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Open AccessArticle

Numerical Investigation of the Effects of Prosthetic Aortic Valve Design on Aortic Hemodynamic Characteristics

1
School of Energy and Power Engineering, Xi’an Jiaotong University, Xi’an 710049, China
2
School of Sciences, Xi’an University of Technology, Xi’an 710054, China
3
School of Mechanical Engineering, Xi’an Shiyou University, Xi’an 710065, China
4
School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore
5
Department of Chemical and Materials Engineering, National University of Kaohsiung, No. 700, Kaohsiung University Rd., Nan-Tzu District, Kaohsiung 811, Taiwan
*
Authors to whom correspondence should be addressed.
Appl. Sci. 2020, 10(4), 1396; https://doi.org/10.3390/app10041396
Received: 26 December 2019 / Revised: 7 February 2020 / Accepted: 14 February 2020 / Published: 19 February 2020
(This article belongs to the Special Issue Intelligent System Innovation)
The superior performance of single-point attached commissures (SPAC) molded valve design has been validated by several numerical, in vitro and in vivo animal studies. However, the impacts of the SPAC molded valve design on aortic hemodynamic environments are yet to be investigated. In this study, multiscale computational models were prepared by virtually implanting prosthetic aortic valves with SPAC tubular, SPAC molded and conventional designs into a patient-specific aorta, respectively. The impacts of the valve designs on efferent flow distribution, flow pattern and hemodynamic characteristics in the aorta were numerically investigated. The results showed that despite the overall flow phenomena being similar, the SPAC tubular valve exhibited a suboptimal performance in terms of higher spatially averaged wall shear stress (SAWSS) in ascending aorta (AAo), higher helix grade, stronger secondary flow mean secondary velocity in descending aorta, as well as more complex vortex distribution. The results from the current study extend the understanding of hemodynamic impacts of the valve designs, which would further benefit the optimization of the prosthetic aortic valve. View Full-Text
Keywords: prosthetic aortic valve; single point attached commissures; helical flow; hemodynamic environments; wall shear stress; vortex prosthetic aortic valve; single point attached commissures; helical flow; hemodynamic environments; wall shear stress; vortex
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MDPI and ACS Style

Zhu, G.-Y.; Huang, H.; Su, Y.-L.; Yeo, J.-H.; Shen, X.-Q.; Yang, C.-F. Numerical Investigation of the Effects of Prosthetic Aortic Valve Design on Aortic Hemodynamic Characteristics. Appl. Sci. 2020, 10, 1396. https://doi.org/10.3390/app10041396

AMA Style

Zhu G-Y, Huang H, Su Y-L, Yeo J-H, Shen X-Q, Yang C-F. Numerical Investigation of the Effects of Prosthetic Aortic Valve Design on Aortic Hemodynamic Characteristics. Applied Sciences. 2020; 10(4):1396. https://doi.org/10.3390/app10041396

Chicago/Turabian Style

Zhu, Guang-Yu; Huang, Hai; Su, Ya-Li; Yeo, Joon-Hock; Shen, Xiao-Qin; Yang, Cheng-Fu. 2020. "Numerical Investigation of the Effects of Prosthetic Aortic Valve Design on Aortic Hemodynamic Characteristics" Appl. Sci. 10, no. 4: 1396. https://doi.org/10.3390/app10041396

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