | 0.186 (−1.121 to 1.494) | 0.78 | 0.233 (−0.779 to 1.245) | 0.65 | −0.139 (−0.959 to 0.681) | 0.74 |
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Roth, J.; Yu, B.Z.; Godek, M.; Fung, E.; Barrow, B.; Taub, P.J.; Henderson, P.W. Patient Race Independently Predicts Timeliness of Breast Cancer Reconstructive Care. J. Clin. Med. 2025, 14, 6532. https://doi.org/10.3390/jcm14186532
Roth J, Yu BZ, Godek M, Fung E, Barrow B, Taub PJ, Henderson PW. Patient Race Independently Predicts Timeliness of Breast Cancer Reconstructive Care. Journal of Clinical Medicine. 2025; 14(18):6532. https://doi.org/10.3390/jcm14186532
Chicago/Turabian StyleRoth, Jacquelyn, Bernice Z. Yu, Maxwell Godek, Ethan Fung, Brooke Barrow, Peter J. Taub, and Peter W. Henderson. 2025. "Patient Race Independently Predicts Timeliness of Breast Cancer Reconstructive Care" Journal of Clinical Medicine 14, no. 18: 6532. https://doi.org/10.3390/jcm14186532
APA StyleRoth, J., Yu, B. Z., Godek, M., Fung, E., Barrow, B., Taub, P. J., & Henderson, P. W. (2025). Patient Race Independently Predicts Timeliness of Breast Cancer Reconstructive Care. Journal of Clinical Medicine, 14(18), 6532. https://doi.org/10.3390/jcm14186532