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Article

Effects of Physical Exercise on Cognition and Telomere Length in Healthy Older Women

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Department of Nursery and Physiotherapy, Faculty of Nursery and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain
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Department of Basic Psychology, Psychobiology and Methodology, Faculty of Psychology, University of Salamanca, 37005 Salamanca, Spain
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Department of Statistics, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain
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Department of Medicine, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain
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Author to whom correspondence should be addressed.
Academic Editor: Eric S. Drollette
Brain Sci. 2021, 11(11), 1417; https://doi.org/10.3390/brainsci11111417
Received: 4 October 2021 / Revised: 18 October 2021 / Accepted: 26 October 2021 / Published: 27 October 2021
Background: Physical exercise is an effective measure for preventing the onset of cognitive decline and has a direct influence on the aging process. The purpose of this study was to assess the effect of a 6-month physical exercise program on cognition and telomere length in adults over 65 years of age. Method: Seventy-four healthy women were separated into two groups: 41 were included in the intervention group (IG) (72.70 ± 4.127 years and 8.18 ± 1.551 years of education) and 33 in the control group (CG) (71.21 ± 4.127 years and 8.42 ± 2.562). The participants included within the IG carried out three sessions of physical exercise per week for six months. Cognitive function was assessed using the Mini-Mental State Examination (MMSE), the Stroop test and the Trail Making Test (TMT). Saliva samples were taken and analyzed and relative telomere length was calculated. Those conducting the analysis were blind to the group to which the participants had been assigned. Results: An improvement was observed in global cognitive function, in both attentional and executive functions, in the group of adults doing physical exercise as compared to the control group. Six months after the physical exercise program had finished, relative telomere length was found to have increased in the participants in the intervention group. Conclusion: Physical exercise programs can lead to an improvement in both cognitive functions and telomere length. View Full-Text
Keywords: exercise; cognition; adults; telomerase; ageing exercise; cognition; adults; telomerase; ageing
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MDPI and ACS Style

Sánchez-González, J.L.; Sánchez-Rodríguez, J.L.; Martín-Vallejo, J.; Martel-Martel, A.; González-Sarmiento, R. Effects of Physical Exercise on Cognition and Telomere Length in Healthy Older Women. Brain Sci. 2021, 11, 1417. https://doi.org/10.3390/brainsci11111417

AMA Style

Sánchez-González JL, Sánchez-Rodríguez JL, Martín-Vallejo J, Martel-Martel A, González-Sarmiento R. Effects of Physical Exercise on Cognition and Telomere Length in Healthy Older Women. Brain Sciences. 2021; 11(11):1417. https://doi.org/10.3390/brainsci11111417

Chicago/Turabian Style

Sánchez-González, Juan L., Juan L. Sánchez-Rodríguez, Javier Martín-Vallejo, Abel Martel-Martel, and Rogelio González-Sarmiento. 2021. "Effects of Physical Exercise on Cognition and Telomere Length in Healthy Older Women" Brain Sciences 11, no. 11: 1417. https://doi.org/10.3390/brainsci11111417

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