Next Article in Journal
Ultra-Low-Loss Silicon Waveguides for Heterogeneously Integrated Silicon/III-V Photonics
Previous Article in Journal
Fatigue Behavior of Prestressed Concrete Beam for Straddle-Type Monorail Tracks
Article Menu
Issue 7 (July) cover image

Export Article

Open AccessArticle
Appl. Sci. 2018, 8(7), 1138; https://doi.org/10.3390/app8071138

Signal Intensity of Contrast Enhancement according to TE in 3.0T MRI T1 Imaging

1
Department of Bio-Medical Science, Korea University, 145 Anam-ro Sungbuk-ku, Seoul 02841, Korea
2
Department of Radiological Science & Physical Medicine, Eulji University, 553 Sanseong-daero Soojung-ku Sungnam-city, Kyunggi-do 13135, Korea
*
Authors to whom correspondence should be addressed.
Received: 12 June 2018 / Revised: 6 July 2018 / Accepted: 11 July 2018 / Published: 13 July 2018
(This article belongs to the Section Optics and Lasers)
Full-Text   |   PDF [4723 KB, uploaded 13 July 2018]   |  

Abstract

Normal body tissue or lesion characteristics in T1 images have been evaluated; however, how external parameters effect the change in signal intensity by gadolinium-based contrast agent remains unknown. We investigated how contrast enhancement changed according to echo time (TE) in 3.0T magnetic resonance (MR) T1 imaging and determined the optimal settings for TE in contrast-enhanced T1 imaging. Since there are no guidelines regarding parameters for T1 enhancement when using MR-contrast agents, we analyzed results from varying TEs (between 25 and 7 msec) in both a phantom and clinical study. We obtained the following results: contrast percentage of fat to saline increased from 740.0–1003.6%, response start point increased from 30–90 mmol, max peak signal intensity increased from 1771–2425 a.u., max peak point increased from 2–4 mmol, enhancement percentage of the max peak signal intensity (MPSI) to saline increased from 1671.0–2065.2%, the average of SI on each mol as TE increased from 600.8–996.6 a.u., the average of SI as TE on each molar concentration increased from 378–845 a.u., the AEPSS increased from 44.3–140.3%, and the AEPSC increased from 224.3–647.8%. We confirmed that TE can affect contrast enhancement, and the lowest TE has faster and higher effects on contrast enhancement. View Full-Text
Keywords: 3.0T MRI; contrast enhancement; gadoteridol; contrast media; echo time; T1 imaging 3.0T MRI; contrast enhancement; gadoteridol; contrast media; echo time; T1 imaging
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Jeong, H.K.; Lee, K.H.; Kim, M.H.; Kim, S.H.; Kim, M.G.; Kim, H.C. Signal Intensity of Contrast Enhancement according to TE in 3.0T MRI T1 Imaging. Appl. Sci. 2018, 8, 1138.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Appl. Sci. EISSN 2076-3417 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top