Next Article in Journal
Syntactic and Semantic Influences on the Time Course of Relative Clause Processing: The Role of Language Dominance
Previous Article in Journal
Neural Interruption by Unilateral Labyrinthectomy Biases the Directional Preference of Otolith-Related Vestibular Neurons
 
 
Article

Computerized Cognitive Training (CCT) versus Yoga Impact on 12 Month Post Intervention Cognitive Outcome in Individuals with Mild Cognitive Impairment

1
Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE 68131, USA
2
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA
3
Department of Psychiatry and Psychology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
4
Department of Psychiatry and Psychology, Mayo Clinic Health System, La Crosse, WI 54601, USA
5
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98108, USA
6
Division of Clinical Trials and Biostatistics, Mayo Clinic Florida, Jacksonville, FL 32224, USA
7
Department of Psychiatry and Psychology, Mayo Clinic Florida, Jacksonville, FL 32224, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Stefano Barlati
Brain Sci. 2021, 11(8), 988; https://doi.org/10.3390/brainsci11080988
Received: 7 June 2021 / Revised: 14 July 2021 / Accepted: 21 July 2021 / Published: 27 July 2021
There is currently limited and mixed evidence for the cognitive benefits of Computerized Cognitive Training (CCT) and yoga in persons with Mild Cognitive Impairment (pwMCI). The objective of this study was to investigate the benefit of computerized cognitive training (CCT) vs. physical (yoga) intervention on cognitive abilities. Participants in this study were part of the larger Mayo Clinic’s Healthy Action to Benefit Independence and Thinking (HABIT) program comparative effectiveness trial. The HABIT program is designed for pwMCI and their care partner and consists of five behavioral interventions: CCT, Memory Support System-Calendar (MSS-Calendar), wellness education, support groups, and yoga. The subtractive study design randomly withheld one of the interventions for a total of five study arms. Longitudinal mixed-effects regression models were used to investigate the hypothesis that CCT and yoga has a greater positive impact on psychomotor and basic attention abilities at 12 months post-intervention as compared to the other HABIT interventions. Findings showed CCT had a positive impact compared to yoga on the Cogstate psychomotor/attention composite at 12 months post-intervention (ES = 0.54; unadjusted p value = 0.007, adjusted p value = 0.021). The impact of yoga or combining CCT with yoga did not show statistically significant improvement. Continued CCT practice at home showed further benefit on psychomotor/attention at 12 months post-intervention. There was no significant benefit of CCT or yoga on Cogstate learning/working memory composite. View Full-Text
Keywords: behavioral interventions; computerized cognitive training (CCT); physical exercise; yoga; mild cognitive impairment (MCI); cognitive enrichment; clinical trial behavioral interventions; computerized cognitive training (CCT); physical exercise; yoga; mild cognitive impairment (MCI); cognitive enrichment; clinical trial
Show Figures

Figure 1

MDPI and ACS Style

Phatak, V.S.; Smith, G.E.; Locke, D.; Shandera-Ochsner, A.; Dean, P.M.; Ball, C.; Gutierrez, G.; Chandler, M.J. Computerized Cognitive Training (CCT) versus Yoga Impact on 12 Month Post Intervention Cognitive Outcome in Individuals with Mild Cognitive Impairment. Brain Sci. 2021, 11, 988. https://doi.org/10.3390/brainsci11080988

AMA Style

Phatak VS, Smith GE, Locke D, Shandera-Ochsner A, Dean PM, Ball C, Gutierrez G, Chandler MJ. Computerized Cognitive Training (CCT) versus Yoga Impact on 12 Month Post Intervention Cognitive Outcome in Individuals with Mild Cognitive Impairment. Brain Sciences. 2021; 11(8):988. https://doi.org/10.3390/brainsci11080988

Chicago/Turabian Style

Phatak, Vaishali S., Glenn E. Smith, Dona Locke, Anne Shandera-Ochsner, Pamela M. Dean, Colleen Ball, Gianna Gutierrez, and Melanie J. Chandler. 2021. "Computerized Cognitive Training (CCT) versus Yoga Impact on 12 Month Post Intervention Cognitive Outcome in Individuals with Mild Cognitive Impairment" Brain Sciences 11, no. 8: 988. https://doi.org/10.3390/brainsci11080988

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop