A Comparison of Diets Supplemented with a Feed Additive Containing Organic Acids, Cinnamaldehyde and a Permeabilizing Complex, or Zinc Oxide, on Post-Weaning Diarrhoea, Selected Bacterial Populations, Blood Measures and Performance in Weaned Pigs Experimentally Infected with Enterotoxigenic E. coli

Stensland, Ingunn; Kim, Jae Cheol; Bowring, Bethany; Collins, Alison M.; Mansfield, Josephine P.; Pluske, John R.

doi:10.3390/ani5040403

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A Comparison of Diets Supplemented with a Feed Additive Containing Organic Acids, Cinnamaldehyde and a Permeabilizing Complex, or Zinc Oxide, on Post-Weaning Diarrhoea, Selected Bacterial Populations, Blood Measures and Performance in Weaned Pigs Experimentally Infected with Enterotoxigenic E. coli ^†

¹,

^2,‡,

^3,‡,

^3,‡

Josephine P. Mansfield

^1,‡ and

John R. Pluske

^1,*

School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia

Pork Innovation, Department of Agriculture and Food Western Australia, South Perth, WA 6150, Australia

New South Wales Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, PMB 4008, Narellan 2567, Australia

Author to whom correspondence should be addressed.

^†

Aspects of this work have been published as: Stensland, I.; Kim, J.C.; Mansfield, J.; Pluske, J.R. Differential effects of zinc oxide and a preparation of organic acids and an essential oil on post-weaning diarrhoea. Anim. Prod. Sci. 2015, 55, 1571.

^‡

These authors contributed equally to this work.

Academic Editor: Clive J. C. Phillips

Animals 2015, 5(4), 1147-1168; https://doi.org/10.3390/ani5040403

Received: 7 September 2015 / Revised: 9 November 2015 / Accepted: 13 November 2015 / Published: 23 November 2015

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Abstract

The effects of feeding a diet supplemented with zinc oxide (ZnO) or a blend of organic acids, cinnamaldehyde and a permeabilizing complex (OACP) on post-weaning diarrhoea (PWD) and performance in pigs infected with enterotoxigenic E. coli (ETEC) were examined. Additionally, changes in selected bacterial populations and blood measures were assessed. A total of 72 pigs weaned at 22 d of age and weighing 7.2 ± 1.02 kg (mean ± SEM) was used. Treatments were: base diet (no antimicrobial compounds); base diet + 3 g ZnO/kg; base diet + 1.5 g OACP/kg. Dietary treatments started on the day of weaning and were fed ad libitum for 3 weeks. All pigs were infected with an F4 ETEC on d 4, 5 and 6 after weaning. The incidence of PWD was lower in pigs fed ZnO ( p = 0.026). Overall, pigs fed ZnO grew faster ( p = 0.013) and ate more ( p = 0.004) than the base diet-fed pigs, with OACP-fed pigs performing the same ( p > 0.05) as both the ZnO- and base diet-fed pigs. Feed conversion ratio was similar for all diets ( p > 0.05). The percentage of E. coli with F4 fimbriae was affected a day by treatment interaction ( p = 0.037), with more E. coli with F4 fimbriae found in pigs fed ZnO on d 11 ( p = 0.011) compared to base diet-fed pigs. Only significant time effects ( p < 0.05) occurred for blood measures. Under the conditions of this study, inclusion of OACP gave statistically similar production responses to pigs fed ZnO, however pigs fed ZnO had less PWD compared to OACP- and the base diet-fed pigs. View Full-Text

Keywords: cinnamaldehyde; enterotoxigenic E. coli; organic acids; post-weaning diarrhoea; pigs; zinc oxide; permeabilizing complex

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MDPI and ACS Style

Stensland, I.; Kim, J.C.; Bowring, B.; Collins, A.M.; Mansfield, J.P.; Pluske, J.R. A Comparison of Diets Supplemented with a Feed Additive Containing Organic Acids, Cinnamaldehyde and a Permeabilizing Complex, or Zinc Oxide, on Post-Weaning Diarrhoea, Selected Bacterial Populations, Blood Measures and Performance in Weaned Pigs Experimentally Infected with Enterotoxigenic E. coli . Animals 2015, 5, 1147-1168. https://doi.org/10.3390/ani5040403

AMA Style

Stensland I, Kim JC, Bowring B, Collins AM, Mansfield JP, Pluske JR. A Comparison of Diets Supplemented with a Feed Additive Containing Organic Acids, Cinnamaldehyde and a Permeabilizing Complex, or Zinc Oxide, on Post-Weaning Diarrhoea, Selected Bacterial Populations, Blood Measures and Performance in Weaned Pigs Experimentally Infected with Enterotoxigenic E. coli . Animals. 2015; 5(4):1147-1168. https://doi.org/10.3390/ani5040403

Chicago/Turabian Style

Stensland, Ingunn, Jae C. Kim, Bethany Bowring, Alison M. Collins, Josephine P. Mansfield, and John R. Pluske. 2015. "A Comparison of Diets Supplemented with a Feed Additive Containing Organic Acids, Cinnamaldehyde and a Permeabilizing Complex, or Zinc Oxide, on Post-Weaning Diarrhoea, Selected Bacterial Populations, Blood Measures and Performance in Weaned Pigs Experimentally Infected with Enterotoxigenic E. coli " Animals 5, no. 4: 1147-1168. https://doi.org/10.3390/ani5040403

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