Mast Cells, Astrocytes, Arachidonic Acid: Do They Play a Role in Depression?
Abstract
:1. Introduction
2. Arachidonic Acid Sources
3. Sphingolipids and Sphingomyelinase Role in Depression
4. Mast Cells and Depression
5. Cross-Talk between Mast Cells, Astrocytes and Microglia
6. Serotonin and Depression
7. Conclusions and Perspectives
Author Contributions
Funding
Conflicts of Interest
Abbreviations
AA | arachidonic acid |
BD | bipolar disorder |
CNS | central nervous system |
COX | cyclo-oxygenase |
DHA | docosahexaenoic acid |
EC | endocrine cell |
5-HT | 5-hydroxytryptamine, serotonin |
HETE | hydroxyeicosatetraenoic acid |
LA | linoleic acid |
LD | lipid droplet |
LOX | lipooxygenase |
MC | mast cell |
MD | major depression |
PA | palmitic acid |
PC | phosphatidylcholine |
PE | phosphatidylethanolamine |
PGE | prostaglandin |
PL | phospholipid |
PLA2 | phospholipase A2 |
PUFA | polyunsaturated fatty acid |
SCFAs | short-chain fatty acids |
SP | substance |
TG | triglyceride |
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Traina, G.; Cocchi, M. Mast Cells, Astrocytes, Arachidonic Acid: Do They Play a Role in Depression? Appl. Sci. 2020, 10, 3455. https://doi.org/10.3390/app10103455
Traina G, Cocchi M. Mast Cells, Astrocytes, Arachidonic Acid: Do They Play a Role in Depression? Applied Sciences. 2020; 10(10):3455. https://doi.org/10.3390/app10103455
Chicago/Turabian StyleTraina, Giovanna, and Massimo Cocchi. 2020. "Mast Cells, Astrocytes, Arachidonic Acid: Do They Play a Role in Depression?" Applied Sciences 10, no. 10: 3455. https://doi.org/10.3390/app10103455