The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome
Abstract
1. Introduction
2. Methods
Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Group | Constipation; Age ≥ 50; [50–96] | Constipation; Age > 50; [16–49] | Control; Age ≥ 50; [50–89] | p Value |
---|---|---|---|---|
n = 4359 | n = 1119 | n = 4100 | ||
Demographics | ||||
Age (years) | 10.2 ± 66.7 | 9.2 ± 39.1 | 6.8 ± 59.4 | p1,2 < 0.001 |
Sex (Male) | 2074 (48%) | 446 (40%) | 2206 (54%) | p1,2 < 0.001 |
Ethnicity (Jewish) | 3754 (86%) | 764 (68%) | 3889 (95%) | p1,2 < 0.001 |
Endoscopy—Setting and Sedation | ||||
Setting (Outpatient) | 3778 (87%) | 1033 (92.3%) | 4019 (98%) | p1,2 < 0.001 |
Sedation provider (AN) | 116 (2.8%) | 35 (3.1%) | 71 (1.7%) | p1,2 < 0.001 |
Sedation provider (NAN) | ||||
Propofol monotherapy | 229 (5.4%) | 73 (6.7%) | 267 (6.6%) | p1,2 > 0.05 |
Propfol + BDZ | 4014 (94.6%) | 1011 (93.3%) | 3762 (93.7%) | p1,2 > 0.05 |
PS-High dose | 307 (7%) | 70 (6%) | 126 (3%) | p1,2 < 0.001 |
Endoscopic Findings | ||||
Bowel preparation | ||||
Moviprep © | 3679 (84.4%) | 964 (86.0%) | 3505 (85.6%) | p1,2 > 0.05 |
Meroken © | 470 (10.1%) | 104 (9.3%) | 361 (8.8%) | |
Other/Unspecified | 210 (4.8%) | 51 (4.6%) | 234 (5.7%) | |
Bowel preparation | 3720 (85.3%) | 978 (87.3%) | 5024 (92.7%) | p1,2 < 0.001 |
(Adequate) | ||||
Cecal intubation | 3640 (84.0%) | 951 (85%) | 3945 (96.1%) | p1,2 < 0.001 |
Terminal ileum intubation | 60 (1.4%) | 29 (2.4%) | 64 (1.6%) | p1,2 > 0.05 |
Melanosis coli | 139 (3.2%) | 27 (2.4%) | 1 (0.0%) | p1,2 < 0.001 |
Polyp detection rate | 890 (20.4%) | 76 (6.8%) | 880 (21.5%) | p1 = 0.65 |
p2 < 0.01 | ||||
Colorectal cancer | 27 (0.6%) | 1 (0.1%) | 12 (0.3%) | p1 = 0.03 |
p2 = 0.15 | ||||
Inflammatory bowel disease | 21 (0.5%) | 19 (1.7%) | 6 (0.1%) | p1,2 < 0.001 |
Parameter | p Value | Odds Ratio | Confidence Interval |
---|---|---|---|
Polyp detection predictors | |||
Patient’s age (years) | <0.001 | 1.034 | 1.03–1.04 |
Sex (male) | <0.001 | 1.514 | 1.36–1.67 |
Ethnicity (Jewish) | 0.07 | 1.171 | 0.98–1.39 |
Constipation | 0.51 | 1.091 | 0.84–1.41 |
Bowel preparation (adequate) | 0.002 | 1.192 | 1.07–1.33 |
Inflammatory bowel disease | 0.046 | 0.226 | 0.05–0.94 |
Colorectal cancer predictors | |||
Patient’s age (years) | <0.01 | 1.044 | 1.02–1.07 |
Sex (male) | 0.81 | 0.936 | 0.54–1.62 |
Ethnicity (Jewish) | 0.92 | 0.958 | 0.40–2.29 |
Constipation | 0.15 | 0.620 | 0.32–1.18 |
Bowel preparation (adequate) | 0.73 | 1.108 | 0.61–1.99 |
Inflammatory bowel disease | 0.08 | 1.161 | 0.96–1.33 |
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Abu Baker, F.; Mari, A.; Taher, R.; Nicola, D.; Gal, O.; Zeina, A.-R. The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome. J. Clin. Med. 2024, 13, 2910. https://doi.org/10.3390/jcm13102910
Abu Baker F, Mari A, Taher R, Nicola D, Gal O, Zeina A-R. The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome. Journal of Clinical Medicine. 2024; 13(10):2910. https://doi.org/10.3390/jcm13102910
Chicago/Turabian StyleAbu Baker, Fadi, Amir Mari, Randa Taher, Dorin Nicola, Oren Gal, and Abdel-Rauf Zeina. 2024. "The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome" Journal of Clinical Medicine 13, no. 10: 2910. https://doi.org/10.3390/jcm13102910
APA StyleAbu Baker, F., Mari, A., Taher, R., Nicola, D., Gal, O., & Zeina, A.-R. (2024). The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome. Journal of Clinical Medicine, 13(10), 2910. https://doi.org/10.3390/jcm13102910