Next Article in Journal
Frailty and Medication Appropriateness in Rural Adults: Proposing Interventions through Pharmacist–Physician Collaborative Efforts
Previous Article in Journal
Comparison of Efficacy of Micropulse Laser Settings for Glaucoma Management
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 13
Issue 19
10.3390/jcm13195754
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Pre- and Procedural Factors Influencing the Success of In Vitro Fertilization: Evaluating Embryo Quality and Clinical Pregnancy in Cases of Tubal Factor Infertility

by
Zoltan Kozinszky
1,2,*,†,
Kristóf Bereczki
2,†,
Viktor Vedelek
3,
Petra Bicskei
4,
Mariann Tabi
4,
Csaba Ekes
4,
Noémi Lajkó
4,
Olga Nagy
2,
Rita Sinka
3,
Anna Vágvölgyi
5,‡ and
János Zádori
4,‡
1
Capio Specialized Center for Gynecology, Solna, 182 88 Stockholm, Sweden
2
Department of Obstetrics and Gynecology, Albert Szent-Gyorgyi Medical School, University of Szeged, 6725 Szeged, Hungary
3
Department of Genetics, Faculty of Science and Informatics, University of Szeged, 6726 Szeged, Hungary
4
Institute of Reproductive Medicine, Albert Szent-Gyorgyi Medical School, University of Szeged, 6723 Szeged, Hungary
5
Department of Internal Medicine, Albert Szent-Gyorgyi Medical School, University of Szeged, 6725 Szeged, Hungary
*
Author to whom correspondence should be addressed.
†
Authors contributed equally as first authors.
‡
Authors contributed equally as last authors.
J. Clin. Med. 2024, 13(19), 5754; https://doi.org/10.3390/jcm13195754
Submission received: 30 August 2024 / Revised: 23 September 2024 / Accepted: 25 September 2024 / Published: 27 September 2024
(This article belongs to the Section Obstetrics & Gynecology)
Browse Figure
Versions Notes

Abstract

Introduction: While tubal occlusion is a prevalent cause of infertility, accounting for 11–35% of infertility cases among women, there remains a limited understanding of the factors influencing clinical pregnancy following in vitro fertilization (IVF). Methods: In our retrospective, cross-sectional cohort study conducted at a single tertiary center, medical records of women aged 19 to 43 years were analyzed. Logistic regression models were employed to identify the prognostic factors associated with clinical pregnancy after IVF in patients with tubal factor infertility, excluding cases with hydrosalpinx. Results: Data from 219 women diagnosed with tubal occlusion were compared to 1140 cases with non-tubal indication, covering a total of 1359 IVF cycles. A lower maternal age (adjusted odds ratio [AOR]: 0.89, p = 0.001) and a higher embryo quality (AOR: 1.26, p = 0.01) emerged as important factors in clinical pregnancy in the tubal infertility group. Moreover, a lower maternal (AOR:0.91, p < 0.01) and paternal age (p = 0.001), and favorable semen quality (AOR: 1.32, p = 0.03) were critical determinants in the non-tubal infertility group. BMI was generally higher in tubal infertility patients (p = 0.01). Furthermore, FSH level (AOR: 0.93, p = 0.004), AMH level (p < 0.04), number of embryos transferred (AOR: 2.04, p < 0.001), and embryo quality (AOR: 1.26, p < 0.001) came into prominence only in the non-tubal infertility group. The clinical pregnancy rate (34.2%) of women with tubal occlusion did not differ significantly from those in other forms of infertility undergoing IVF (35.4%). Conclusions: Although tubal infertility is typically anticipated to yield the highest clinical pregnancy rates following IVF, it is crucial to acknowledge that both maternal and paternal characteristics can also significantly impact the outcomes.
Keywords: in vitro fertilization; clinical pregnancy; fallopian tube blockage; non-tubal factor infertility in vitro fertilization; clinical pregnancy; fallopian tube blockage; non-tubal factor infertility

Share and Cite

MDPI and ACS Style

Kozinszky, Z.; Bereczki, K.; Vedelek, V.; Bicskei, P.; Tabi, M.; Ekes, C.; Lajkó, N.; Nagy, O.; Sinka, R.; Vágvölgyi, A.; et al. Pre- and Procedural Factors Influencing the Success of In Vitro Fertilization: Evaluating Embryo Quality and Clinical Pregnancy in Cases of Tubal Factor Infertility. J. Clin. Med. 2024, 13, 5754. https://doi.org/10.3390/jcm13195754

AMA Style

Kozinszky Z, Bereczki K, Vedelek V, Bicskei P, Tabi M, Ekes C, Lajkó N, Nagy O, Sinka R, Vágvölgyi A, et al. Pre- and Procedural Factors Influencing the Success of In Vitro Fertilization: Evaluating Embryo Quality and Clinical Pregnancy in Cases of Tubal Factor Infertility. Journal of Clinical Medicine. 2024; 13(19):5754. https://doi.org/10.3390/jcm13195754

Chicago/Turabian Style

Kozinszky, Zoltan, Kristóf Bereczki, Viktor Vedelek, Petra Bicskei, Mariann Tabi, Csaba Ekes, Noémi Lajkó, Olga Nagy, Rita Sinka, Anna Vágvölgyi, and et al. 2024. "Pre- and Procedural Factors Influencing the Success of In Vitro Fertilization: Evaluating Embryo Quality and Clinical Pregnancy in Cases of Tubal Factor Infertility" Journal of Clinical Medicine 13, no. 19: 5754. https://doi.org/10.3390/jcm13195754

APA Style

Kozinszky, Z., Bereczki, K., Vedelek, V., Bicskei, P., Tabi, M., Ekes, C., Lajkó, N., Nagy, O., Sinka, R., Vágvölgyi, A., & Zádori, J. (2024). Pre- and Procedural Factors Influencing the Success of In Vitro Fertilization: Evaluating Embryo Quality and Clinical Pregnancy in Cases of Tubal Factor Infertility. Journal of Clinical Medicine, 13(19), 5754. https://doi.org/10.3390/jcm13195754

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop