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Review

Endometriosis and Adenomyosis: Modern Concepts of Their Clinical Outcomes, Treatment, and Management

by
Jessica Ottolina
1,*,
Roberta Villanacci
1,
Sara D’Alessandro
1,
Xuemin He
2,
Giorgia Grisafi
1,
Stefano Maria Ferrari
1 and
Massimo Candiani
1
1
IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
2
Obstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of “Aldo Moro”, 70124 Bari, Italy
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(14), 3996; https://doi.org/10.3390/jcm13143996
Submission received: 10 April 2024 / Revised: 17 June 2024 / Accepted: 19 June 2024 / Published: 9 July 2024
(This article belongs to the Special Issue Endometriosis and Adenomyosis: Modern Concepts on Clinical Outcomes, Treatment and Management)
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Abstract

Endometriosis and adenomyosis are complex gynecological conditions characterized by diverse clinical presentations, including superficial peritoneal endometriosis (SPE), ovarian endometrioma (OMA), and deep infiltrating endometriosis (DIE). The hallmark features of these pathologies involve the manifestation of pain symptoms and infertility, and approximately 30% of patients are asymptomatic. Despite ongoing research, definitive treatments for these conditions remain elusive, and clinical management primarily revolves around medical or surgical interventions. Recent advancements in our understanding of the efficacy of various treatment modalities, including medical therapy and surgical interventions, have provided clinicians with valuable insights into pain relief and fertility preservation. This review aims to provide an updated overview of the latest literature on clinical outcomes, treatment options, and management strategies for different types of endometriosis. By synthesizing the newest available data, this review seeks to inform clinicians and guide decision making based on factors such as patients’ symptom severity, childbearing desire, and overall health.
Keywords: endometriosis; superficial peritoneal endometriosis; ovarian endometriosis; deep infiltrating endometriosis; adenomyosis endometriosis; superficial peritoneal endometriosis; ovarian endometriosis; deep infiltrating endometriosis; adenomyosis

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MDPI and ACS Style

Ottolina, J.; Villanacci, R.; D’Alessandro, S.; He, X.; Grisafi, G.; Ferrari, S.M.; Candiani, M. Endometriosis and Adenomyosis: Modern Concepts of Their Clinical Outcomes, Treatment, and Management. J. Clin. Med. 2024, 13, 3996. https://doi.org/10.3390/jcm13143996

AMA Style

Ottolina J, Villanacci R, D’Alessandro S, He X, Grisafi G, Ferrari SM, Candiani M. Endometriosis and Adenomyosis: Modern Concepts of Their Clinical Outcomes, Treatment, and Management. Journal of Clinical Medicine. 2024; 13(14):3996. https://doi.org/10.3390/jcm13143996

Chicago/Turabian Style

Ottolina, Jessica, Roberta Villanacci, Sara D’Alessandro, Xuemin He, Giorgia Grisafi, Stefano Maria Ferrari, and Massimo Candiani. 2024. "Endometriosis and Adenomyosis: Modern Concepts of Their Clinical Outcomes, Treatment, and Management" Journal of Clinical Medicine 13, no. 14: 3996. https://doi.org/10.3390/jcm13143996

APA Style

Ottolina, J., Villanacci, R., D’Alessandro, S., He, X., Grisafi, G., Ferrari, S. M., & Candiani, M. (2024). Endometriosis and Adenomyosis: Modern Concepts of Their Clinical Outcomes, Treatment, and Management. Journal of Clinical Medicine, 13(14), 3996. https://doi.org/10.3390/jcm13143996

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