Next Article in Journal
Dysregulated Wnt Signalling in the Alzheimer’s Brain
Next Article in Special Issue
The Effect of Non-Personalised Tips on the Continued Use of Self-Monitoring mHealth Applications
Previous Article in Journal
Chronic Ethanol Exposure during Adolescence Increases Voluntary Ethanol Consumption in Adulthood in Female Sprague Dawley Rats
Previous Article in Special Issue
Contemporary Review of Smartphone Apps for Tinnitus Management and Treatment
Open AccessReview

Auditory Brainstem Responses (ABR) of Rats during Experimentally Induced Tinnitus: Literature Review

1
Department of Otorhinolaryngology, Head and Neck Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany
2
Faculty of Medicine and Health Sciences, University of Zielona Gora, 65-046 Zielona Gora, Poland
*
Author to whom correspondence should be addressed.
Brain Sci. 2020, 10(12), 901; https://doi.org/10.3390/brainsci10120901
Received: 20 October 2020 / Revised: 16 November 2020 / Accepted: 21 November 2020 / Published: 24 November 2020
(This article belongs to the Special Issue Tinnitus Subtyping)
Tinnitus is a subjective phantom sound perceived only by the affected person and a symptom of various auditory and non-auditory conditions. The majority of methods used in clinical and basic research for tinnitus diagnosis are subjective. To better understand tinnitus-associated changes in the auditory system, an objective technique measuring auditory sensitivity—the auditory brainstem responses (ABR)—has been suggested. Therefore, the present review aimed to summarize ABR’s features in a rat model during experimentally induced tinnitus. PubMed, Web of Science, Science Direct, and Scopus databanks were searched using Medical Subject Heading (MeSH) terms: auditory brainstem response, tinnitus, rat. The search identified 344 articles, and 36 of them were selected for the full-text analyses. The experimental protocols and results were evaluated, and the gained knowledge was synthesized. A high level of heterogeneity between the studies was found regarding all assessed areas. The most consistent finding of all studies was a reduction in the ABR wave I amplitude following exposure to noise and salicylate. Simultaneously, animals with salicylate-induced but not noise-induced tinnitus had an increased amplitude of wave IV. Furthermore, the present study identified a need to develop a consensus experimental ABR protocol applied in future tinnitus studies using the rat model. View Full-Text
Keywords: auditory brainstem response (ABR); tinnitus; animal model; rat auditory brainstem response (ABR); tinnitus; animal model; rat
Show Figures

Figure 1

MDPI and ACS Style

Domarecka, E.; Olze, H.; Szczepek, A.J. Auditory Brainstem Responses (ABR) of Rats during Experimentally Induced Tinnitus: Literature Review. Brain Sci. 2020, 10, 901. https://doi.org/10.3390/brainsci10120901

AMA Style

Domarecka E, Olze H, Szczepek AJ. Auditory Brainstem Responses (ABR) of Rats during Experimentally Induced Tinnitus: Literature Review. Brain Sciences. 2020; 10(12):901. https://doi.org/10.3390/brainsci10120901

Chicago/Turabian Style

Domarecka, Ewa; Olze, Heidi; Szczepek, Agnieszka J. 2020. "Auditory Brainstem Responses (ABR) of Rats during Experimentally Induced Tinnitus: Literature Review" Brain Sci. 10, no. 12: 901. https://doi.org/10.3390/brainsci10120901

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop