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Article

Assessing Acceptability of COVID-19 Vaccine Booster Dose among Adult Americans: A Cross-Sectional Study

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Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89102, USA
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Office of Research, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89102, USA
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Department of Medical Education and Office of Academic Affairs, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89102, USA
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Author to whom correspondence should be addressed.
Academic Editor: Ralph A. Tripp
Vaccines 2021, 9(12), 1424; https://doi.org/10.3390/vaccines9121424
Received: 26 October 2021 / Revised: 22 November 2021 / Accepted: 30 November 2021 / Published: 2 December 2021
Given the emergence of breakthrough infections, new variants, and concerns of waning immunity from the primary COVID-19 vaccines, booster shots emerged as a viable option to shore-up protection against COVID-19. Following the recent authorization of vaccine boosters among vulnerable Americans, this study aims to assess COVID-19 vaccine booster hesitancy and its associated factors in a nationally representative sample. A web-based 48-item psychometric valid survey was used to measure vaccine literacy, vaccine confidence, trust, and general attitudes towards vaccines. Data were analyzed through Chi-square (with a post hoc contingency table analysis) and independent-sample t-/Welch tests. Among 2138 participants, nearly 62% intended to take booster doses and the remaining were COVID-19 vaccine booster hesitant. The vaccine-booster-hesitant group was more likely to be unvaccinated (62.6% vs. 12.9%) and did not intend to have their children vaccinated (86.1% vs. 27.5%) compared to their non-hesitant counterparts. A significantly higher proportion of booster dose hesitant individuals had very little to no trust in the COVID-19 vaccine information given by public health/government agencies (55% vs. 12%) compared to non-hesitant ones. The mean scores of vaccine confidence index and vaccine literacy were lower among the hesitant group compared to the non-hesitant group. Compared to the non-hesitant group, vaccine hesitant participants were single or never married (41.8% vs. 28.7%), less educated, and living in a southern region of the nation (40.9% vs. 33.3%). These findings underscore the need of developing effective communication strategies emphasizing vaccine science in ways that are accessible to individuals with lower levels of education and vaccine literacy to increase vaccination uptake. View Full-Text
Keywords: COVID-19; vaccine hesitancy; vaccine literacy; functional literacy; communicative literacy; critical literacy; vaccine confidence index; herd immunity; vaccine booster COVID-19; vaccine hesitancy; vaccine literacy; functional literacy; communicative literacy; critical literacy; vaccine confidence index; herd immunity; vaccine booster
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MDPI and ACS Style

Yadete, T.; Batra, K.; Netski, D.M.; Antonio, S.; Patros, M.J.; Bester, J.C. Assessing Acceptability of COVID-19 Vaccine Booster Dose among Adult Americans: A Cross-Sectional Study. Vaccines 2021, 9, 1424. https://doi.org/10.3390/vaccines9121424

AMA Style

Yadete T, Batra K, Netski DM, Antonio S, Patros MJ, Bester JC. Assessing Acceptability of COVID-19 Vaccine Booster Dose among Adult Americans: A Cross-Sectional Study. Vaccines. 2021; 9(12):1424. https://doi.org/10.3390/vaccines9121424

Chicago/Turabian Style

Yadete, Tesfaye, Kavita Batra, Dale M. Netski, Sabrina Antonio, Michael J. Patros, and Johan C. Bester. 2021. "Assessing Acceptability of COVID-19 Vaccine Booster Dose among Adult Americans: A Cross-Sectional Study" Vaccines 9, no. 12: 1424. https://doi.org/10.3390/vaccines9121424

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