Review Reports

Round 1

Reviewer 1 Report

See attached word document for comments on this manuscript. 

Comments for author File: Comments.pdf

Author Response

We thank you for your thorough review and comments.

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

This is a very interesting topic, but the introduction fails in justifying why Lactobacillus gasseri, could be an accurate solution to treat obesity. The number of dogs, enrolled in this study, is quite low and the population looks quite unusual. When we compare the breeds, mentioned in Table 1 and the initial weights in Table 3, we face some surprise. It is well understood that we treat obese dogs, but a Yorkshire Terrier of 8.15 kg is a very severe case. A Table with individual data would have been preferable. It is more a caseload, than a controlled study, and such work gets significant improvement with sharing individual data and evolution. By the way, a description of the diet would have been interesting and could provide valuable data for the discussion about the evolution of the microbiome. The statistics are very poorly detailed, especially with explaining whet is compared (I guess it is the difference between week 0 and week10). The discussion does not provide any clarification about the justification of the treatment. Since the idea comes from human medicine, it would have been interesting to compare the evolution in human and dog patients, to discuss the evolution of the weight and microbiome.

Author Response

We thank you for your thorough review and comments.

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 1 Report

See attached document with comments 

Comments for author File: Comments.pdf

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

Thank you for improving significantly your paper. In my opinion, it would be better to modify the title and present it as a Preliminary or Pilote study.

Author Response

We really thank you for your efforts and comments.

We have changed the title and presented as pilot study.