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Article

Assessing the Impact of an Advanced Clinical Decision Support System on Medication Safety and Hospital Readmissions in an Innovative Transitional Care Model: A Pilot Study

1
Tabula Rasa HealthCare, Office of Translational Research & Residency Programs, 228 Strawbridge Dr, Moorestown, NJ 08057, USA
2
College of Pharmacy, University of Arizona, Tucson, AZ 85721, USA
3
Tabula Rasa HealthCare, Precision Pharmacotherapy Research & Development Institute, 13485 Veterans Way, Orlando, FL 32827, USA
4
Faculty of Pharmacy, Universite de Montreal, Pavillon Jean-Coutu, 2940, Chemin de la Polytechnique, Montreal, QC H3T IJ4, Canada
*
Author to whom correspondence should be addressed.
Academic Editor: Alex Sparreboom
J. Clin. Med. 2022, 11(8), 2070; https://doi.org/10.3390/jcm11082070
Received: 25 February 2022 / Revised: 22 March 2022 / Accepted: 5 April 2022 / Published: 7 April 2022
(This article belongs to the Section Pharmacology)
(1) Background: Adverse drug events and inappropriate use of medications lead to hospitalizations, medication-related morbidity, and mortality. This study examined whether a novel medication risk prediction tool, the MedWise Risk Score™, was associated with medication safety-related problem (MRP) identification and whether integration into an existing innovative transitions of care (TOC) service could decrease readmissions. (2) Methods: This retrospective comparator group study assessed patients discharged from a hospital in southern Arizona between January and December 2020. Participants were included in the study if they were 18 years of age or older, referred to the pharmacist for TOC services, and received a pharmacist consultation within one-week post discharge. Patients were categorized into two groups: (1) medication safety review (MSR)-TOC service (intervention) or (2) existing innovative TOC service (control). (3) Results: Of 164 participants, most were male (57%) and were between 70–79 years of age. Overall, there were significantly more drug-drug interactions (DDI) MRPs identified per patient in the intervention vs. control group for those who were readmitted (3.7 ± 1.5 vs. 0.9 ± 0.6, p < 0.001) and those who were not readmitted (2 ± 1.3 vs. 1.3 ± 1.2, p = 0.0120). Furthermore, of those who were readmitted, the average number of identified MRPs per patient was greater in the intervention group compared to the control (6.3 vs. 2.5, respectively, p > 0.05). Relative to the control, the readmission frequency was 30% lower in the treatment group; however, there was insufficient power to detect significant differences between groups. (4) Conclusions: The integration of a medication risk prediction tool into this existing TOC service identified more DDI MRPs compared to the previous innovative TOC service, which lends evidence that supports its ability to prevent readmissions. Future work is warranted to demonstrate the longitudinal impact of this intervention in a larger sample size. View Full-Text
Keywords: transition of care; clinical decision support system; pharmacist transition of care; clinical decision support system; pharmacist
MDPI and ACS Style

Bingham, J.M.; Baugham, L.; Hilaneh, A.; Tranchina, K.; Arku, D.; Eckert, B.; Scovis, N.; Turgeon, J. Assessing the Impact of an Advanced Clinical Decision Support System on Medication Safety and Hospital Readmissions in an Innovative Transitional Care Model: A Pilot Study. J. Clin. Med. 2022, 11, 2070. https://doi.org/10.3390/jcm11082070

AMA Style

Bingham JM, Baugham L, Hilaneh A, Tranchina K, Arku D, Eckert B, Scovis N, Turgeon J. Assessing the Impact of an Advanced Clinical Decision Support System on Medication Safety and Hospital Readmissions in an Innovative Transitional Care Model: A Pilot Study. Journal of Clinical Medicine. 2022; 11(8):2070. https://doi.org/10.3390/jcm11082070

Chicago/Turabian Style

Bingham, Jennifer M., Lindsey Baugham, Andriana Hilaneh, Karley Tranchina, Daniel Arku, Becka Eckert, Nicole Scovis, and Jacques Turgeon. 2022. "Assessing the Impact of an Advanced Clinical Decision Support System on Medication Safety and Hospital Readmissions in an Innovative Transitional Care Model: A Pilot Study" Journal of Clinical Medicine 11, no. 8: 2070. https://doi.org/10.3390/jcm11082070

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