Return to Work After Work-Related Injuries: A Systematic Review and Meta-Analysis of Incidence and Determinants
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Search Strategy
2.3. Eligibility Criteria
2.4. Screening Process
2.5. Data Extraction
2.6. Risk of Bias Assessment
2.7. Statistical Analysis
2.8. Ethical Considerations
3. Results
3.1. Risk of Bias Assessment
3.2. Outcomes
3.2.1. Incidence of RTW
3.2.2. Meta-Regression
3.2.3. Time to Return to Work
3.2.4. Predictors of RTW
4. Discussion
4.1. Incidence and Timing of RTW
4.2. Influence of Age
4.3. Sex Differences
4.4. Marital Status and Education
4.5. Impact of Injury Type
4.6. Strengths and Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
CI | Confidence Interval |
PRISMA | Preferred Reporting Items for Systematic Reviews and Meta-Analyses |
RTW | Return to Work |
References
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Study ID | Study Design | Country | Injury Site | Treatment | Period of Data Collection | Age Means (SD) | Sex M/F |
---|---|---|---|---|---|---|---|
Skov et al., 1999 [8] | Retrospective cohort | Denmark | Hand injury | Surgical, clinical, and rehabilitation | - | ||
Tamene et al., 2022 [9] | Retrospective cohort | Ethiopia | Spine (29.6%), the upper limbs (34.1%), head and neck (21.1%), and the lower limbs (15.2%). | Surgical, clinical, and rehabilitation | Between 1 January 2017, and 31 December 2021 | 30 (4.5) | 398/24 |
Hosseininejad et al., 2023 [19] | Retrospective cohort | Iran | Upper limb injuries | Physiotherapy and prosthesis use | March 2011 to December 2018 | 34.10 ± 9.04 | 245/11 |
Chen et al., 2012 [20] | Prospective cohort | Taiwan | Hand injury | Surgical, clinical, and rehabilitation | - | 35 (6.7) | 92/28 |
Chang et al., 2011 [21] | Retrospective cohort | Taiwan | Traumatic hand injury | - | From 2003 to 2006 | 40.2 (12.5) | 80/16 |
Molen et al., 1999 [22] | Prospective cohort | USA | Hand injury | - | - | - | - |
Wong, 2008 [23] | Prospective cohort | China | Hand Injury | Surgical reconstruction | - | 40 (12) | 100/24 |
Matsuzaki, 2009 [24] | Retrospective cohort | Japan | Hand Injury | Surgical, clinical, and rehabilitation | Between October 1990 and August 2003 | 43 (18–69) | 40/10 |
Journeay et al., 2018 [25] | Retrospective cohort | Canada | Lower extremity | Surgical amputation | - | 41.7 (15) | 19/0 |
Yang et al., 2022 [26] | Retrospective Cohort | Taiwan | The upper limbs (61.9%), the lower limbs (13.1%), others (25%) | - | September 2016 and December 2018 | 41.24 ± 12.33 | 54/30 |
Lee et al., 2010 [27] | Retrospective cohort | Taiwan | Hand injury | Surgical, clinical, and rehabilitation | Between September and November 2008 | 42.6 (12.9) | 99/41 |
Schroeder et al., 2020 [28] | Retrospective cohort | Canada | Upper limb injuries | Physiotherapy, pain treatment, surgery, psychological treatment | Between April 2011 and September 2015 | 46 (11) | 570/298 |
Üstün et al., 2022 [29] | Retrospective cohort | Turkey | Hand injury | Surgical, clinical, and rehabilitation | Between April 2020 and October 2021 | 43.6 | 99/12 |
Izadi et al., 2020 [30] | Prospective cohort | Iran | Hand injury | - | Between July 2017 and February 2018 | 34.26 (9.67) | 271/8 |
Chu et al., 2019 [31] | Prospective cohort | Taiwan | - | Physiotherapy, pain treatment, pharmacist assessment, surgery, psychology | Between 1 February and 31 August 2009. | 47.8 (11.1) | 386/186 |
Du et al., 2007 [32] | Retrospective cohort | Taiwan | Upper limb injuries | Surgical, clinical, and rehabilitation | 16 August to 15 October 2003 | 40.3 ± 9.8 | 91/19 |
Study | Population Defined | Exposure Measured | Outcome Measured | Confounding Controlled | Follow-Up Adequate | Overall Rating |
---|---|---|---|---|---|---|
Skov et al., 1999 [8] | Yes | Yes | Yes | No | Yes | High |
Tamene et al., 2022 [9] | Yes | Yes | Yes | Yes | Yes | High |
Hosseininejad et al., 2023 [19] | Yes | Yes | Yes | Yes | Yes | Moderate |
Chen et al., 2012 [20] | Yes | Yes | Yes | Yes | Yes | Moderate |
Chang et al., 2011 [21] | Yes | Yes | Yes | Yes | Yes | Moderate |
Molen et al., 1999 [22] | Yes | Yes | Yes | No | No | Low |
Wong, 2008 [23] | Yes | Yes | Yes | Yes | Yes | Moderate |
Matsuzaki, 2009 [24] | Yes | Yes | Yes | Yes | Yes | High |
Journeay et al., 2018 [25] | Yes | Yes | Yes | Yes | Yes | High |
Yang et al., 2022 [26] | Yes | Yes | Yes | Yes | Yes | Moderate |
Lee et al., 2010 [27] | Yes | Yes | Yes | Yes | Yes | High |
Schroeder et al., 2020 [28] | Yes | Yes | Yes | Yes | Yes | High |
Üstün et al., 2022 [29] | Yes | Yes | Yes | Yes | Yes | High |
Izadi et al., 2020 [30] | Yes | Yes | Yes | Yes | Yes | Moderate |
Chu et al., 2019 [31] | Yes | Yes | Yes | Yes | Yes | Moderate |
Du et al., 2007 [32] | Yes | Yes | Yes | No | No | Low |
Predictor | Comparison | Included Studies | Risk Ratio (RR) | 95% Confidence Interval | p-Value | I2 (%) | Model | Interpretation |
---|---|---|---|---|---|---|---|---|
Sex | Male vs. Female | Chang et al., 2011 [21], Du et al., 2007 [32], Hosseininejad et al., 2023 [19], Izadi et al., 2020 [30], Lee et al., 2010 [27], Schroeder et al., 2020 [28], Tamene, 2022 [9], and Yang et al., 2022 [26] | 6.12 | 2.33–16.06 | <0.0001 | 95.8 | Random-effects | Males had significantly higher RTW rates. |
Sex subgrouping | Subgroup: Before 2015 | Chang et al., 2011 [21], Du et al., 2007 [32], and Lee et al., 2010 [27] | 4.25 | 1.38–13.05 | 0.0193 | 74.7 | Random-effects | Moderate heterogeneity in older studies, with no change in the context of results |
Subgroup: 2015 and after | Hosseininejad et al., 2023 [19], Izadi et al., 2020 [30], Schroeder et al., 2020 [28], Tamene, 2022 [9], and Yang et al., 2022 [26] | 7.95 | 1.29–49.00 | <0.0001 | 97.2 | Random-effects | Very high heterogeneity in recent studies, with no change in the context of results | |
Subgroup difference test | — | — | 0.3750 | — | — | No statistically significant subgroup difference (χ2 = 0.79, df = 1) | ||
Marital Status | Married vs. Single | Hosseininejad et al., 2023 [19], Du et al., 2007 [32], Lee et al., 2010 [27], and Yang et al., 2022 [26] | 0.43 | 0.18–1.02 | <0.0001 | 88.3 | Random-effects | Married workers showed higher RTW |
Marital Status (SA *) | Married vs. Single (SA) | Sensitivity analysis excluding Hosseininejad et al. [19] | 0.55 | 0.30–1.01 | 0.1563 | 46.1% | Random-effects | There was no difference between the two groups in terms of RTW incidence. |
Education | >Grade 12 vs. ≤Grade 12 | Hosseininejad et al., 2023 [19], Tamene, 2022 [9], Lee et al., 2010 [27], and Yang et al., 2022 [26] | 0.54 | 0.34–0.87 | 0.0033 | 78.1 | Random-effects | Higher education is linked to more RTW. |
Education (SA *) | >Grade 12 vs. ≤Grade 12 | Sensitivity analysis excluding Tamene et al. [9] | 0.47 | 0.29–0.77 | 0.2562 | 26.6 | Random-effects | There was no difference between the two groups in terms of RTW incidence. |
Injury | Laceration vs. Crushing | Üstün et al., 2022 [29], Du et al., 2007 [32], and Wong, 2008 [23] | 1.89 | 0.11–33.74 | <0.0001 | 91.6 | Random-effects | Workers with lacerations had higher RTW |
Injury (SA *) | Laceration vs. Crushing | Sensitivity analysis excluding Du et al. [32] | 3.99 | 0.20–80.10 | 0.2667 | 19.3 | Random-effects | There was no difference between the two groups in terms of RTW incidence. |
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Santos, W.; Rojas, C.; Isidoro, R.; Lorente, A.; Dias, A.; Mariscal, G.; Zabady, A.H.; Lorente, R. Return to Work After Work-Related Injuries: A Systematic Review and Meta-Analysis of Incidence and Determinants. J. Clin. Med. 2025, 14, 4343. https://doi.org/10.3390/jcm14124343
Santos W, Rojas C, Isidoro R, Lorente A, Dias A, Mariscal G, Zabady AH, Lorente R. Return to Work After Work-Related Injuries: A Systematic Review and Meta-Analysis of Incidence and Determinants. Journal of Clinical Medicine. 2025; 14(12):4343. https://doi.org/10.3390/jcm14124343
Chicago/Turabian StyleSantos, Weiner, Carmen Rojas, Rui Isidoro, Alejandro Lorente, Ana Dias, Gonzalo Mariscal, Ahmed Hamdy Zabady, and Rafael Lorente. 2025. "Return to Work After Work-Related Injuries: A Systematic Review and Meta-Analysis of Incidence and Determinants" Journal of Clinical Medicine 14, no. 12: 4343. https://doi.org/10.3390/jcm14124343
APA StyleSantos, W., Rojas, C., Isidoro, R., Lorente, A., Dias, A., Mariscal, G., Zabady, A. H., & Lorente, R. (2025). Return to Work After Work-Related Injuries: A Systematic Review and Meta-Analysis of Incidence and Determinants. Journal of Clinical Medicine, 14(12), 4343. https://doi.org/10.3390/jcm14124343