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Selenium and Dogs: A Systematic Review

Department of Animal Breeding, Animal Nutrition and Biochemistry, University of Veterinary and Pharmaceutical Sciences, 61242 Brno, Czech Republic
Department of Animal Protection and Welfare and Veterinary Public Health, University of Veterinary and Pharmaceutical Sciences, 61242 Brno, Czech Republic
Author to whom correspondence should be addressed.
Academic Editor: Dennis Jewell
Animals 2021, 11(2), 418;
Received: 28 January 2021 / Revised: 1 February 2021 / Accepted: 3 February 2021 / Published: 6 February 2021
(This article belongs to the Section Animal Nutrition)
Selenium is a microelement which intake is essential for correct function of the metabolism. In a dog’s body, it is important, for example, for its antioxidant function, its role in thyroid metabolism, synthesis of DNA, or reproduction. It seems that it also plays an important role in prevention and treatment of cancer. While nutritional recommendations for its content in commercial dog food exist, they do not differ between types of food, such as kibble versus canned food. Home-made diets have lower content of selenium than commercial food, but selenium may have greater bioavailability from raw products than processed ones. Moreover, reference values for its levels in dog’s serum, plasma, full blood, and tissues are not very well defined.
The intent of this review is to summarize the knowledge about selenium and its function in a dog’s body. For this purpose, systematic literature search was conducted. For mammals, including dogs, a balanced diet and sufficient intake of selenium are important for correct function of metabolism. As for selenium poisoning, there are no naturally occurring cases known. Nowadays, we do not encounter clinical signs of its deficiency either, but it can be subclinical. For now, the most reliable method of assessing selenium status of a dog is measuring serum or plasma levels. Levels in full blood can be measured too, but there are no reference values. The use of glutathione peroxidase as an indirect assay is questionable in canines. Commercial dog food manufactures follow recommendations for minimal and maximal selenium levels and so dogs fed commercial diets should have balanced intake of selenium. For dogs fed home-made diets, complex data are missing. However, subclinical deficiency seems to affect, for example, male fertility or recovery from parasitical diseases. Very interesting is the role of selenium in prevention and treatment of cancer. View Full-Text
Keywords: nutritional recommendations; blood; serum; Se biomarkers; Canis familiaris nutritional recommendations; blood; serum; Se biomarkers; Canis familiaris
MDPI and ACS Style

Zentrichová, V.; Pechová, A.; Kovaříková, S. Selenium and Dogs: A Systematic Review. Animals 2021, 11, 418.

AMA Style

Zentrichová V, Pechová A, Kovaříková S. Selenium and Dogs: A Systematic Review. Animals. 2021; 11(2):418.

Chicago/Turabian Style

Zentrichová, Viola, Alena Pechová, and Simona Kovaříková. 2021. "Selenium and Dogs: A Systematic Review" Animals 11, no. 2: 418.

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