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Vaccines
Volume 11
Issue 7
10.3390/vaccines11071138
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Perspective

Critical Elements of an Mpox Vaccination Model at the Largest Public Health Hospital System in the United States

by
Anthony J. Lo Piccolo
1,2,*,
Justin Chan
2,3,
Gabriel M. Cohen
2,3,
Ofole Mgbako
2,3,4,
Robert A. Pitts
2,3,
Radu Postelnicu
2,3,
Andrew Wallach
2,3 and
Vikramjit Mukherjee
2,3
1
Division of Infectious Diseases & Immunology, NYU Langone Health, New York, NY 10016, USA
2
NYC Health + Hospitals (NYC H+H)/Bellevue, New York, NY 10016, USA
3
Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA
4
Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA
*
Author to whom correspondence should be addressed.
Vaccines 2023, 11(7), 1138; https://doi.org/10.3390/vaccines11071138
Submission received: 30 April 2023 / Revised: 9 June 2023 / Accepted: 16 June 2023 / Published: 23 June 2023
(This article belongs to the Special Issue Vaccines Uptakes and Public Health)
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Abstract

In the spring of 2022, mpox spread to non-endemic countries, including the United States. In New York City (NYC), vaccine demand grew as quickly as case counts. With the leadership of the Regional Emerging Special Pathogens Treatment Center (RESPTC) at NYC Health and Hospitals/Bellevue (NYC H+H)—part of the largest public hospital system in the United States—an innovative vaccination model was established that overcame challenges involving health inequities, inadequate access, and lack of vaccine uptake, to successfully administer JYNNEOS vaccines to over 12,000 patients. Transmission has slowed since its peak in August 2022, which has been attributed to successful vaccination campaigns, infection-induced immunity, and behavioral changes among those at highest risk; however, a Centers for Disease Control and Prevention (CDC) assessment released on 4 April 2023 suggests jurisdictions with low vaccination levels (<35%) remain at risk for an mpox resurgence. Here, we summarize the critical aspects of our mpox vaccination model in NYC, which include integration into routine clinical care, prioritization of health equity, and reutilization of COVID-19 vaccination systems, to provide valuable insights for healthcare institutions as we move into the next stage of this ongoing outbreak.
Keywords: mpox; mpox vaccine; JYNNEOS; vaccine equity; vaccine uptake; community outreach; vaccine rollout; public health emergency; emergency preparedness; special pathogen preparedness mpox; mpox vaccine; JYNNEOS; vaccine equity; vaccine uptake; community outreach; vaccine rollout; public health emergency; emergency preparedness; special pathogen preparedness

Share and Cite

MDPI and ACS Style

Piccolo, A.J.L.; Chan, J.; Cohen, G.M.; Mgbako, O.; Pitts, R.A.; Postelnicu, R.; Wallach, A.; Mukherjee, V. Critical Elements of an Mpox Vaccination Model at the Largest Public Health Hospital System in the United States. Vaccines 2023, 11, 1138. https://doi.org/10.3390/vaccines11071138

AMA Style

Piccolo AJL, Chan J, Cohen GM, Mgbako O, Pitts RA, Postelnicu R, Wallach A, Mukherjee V. Critical Elements of an Mpox Vaccination Model at the Largest Public Health Hospital System in the United States. Vaccines. 2023; 11(7):1138. https://doi.org/10.3390/vaccines11071138

Chicago/Turabian Style

Piccolo, Anthony J. Lo, Justin Chan, Gabriel M. Cohen, Ofole Mgbako, Robert A. Pitts, Radu Postelnicu, Andrew Wallach, and Vikramjit Mukherjee. 2023. "Critical Elements of an Mpox Vaccination Model at the Largest Public Health Hospital System in the United States" Vaccines 11, no. 7: 1138. https://doi.org/10.3390/vaccines11071138

APA Style

Piccolo, A. J. L., Chan, J., Cohen, G. M., Mgbako, O., Pitts, R. A., Postelnicu, R., Wallach, A., & Mukherjee, V. (2023). Critical Elements of an Mpox Vaccination Model at the Largest Public Health Hospital System in the United States. Vaccines, 11(7), 1138. https://doi.org/10.3390/vaccines11071138

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