Alveolar Bone Grafting in Unilateral Cleft Lip and Palate: Impact of Timing on Palatal Shape
Abstract
:1. Introduction
2. Material and Methods
2.1. Participants
2.2. Treatment Protocol
2.3. Evaluation Methods
2.4. Statistical Analysis
3. Results
3.1. Demographic Data and Method Error
3.2. Procrustes Superimposition and PCA
3.3. Intergroup Differences
4. Discussion
5. Limitations
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Age at Cleft Repair (Yrs.) Mean (SD), [min–max] | Age at ABG (Yrs.) Mean (SD), [min–max] | Age at Collection of Models (Yrs.) Mean (SD), [min–max] | |
---|---|---|---|
Early ABG | |||
males (n = 21) | 0.6 (0.1); [0.4–0.8] | 2.1 (0.6); [1.4–4.1] | 9.5 (0.8); [8–11.3] |
females (n = 7) | 0.7 (0.2); [0.5–1.1] | 2.1 (0.5); [1.6–3.1] | 9.8 (0.4); [8.8–10.1] |
males and females (n = 28) | 0.6 (0.1); [0.4–1.1] | 2.1 (0.6); [1.4–4.1] | 9.5 (0.7); [8–11.3] |
Late ABG | |||
males (n = 19) | 0.8 (0.2); [0.5–1.2] | 8.5 (1.2); [7.3–12.8] | 11.3 (1.5); [9.5–13.9] |
females (n= 14) | 0.7 (0.1); [0.5–1] | 8.7 (1.4); [7.2–12.9] | 10.1 (1.3); [8–13.9] |
males and females (n = 33) | 0.7 (0.2); [0.5–1.2] | 8.6 (1.3); [7.2–12.9] | 10.8; 1.5; [8–13.9] |
Control | |||
males (n = 25) | N/A | N/A | 8.5 (1); [6.8–11.6] |
females (n = 35) | N/A | N/A | 8.6 (1.4); [6.3–11.8] |
males and females (n = 60) | N/A | N/A | 8.6 (1.2); [6.3–11.8] |
% Variance | % Cumulative Variance | Broken-Stick Criterion | Variance | |
---|---|---|---|---|
PC1 | 26.1% | 26.1% | 1.0% | 0.003247 |
PC2 | 12.0% | 38.1% | 0.9% | 0.001487 |
PC3 | 11.9% | 49.9% | 0.8% | 0.001480 |
PC4 | 7.8% | 57.7% | 0.7% | 0.000967 |
PC5 | 6.4% | 64.1% | 0.7% | 0.000799 |
PC6 | 4.7% | 68.8% | 0.7% | 0.000584 |
PC7 | 3.7% | 72.6% | 0.7% | 0.000465 |
PC8 | 3.6% | 76.1% | 0.6% | 0.000444 |
PC9 | 2.9% | 79.1% | 0.6% | 0.000365 |
PC10 | 2.4% | 81.4% | 0.6% | 0.000296 |
PC11 | 2.0% | 83.4% | 0.6% | 0.000244 |
PC12 | 1.6% | 85.0% | 0.6% | 0.000194 |
PC13 | 1.3% | 86.2% | 0.6% | 0.000157 |
PC14 | 1.1% | 87.3% | 0.6% | 0.000137 |
PC15 | 1.0% | 88.3% | 0.5% | 0.000119 |
PC16 | 0.9% | 89.2% | 0.5% | 0.000110 |
PC17 | 0.8% | 90.0% | 0.5% | 0.000098 |
PC18 | 0.7% | 90.7% | 0.5% | 0.000093 |
PC19 | 0.7% | 91.4% | 0.5% | 0.000083 |
PC20 | 0.6% | 91.9% | 0.5% | 0.000070 |
PC21 | 0.5% | 92.4% | 0.5% | 0.000062 |
PC22 | 0.5% | 92.9% | 0.5% | 0.000057 |
Difference in Procrustes Distance | p-Value | |
---|---|---|
Control vs. Early ABG | 0.0951 | <0.001 |
Control vs. Late ABG | 0.0967 | <0.001 |
Early vs. Late ABG | 0.0407 | 0.042 |
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Brudnicki, A.; Petrova, T.; Dubovska, I.; Kuijpers-Jagtman, A.M.; Ren, Y.; Fudalej, P.S. Alveolar Bone Grafting in Unilateral Cleft Lip and Palate: Impact of Timing on Palatal Shape. J. Clin. Med. 2023, 12, 7519. https://doi.org/10.3390/jcm12247519
Brudnicki A, Petrova T, Dubovska I, Kuijpers-Jagtman AM, Ren Y, Fudalej PS. Alveolar Bone Grafting in Unilateral Cleft Lip and Palate: Impact of Timing on Palatal Shape. Journal of Clinical Medicine. 2023; 12(24):7519. https://doi.org/10.3390/jcm12247519
Chicago/Turabian StyleBrudnicki, Andrzej, Tereza Petrova, Ivana Dubovska, Anne Marie Kuijpers-Jagtman, Yijin Ren, and Piotr S. Fudalej. 2023. "Alveolar Bone Grafting in Unilateral Cleft Lip and Palate: Impact of Timing on Palatal Shape" Journal of Clinical Medicine 12, no. 24: 7519. https://doi.org/10.3390/jcm12247519