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Open AccessArticle

In Vitro Antioxidant, Anti-Biofilm, and Solar Protection Activities of Melocactus zehntneri (Britton & Rose) Pulp Extract

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Pós-Graduação em Bioquímica, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Natal, CEP 59078-970, Brazil
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Laboratório de Transformação de Planta e Análise em Microscopia (LTPAM), Departamento de Biologia Celular e Genética, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Natal, CEP 59078-970, Brazil
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Laboratório de Biotecnologia de Polímeros Naturais (BIOPOL), Departamento de Bioquímica, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Natal, CEP 59078-970, Brazil
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Laboratório de Produtos Naturais e Bioativos (PNBio), Departamento de Farmácia, UFRN, Natal, CEP 59078-970, Brazil
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Laboratório de Ensaios Antimicrobianos e de Citotoxicidades (LEAC), Departamento Microbiologia e Parasitologia, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Natal, CEP 59078-970, Brazil
*
Author to whom correspondence should be addressed.
Antioxidants 2019, 8(10), 439; https://doi.org/10.3390/antiox8100439
Received: 18 June 2019 / Revised: 19 August 2019 / Accepted: 20 August 2019 / Published: 1 October 2019
Cactaceae plants are important due to their nutritional and therapeutic values. This study aimed to identify the phytochemical profile and biological activities of six Melocactus zehntneri pulp extracts: hexane extract (HE), chloroform extract (CE), ethanol extract (EE), methanol extract (ME), final water extract (FWE), and water extract (WE). Sugar, phenolic compounds, and protein content of the extracts were determined. Then thin layer chromatography (TLC) was performed to detect the presence of terpenes (ursolic and oleanolic acids), saponins, sugars, and glycoproteins. These extracts were analyzed for antioxidant activity via in vitro assay. HE showed 75% ferric chelating activity. All extracts showed 80–100% superoxide and hydroxyl radical-scavenging activities, respectively. Further, all extracts at 25 µg/mL showed 60% activity against DPPH. Moreover, in the 3T3 cells lines, no cytotoxicity was observed; however, therapeutic activity against the effects of the H2O2 treatment was exhibited. Finally, the polar extracts (EE, ME, FWE, and WE), particularly WE, elicited activity against the biofilms of Staphylococcus epidermidis, and HE and CE expressed a capacity for solar protection. View Full-Text
Keywords: coroa-de-frade; antioxidant activity; MTT reduction; SPF coroa-de-frade; antioxidant activity; MTT reduction; SPF
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Aquino-Martins, V.G.Q.; Melo, L.F.M.; Silva, L.M.P.; Targino de Lima, T.R.; Fernandes Queiroz, M.; Viana, R.L.S.; Zucolotto, S.M.; Andrade, V.S.; Rocha, H.A.O.; Scortecci, K.C. In Vitro Antioxidant, Anti-Biofilm, and Solar Protection Activities of Melocactus zehntneri (Britton & Rose) Pulp Extract. Antioxidants 2019, 8, 439.

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