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Perspective

Urinary Biomarkers for Early Diagnosis of Lung Cancer

1
Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Via Giuseppe Ripamonti 435, 20141 Milan, Italy
2
Division of Epidemiology and Biostatistics, IEO, European Institute of Oncology IRCCS, Via Giuseppe Ripamonti 435, 20141 Milan, Italy
3
Department of Oncology and Hemato-Oncology, University of Milan, Via Festa del Perdono 7, 20122 Milan, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Takashi Ohtsuka and Emmanuel Andrès
J. Clin. Med. 2021, 10(8), 1723; https://doi.org/10.3390/jcm10081723
Received: 10 March 2021 / Revised: 29 March 2021 / Accepted: 11 April 2021 / Published: 16 April 2021
(This article belongs to the Section Oncology)
Lung cancer is the leading cause of cancer deaths worldwide. Its early detection has the potential to significantly impact the burden of the disease. The screening and diagnostic techniques in current use suffer from limited specificity. The need therefore arises for a reliable biomarker to identify the disease earlier, which can be integrated into a test. This test would also allow for the recurrence risk after surgery to be stratified. In this context, urine could represent a non-invasive alternative matrix, with the urinary metabolomic profile offering a potential source for the discovery of diagnostic biomarkers. This paper aims to examine the current state of research and the potential for translation into clinical practice. View Full-Text
Keywords: lung cancer; urine; biomarker; early diagnosis lung cancer; urine; biomarker; early diagnosis
MDPI and ACS Style

Gasparri, R.; Sedda, G.; Caminiti, V.; Maisonneuve, P.; Prisciandaro, E.; Spaggiari, L. Urinary Biomarkers for Early Diagnosis of Lung Cancer. J. Clin. Med. 2021, 10, 1723. https://doi.org/10.3390/jcm10081723

AMA Style

Gasparri R, Sedda G, Caminiti V, Maisonneuve P, Prisciandaro E, Spaggiari L. Urinary Biomarkers for Early Diagnosis of Lung Cancer. Journal of Clinical Medicine. 2021; 10(8):1723. https://doi.org/10.3390/jcm10081723

Chicago/Turabian Style

Gasparri, Roberto, Giulia Sedda, Valentina Caminiti, Patrick Maisonneuve, Elena Prisciandaro, and Lorenzo Spaggiari. 2021. "Urinary Biomarkers for Early Diagnosis of Lung Cancer" Journal of Clinical Medicine 10, no. 8: 1723. https://doi.org/10.3390/jcm10081723

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