A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies
1
Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD 4811, Australia
2
College of Medicine and Dentistry, James Cook University, Townsville, QLD 4811, Australia
3
College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia
*
Author to whom correspondence should be addressed.
Vaccines 2021, 9(1), 32; https://doi.org/10.3390/vaccines9010032
Received: 25 November 2020
/
Revised: 28 December 2020
/
Accepted: 5 January 2021
/
Published: 8 January 2021
(This article belongs to the Special Issue Mosquito-Borne Viruses: Fundamental Biology and Therapeutic Intervention)
Arthropod-borne viruses (Arboviruses) continue to generate significant health and economic burdens for people living in endemic regions. Of these viruses, some of the most important (e.g., dengue, Zika, chikungunya, and yellow fever virus), are transmitted mainly by Aedes mosquitoes. Over the years, viral infection control has targeted vector population reduction and inhibition of arboviral replication and transmission. This control includes the vector control methods which are classified into chemical, environmental, and biological methods. Some of these control methods may be largely experimental (both field and laboratory investigations) or widely practised. Perceptively, one of the biological methods of vector control, in particular, Wolbachia-based control, shows a promising control strategy for eradicating Aedes-borne arboviruses. This can either be through the artificial introduction of Wolbachia, a naturally present bacterium that impedes viral growth in mosquitoes into heterologous Aedes aegypti mosquito vectors (vectors that are not natural hosts of Wolbachia) thereby limiting arboviral transmission or via Aedes albopictus mosquitoes, which naturally harbour Wolbachia infection. These strategies are potentially undermined by the tendency of mosquitoes to lose Wolbachia infection in unfavourable weather conditions (e.g., high temperature) and the inhibitory competitive dynamics among co-circulating Wolbachia strains. The main objective of this review was to critically appraise published articles on vector control strategies and specifically highlight the use of Wolbachia-based control to suppress vector population growth or disrupt viral transmission. We retrieved studies on the control strategies for arboviral transmissions via arthropod vectors and discussed the use of Wolbachia control strategies for eradicating arboviral diseases to identify literature gaps that will be instrumental in developing models to estimate the impact of these control strategies and, in essence, the use of different Wolbachia strains and features.
View Full-Text
Keywords:
Aedes-borne; arboviruses; Wolbachia; vectors; controls
▼
Show Figures
Figure 1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Ogunlade, S.T.; Meehan, M.T.; Adekunle, A.I.; Rojas, D.P.; Adegboye, O.A.; McBryde, E.S. A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies. Vaccines 2021, 9, 32. https://doi.org/10.3390/vaccines9010032
AMA Style
Ogunlade ST, Meehan MT, Adekunle AI, Rojas DP, Adegboye OA, McBryde ES. A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies. Vaccines. 2021; 9(1):32. https://doi.org/10.3390/vaccines9010032
Chicago/Turabian StyleOgunlade, Samson T., Michael T. Meehan, Adeshina I. Adekunle, Diana P. Rojas, Oyelola A. Adegboye, and Emma S. McBryde. 2021. "A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies" Vaccines 9, no. 1: 32. https://doi.org/10.3390/vaccines9010032
Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
