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Article

The Effects of 4 Weeks of Chiropractic Spinal Adjustments on Motor Function in People with Stroke: A Randomized Controlled Trial

1
Centre for Chiropractic Research, New Zealand College of Chiropractic, Auckland 1060, New Zealand
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Faculty of Health & Environmental Sciences, Health & Rehabilitation Research Institute, AUT University, Auckland 0627, New Zealand
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Department of Health Science and Technology, Aalborg University, 9220 Aalborg, Denmark
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Faculty of Rehabilitation and Allied Health Sciences and Department of Biomedical Engineering, Riphah International University, Islamabad 46000, Pakistan
*
Author to whom correspondence should be addressed.
Academic Editor: Michelle Ploughman
Brain Sci. 2021, 11(6), 676; https://doi.org/10.3390/brainsci11060676
Received: 23 March 2021 / Revised: 19 May 2021 / Accepted: 19 May 2021 / Published: 21 May 2021
Chiropractic spinal adjustments have been shown to result in short-term increases in muscle strength in chronic stroke patients, however, the effect of longer-term chiropractic spinal adjustments on people with chronic stroke is unknown. This exploratory study assessed whether 4 weeks of chiropractic spinal adjustments, combined with physical therapy (chiro + PT), had a greater impact than sham chiropractic with physical therapy (sham + PT) did on motor function (Fugl Meyer Assessment, FMA) in 63 subacute or chronic stroke patients. Secondary outcomes included health-related quality of life and other measures of functional mobility and disability. Outcomes were assessed at baseline, 4 weeks (post-intervention), and 8 weeks (follow-up). Data were analyzed using linear mixed-effects models or generalized linear mixed models. A post-hoc responder analysis was performed to investigate the clinical significance of findings. At 4 weeks, there was a larger effect of chiro + PT, compared with sham + PT, on the FMA (difference = 6.1, p = 0.04). The responder analysis suggested the improvements in motor function seen following chiropractic spinal adjustments may have been clinically significant. There was also a robust improvement in both groups in most measures from baseline to the 4- and 8-week assessments, but between-group differences were no longer significant at the 8-week assessment. Four weeks of chiro + PT resulted in statistically significant improvements in motor function, compared with sham + PT, in people with subacute or chronic stroke. These improvements appear to be clinically important. Further trials, involving larger group sizes and longer follow-up and intervention periods, are required to corroborate these findings and further investigate the impacts of chiropractic spinal adjustments on motor function in post-stroke survivors. ClinicalTrials.gov Identifier NCT03849794. View Full-Text
Keywords: stroke; motor function; chiropractic spinal adjustment; physical therapy; health-related quality of life; recovery of function stroke; motor function; chiropractic spinal adjustment; physical therapy; health-related quality of life; recovery of function
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MDPI and ACS Style

Holt, K.; Niazi, I.K.; Amjad, I.; Kumari, N.; Rashid, U.; Duehr, J.; Navid, M.S.; Shafique, M.; Haavik, H. The Effects of 4 Weeks of Chiropractic Spinal Adjustments on Motor Function in People with Stroke: A Randomized Controlled Trial. Brain Sci. 2021, 11, 676. https://doi.org/10.3390/brainsci11060676

AMA Style

Holt K, Niazi IK, Amjad I, Kumari N, Rashid U, Duehr J, Navid MS, Shafique M, Haavik H. The Effects of 4 Weeks of Chiropractic Spinal Adjustments on Motor Function in People with Stroke: A Randomized Controlled Trial. Brain Sciences. 2021; 11(6):676. https://doi.org/10.3390/brainsci11060676

Chicago/Turabian Style

Holt, Kelly, Imran K. Niazi, Imran Amjad, Nitika Kumari, Usman Rashid, Jens Duehr, Muhammad S. Navid, Muhammad Shafique, and Heidi Haavik. 2021. "The Effects of 4 Weeks of Chiropractic Spinal Adjustments on Motor Function in People with Stroke: A Randomized Controlled Trial" Brain Sciences 11, no. 6: 676. https://doi.org/10.3390/brainsci11060676

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