Prevalence and Clinical Significance of Symptoms at Ultra High Risk for Psychosis in Children and Adolescents with Obsessive–Compulsive Disorder: Is There an Association with Global, Role, and Social Functioning?
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Clinical Assessment
2.3. Statistical Analysis
3. Results
3.1. Sample Characteristics
3.2. Comparison between Groups
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Variable | Group 1 | Group 2 | p-Value |
---|---|---|---|
Patients OCD with UHR Symptoms | Patients OCD without UHR Symptoms | ||
Mean (SD) | Mean (SD) | ||
Age, years | 13.8 (2.6) | 13.0 (3.2) | 0.700 |
Education, years | 8.4 (2.7) | 7.6 (3.1) | 0.354 |
IQ level | 103 (18.6) | 103 (11.9) | 0.96 |
Number of psychiatric diagnoses | 1 (0.6) | 1 (0.9) | 0.500 |
Total CY-BOCS score | 23.6 (8.4) | 25.5 (8.0) | 0.473 |
SIPS Positive score | 7.8 (2.9) | 1.8 (1.4) | 0.000011 |
Total CDI score | 17.0 (10.5) | 11.9 (7.6) | 0.072 |
C-GAS | 45.9 (3.1) | 53.7 (8.5) | 0.00021 |
GF: Social | 3.7 (0.4) | 4.3 (0.8) | 0.0037621 |
GF: Role | 3.8 (0.4) | 4.3 (0.8) | 0.0063271 |
Group OCD with UHR Symptoms (n = 22) n (%) | Group OCD without UHR Symptoms (n = 29) n (%) | |||
---|---|---|---|---|
Obsessions | ||||
Aggressive, Sexual, Religious, Somatic | 11 | (50.0%) | 17 | (58.6%) |
Symmetry | 9 | (40.9%) | 9 | (31.0%) |
Contamination | 8 | (36.4%) | 12 | (41.4%) |
Hoarding | 1 | (4.5%) | 2 | (6.9%) |
Compulsions | ||||
Checking | 9 | (40.9%) | 12 | (41.4%) |
Repeating rituals, Counting, Ordering, Arranging | 10 | (45.5%) | 14 | (48.3%) |
Cleaning | 8 | (36.4%) | 13 | (44.8%) |
Hoarding, Collection | 1 | (4.5%) | 7 | (24.1%) |
Group OCD with UHR Symptoms (n = 22) n (%) | Group OCD without UHR Symptoms (n = 29) n (%) | |||
---|---|---|---|---|
Individual psychotherapy | 15 | (68.2%) | 10 | (34.5%) |
Familiar therapy | 0 | (0%) | 1 | (3.4%) |
Individual psychotherapy and Familiar therapy | 3 | (13.6%) | 4 | (13.8%) |
Individual psychotherapy and Parent training | 2 | (9.1%) | 2 | (6.9%) |
None | 2 | (9.1%) | 12 | (41.4%) |
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Averna, R.; Pontillo, M.; Demaria, F.; Armando, M.; Santonastaso, O.; Pucciarini, M.L.; Tata, M.C.; Mancini, F.; Vicari, S. Prevalence and Clinical Significance of Symptoms at Ultra High Risk for Psychosis in Children and Adolescents with Obsessive–Compulsive Disorder: Is There an Association with Global, Role, and Social Functioning? Brain Sci. 2018, 8, 181. https://doi.org/10.3390/brainsci8100181
Averna R, Pontillo M, Demaria F, Armando M, Santonastaso O, Pucciarini ML, Tata MC, Mancini F, Vicari S. Prevalence and Clinical Significance of Symptoms at Ultra High Risk for Psychosis in Children and Adolescents with Obsessive–Compulsive Disorder: Is There an Association with Global, Role, and Social Functioning? Brain Sciences. 2018; 8(10):181. https://doi.org/10.3390/brainsci8100181
Chicago/Turabian StyleAverna, Roberto, Maria Pontillo, Francesco Demaria, Marco Armando, Ornella Santonastaso, Maria Laura Pucciarini, Maria Cristina Tata, Francesco Mancini, and Stefano Vicari. 2018. "Prevalence and Clinical Significance of Symptoms at Ultra High Risk for Psychosis in Children and Adolescents with Obsessive–Compulsive Disorder: Is There an Association with Global, Role, and Social Functioning?" Brain Sciences 8, no. 10: 181. https://doi.org/10.3390/brainsci8100181
APA StyleAverna, R., Pontillo, M., Demaria, F., Armando, M., Santonastaso, O., Pucciarini, M. L., Tata, M. C., Mancini, F., & Vicari, S. (2018). Prevalence and Clinical Significance of Symptoms at Ultra High Risk for Psychosis in Children and Adolescents with Obsessive–Compulsive Disorder: Is There an Association with Global, Role, and Social Functioning? Brain Sciences, 8(10), 181. https://doi.org/10.3390/brainsci8100181