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Disseminated Coccidioidomycosis to the Spine—Case Series and Review of Literature

Loma Linda University Medical Center, Loma Linda, CA 92354, USA
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Brain Sci. 2019, 9(7), 160; https://doi.org/10.3390/brainsci9070160
Received: 31 May 2019 / Revised: 3 July 2019 / Accepted: 5 July 2019 / Published: 7 July 2019
(This article belongs to the Special Issue Surgery for Spine Disease and Intractable Pain)
Coccidioidomycosis is a fungal infectious disease caused by the Coccidioides species endemic to Southwestern United States. Symptomatic patients typically present as community-acquired pneumonia. Uncommonly, in about 1% of infections, hematogenous extra pulmonary systemic dissemination involving skin, musculoskeletal system, and meninges occur. Disseminated spinal infection is treated with antifungal drugs and/or surgical treatment. A retrospective review of medical records at our institution was done between January 2009 to December 2018 and we present three cases of spinal coccidioidomycosis and review the current literature. Disseminated coccidioidomycosis can lead to spondylitis that can present as discitis or a localized spinal or paraspinal abscess. Spinal coccidioidomycosis is typically managed with antifungal treatments but can include surgical treatment in the setting poor response to medical therapy, intractable pain, presence of neurological deficits due to compression, or structural spinal instability. View Full-Text
Keywords: Coccidioidomycosis; spinal infection; spinal pain Coccidioidomycosis; spinal infection; spinal pain
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Ramanathan, D.; Sahasrabudhe, N.; Kim, E. Disseminated Coccidioidomycosis to the Spine—Case Series and Review of Literature. Brain Sci. 2019, 9, 160.

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