Galectin-1 and Galectin-9 Concentration in Maternal Serum: Implications in Pregnancies Complicated with Preterm Prelabor Rupture of Membranes
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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pPROM (n = 37) | Control (n = 38) | p Value | |
---|---|---|---|
Age (years) | 31.62 ± 5.12 | 28.95 ± 6.26 | 0.05 |
Gravida * | 2 | 2 | 0.11 |
BMI at blood sampling (kg/m2) | 26.13 ± 4.04 | 26.56 ± 4.626 | 0.67 |
GA at blood sampling | 32.30 ± 3.08 | 30.29 ± 3.27 | 0.008 |
GA at delivery | 34.43 ± 2.72 | 38.47 ± 1.14 | <0.00001 |
C-section (%) ** | 35.14 | 26.67 | 0.46 |
Female neonate (%) ** | 35.14 | 50 | 0.22 |
Birth weight (g) | 2407.97 ± 575.35 | 3456.50 ± 383.94 | <0.000001 |
pH of the neonate at birth | 7.27 ± 0.08 | 7.27 ± 0.06 | 0.65 |
WBC count | 12.59 ± 3.11 | 10.81 ± 2.35 | 0.08 |
CRP | 5.76 ± 6.80 | 5.91± 2.97 | 0.80 |
Galectin-1 (ng/mL) * | 13.32 (6.29) | 14.71 (10.34) | 0.02 |
Galectin-9 (ng/mL) | 13.307 ± 4.09 | 14.76 ± 7.47 | 0.30 |
pPROM < 32 (n = 13) | pPROM > 32 (n = 24) | Control (n = 38) | p Value | |
---|---|---|---|---|
Age (years) | 31.69 ± 3.33 | 31.58 ± 5.94 | 28.95 ± 6.26 | 0.14 |
Gravida * | 2 | 2 | 2 | 0.11 |
BMI at blood sampling (kg/m2) | 25.73 ± 4.29 | 26.34 ± 3.98 | 26.56 ± 4.63 | 0.84 |
GA at blood sampling | 28.85 ± 2.44 | 34.17 ± 1.17 | 30.29 ± 3.27 | <0.000001 |
GA at delivery | 33.08 ± 3.68 | 35.17 ± 1.71 | 38.47 ± 1.14 | <0.000001 |
C-section (%) ** | 38.46 | 31.53 | 26.67 | 0.15 |
Female neonate (%) ** | 30.77 | 38.12 | 50 | 0.45 |
Birth weight (g) | 2185.38 ± 754.98 | 2528.54 ± 421.39 | 3456.50 ± 383.94 | <0.000001 |
pH of the neonate at birth | 7.26 ± 0.07 | 7.8 ± 0.06 | 7.27 ± 0.06 | 0.84 |
WBC count | 13.34 ± 3.24 | 12.18 ± 3.03 | 10.81 ± 2.35 | 0.11 |
CRP | 7.19 ± 6.87 | 4.98 ± 6.78 | 5.19 ± 2.97 | 0.57 |
Galectin-1 (ng/mL) * | 8.85 (3.54) | 14.45 (5.14) | 14.71 (10.34) | 0.0004 |
Galectin-9 (ng/mL) | 11.57 ± 3.42 | 14.25 ± 4.18 | 14.76 ± 7.47 | 0.26 |
Galectin-1 | Galectin-9 | |
---|---|---|
Age | R = 0.18 | R = −0.03 |
p = 0.12 | p = 0.80 | |
BMI | R = 0.11 | R = 0.34 |
p = 0.33 | p = 0.003 | |
GA at blood sampling | R = 0.15 | R = 0.08 |
p = 0.19 | p = 0.52 | |
GA at delivery | R = 0.33 | R = 0.17 |
p = 0.007 | p = 0.15 | |
Birth weight | R = 0.32 | R = 0.09 |
p = 0.008 | p = 0.49 | |
pH of the neonate at birth | R = −0.11 | R = 0.14 |
p = 0.38 | p = 0.25 | |
WBC | R = −0.25 | R = 0.04 |
p = 0.09 | p = 0.79 | |
CRP | R = 0.33 | R = 0.04 |
p = 0.82 | p = 0.79 |
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Boroń, D.G.; Świetlicki, A.; Potograbski, M.; Kurzawińska, G.; Wirstlein, P.; Boroń, D.; Drews, K.; Seremak-Mrozikiewicz, A. Galectin-1 and Galectin-9 Concentration in Maternal Serum: Implications in Pregnancies Complicated with Preterm Prelabor Rupture of Membranes. J. Clin. Med. 2022, 11, 6330. https://doi.org/10.3390/jcm11216330
Boroń DG, Świetlicki A, Potograbski M, Kurzawińska G, Wirstlein P, Boroń D, Drews K, Seremak-Mrozikiewicz A. Galectin-1 and Galectin-9 Concentration in Maternal Serum: Implications in Pregnancies Complicated with Preterm Prelabor Rupture of Membranes. Journal of Clinical Medicine. 2022; 11(21):6330. https://doi.org/10.3390/jcm11216330
Chicago/Turabian StyleBoroń, Dorota Grażyna, Aleksy Świetlicki, Michał Potograbski, Grażyna Kurzawińska, Przemysław Wirstlein, Daniel Boroń, Krzysztof Drews, and Agnieszka Seremak-Mrozikiewicz. 2022. "Galectin-1 and Galectin-9 Concentration in Maternal Serum: Implications in Pregnancies Complicated with Preterm Prelabor Rupture of Membranes" Journal of Clinical Medicine 11, no. 21: 6330. https://doi.org/10.3390/jcm11216330