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Insights on the Effects of Resveratrol and Some of Its Derivatives in Cancer and Autoimmunity: A Molecule with a Dual Activity

1
VisMederi srl, Strada del Petriccio e Belriguardo, 35, 53100 Siena, Italy
2
Infectivology and Clinical Trials Research Department, Children’s Hospital Bambino Gesù, Viale San Paolo 15, 00146 Rome, Italy
*
Author to whom correspondence should be addressed.
Antioxidants 2020, 9(2), 91; https://doi.org/10.3390/antiox9020091
Received: 8 January 2020 / Revised: 17 January 2020 / Accepted: 20 January 2020 / Published: 22 January 2020
In recent years, the interest in natural compounds exerting immunoregulatory effects has enormously increased. Among these, the polyphenol resveratrol, found in a variety of foods and beverages, including red grapes and red wine, has been demonstrated to exert both in vitro and in vivo biological activities. More specifically, it has antiaging, cardioprotective, antioxidant, immunomodulatory, anti-inflammatory and chemopreventive activities. Due to its anti-proliferative, pro-apoptotic and immunoregulatory effects, resveratrol has gained substantial attention for the treatment of cancer or autoimmunity, which represent frequently diagnosed diseases with important consequences for the health of the patients affected. The aim of the present review is to focus on the role of resveratrol in the modulation of cancer as well as of several organ-specific or systemic autoimmune diseases, including autoimmune hepatitis, type 1 diabetes mellitus, inflammatory bowel disease, rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis. View Full-Text
Keywords: resveratrol; cancer; autoimmunity resveratrol; cancer; autoimmunity
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MDPI and ACS Style

Gianchecchi, E.; Fierabracci, A. Insights on the Effects of Resveratrol and Some of Its Derivatives in Cancer and Autoimmunity: A Molecule with a Dual Activity. Antioxidants 2020, 9, 91. https://doi.org/10.3390/antiox9020091

AMA Style

Gianchecchi E, Fierabracci A. Insights on the Effects of Resveratrol and Some of Its Derivatives in Cancer and Autoimmunity: A Molecule with a Dual Activity. Antioxidants. 2020; 9(2):91. https://doi.org/10.3390/antiox9020091

Chicago/Turabian Style

Gianchecchi, Elena; Fierabracci, Alessandra. 2020. "Insights on the Effects of Resveratrol and Some of Its Derivatives in Cancer and Autoimmunity: A Molecule with a Dual Activity" Antioxidants 9, no. 2: 91. https://doi.org/10.3390/antiox9020091

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