Next Article in Journal
Clinical Challenges in the Management of Neuroendocrine Tumors
Next Article in Special Issue
The Investigative Role of Statins in Ameliorating Lower Urinary Tract Symptoms (LUTS): A Systematic Review
Previous Article in Journal
A Deep Learning Method for Alerting Emergency Physicians about the Presence of Subphrenic Free Air on Chest Radiographs
Previous Article in Special Issue
Identifying Markers of Cardiovascular Event-Free Survival in Familial Hypercholesterolemia
Open AccessArticle

Evaluation of Transthoracic Echocardiography in the Assessment of Atherosclerosis of the Left Main Coronary Artery: Comparison with Optical Frequency Domain Imaging (a Pilot Study)

1
Department of Cardiology, Centre Hospitalier Universitaire de Caen, 14000 Caen, France
2
Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy
3
Faculty of Health and Medical Sciences, School of Medicine, University of Western Australia, Perth, WA 6009, Australia
4
Lipid Disorders Clinic, Cardiometabolic Services, Department of Cardiology, Royal Perth Hospital, Perth, WA 6000, Australia
5
Centro Dislipidemie, ASST Grande Ospedale Metropolitano Niguarda Ca’ Granda, 20162 Milano, Italy
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2021, 10(2), 256; https://doi.org/10.3390/jcm10020256
Received: 28 November 2020 / Revised: 6 January 2021 / Accepted: 7 January 2021 / Published: 12 January 2021
Background: Risk stratification using non-invasive imaging of the coronary vessels is emerging as an optimal standard of care for patients with dyslipidemias. Of particular interest is the evaluation of the left main coronary artery (LMCA), where calcium deposition appears to be a predictor of cardiovascular events. Methods: In coronary patients, we evaluated wall thickness and internal diameter of the LMCA examined by transthoracic echocardiography (TTE) and compared these with findings obtained by optical frequency domain imaging (OFDI), this latter also used to evaluate calcium deposition. Results: A significant positive correlation between TTE and OFDI for the anterior wall thickness (r = 0.41, p = 0.043) and internal diameter (r = 0.36, p = 0.048) of the LMCA was detected. Echocardiographic wall measurements were higher in patients with fibro-calcific plaques. The receiver operating characteristic (ROC) curve showed that an anterior wall thickness of LMCA ≥ 1.4 mm was predictive of fibro-calcific plaque (area under the curve = 0.815 and p = 0.006), sensitivity and specificity being 76.9% and 80%, respectively (Youden’s Index = 0.56). Conclusions: Measurement of anterior wall thickness of the LMCA by TTE and OFDI appears to be closely correlated and may predict the presence of coronary calcification. View Full-Text
Keywords: atherosclerosis; echocardiography; left main coronary; optical frequency domain imaging atherosclerosis; echocardiography; left main coronary; optical frequency domain imaging
Show Figures

Figure 1

MDPI and ACS Style

Labombarda, F.; Roule, V.; Rebouh, I.; Ruscica, M.; Watts, G.F.; Sirtori, C.R. Evaluation of Transthoracic Echocardiography in the Assessment of Atherosclerosis of the Left Main Coronary Artery: Comparison with Optical Frequency Domain Imaging (a Pilot Study). J. Clin. Med. 2021, 10, 256. https://doi.org/10.3390/jcm10020256

AMA Style

Labombarda F, Roule V, Rebouh I, Ruscica M, Watts GF, Sirtori CR. Evaluation of Transthoracic Echocardiography in the Assessment of Atherosclerosis of the Left Main Coronary Artery: Comparison with Optical Frequency Domain Imaging (a Pilot Study). Journal of Clinical Medicine. 2021; 10(2):256. https://doi.org/10.3390/jcm10020256

Chicago/Turabian Style

Labombarda, Fabien; Roule, Vincent; Rebouh, Idir; Ruscica, Massimiliano; Watts, Gerald F.; Sirtori, Cesare R. 2021. "Evaluation of Transthoracic Echocardiography in the Assessment of Atherosclerosis of the Left Main Coronary Artery: Comparison with Optical Frequency Domain Imaging (a Pilot Study)" J. Clin. Med. 10, no. 2: 256. https://doi.org/10.3390/jcm10020256

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop