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Volume 11
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10.3390/jcm11030669
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Article

Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia

by
Ivan Blokhin
1,*,
Victor Gombolevskiy
2,
Valeria Chernina
1,
Maxim Gusev
3,
Pavel Gelezhe
1,
Olga Aleshina
4,
Alexander Nikolaev
1,
Nicholas Kulberg
5,
Sergey Morozov
1 and
Roman Reshetnikov
1,6
1
Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, 127051 Moscow, Russia
2
Artificial Intelligence Research Institute (AIRI), 105064 Moscow, Russia
3
Moscow Polytechnic University, 107023 Moscow, Russia
4
City Clinical Hospital No. 13 of the Moscow Health Care Department, 115280 Moscow, Russia
5
Federal Research Center “Computer Science and Control” of Russian Academy of Sciences, 119333 Moscow, Russia
6
Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia
*
Author to whom correspondence should be addressed.
Academic Editors: Francesco Bianco and Nazario Carrabba
J. Clin. Med. 2022, 11(3), 669; https://doi.org/10.3390/jcm11030669
Received: 11 December 2021 / Revised: 21 January 2022 / Accepted: 24 January 2022 / Published: 27 January 2022
(This article belongs to the Special Issue Thoracic and Cardiac Imaging in Patients with the Coronavirus Disease 2019 (COVID-19))
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Abstract

Computed tomography (CT) has been an essential diagnostic tool during the COVID-19 pandemic. The study aimed to develop an optimal CT protocol in terms of safety and reliability. For this, we assessed the inter-observer agreement between CT and low-dose CT (LDCT) with soft and sharp kernels using a semi-quantitative severity scale in a prospective study (Moscow, Russia). Two consecutive scans with CT and LDCT were performed in a single visit. Reading was performed by ten radiologists with 3–25 years’ experience. The study included 230 patients, and statistical analysis showed LDCT with a sharp kernel as the most reliable protocol (percentage agreement 74.35 ± 43.77%), but its advantage was marginal. There was no significant correlation between radiologists’ experience and average percentage agreement for all four evaluated protocols. Regarding the radiation exposure, CTDIvol was 3.6 ± 0.64 times lower for LDCT. In conclusion, CT and LDCT with soft and sharp reconstructions are equally reliable for COVID-19 reporting using the “CT 0-4” scale. The LDCT protocol allows for a significant decrease in radiation exposure but may be restricted by body mass index. View Full-Text
Keywords: COVID-19; SARS-CoV-2; pneumonia; tomography; X-ray computed COVID-19; SARS-CoV-2; pneumonia; tomography; X-ray computed
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MDPI and ACS Style

Blokhin, I.; Gombolevskiy, V.; Chernina, V.; Gusev, M.; Gelezhe, P.; Aleshina, O.; Nikolaev, A.; Kulberg, N.; Morozov, S.; Reshetnikov, R. Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia. J. Clin. Med. 2022, 11, 669. https://doi.org/10.3390/jcm11030669

AMA Style

Blokhin I, Gombolevskiy V, Chernina V, Gusev M, Gelezhe P, Aleshina O, Nikolaev A, Kulberg N, Morozov S, Reshetnikov R. Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia. Journal of Clinical Medicine. 2022; 11(3):669. https://doi.org/10.3390/jcm11030669

Chicago/Turabian Style

Blokhin, Ivan, Victor Gombolevskiy, Valeria Chernina, Maxim Gusev, Pavel Gelezhe, Olga Aleshina, Alexander Nikolaev, Nicholas Kulberg, Sergey Morozov, and Roman Reshetnikov. 2022. "Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia" Journal of Clinical Medicine 11, no. 3: 669. https://doi.org/10.3390/jcm11030669

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