Effects of Long-Term Selection in the Border Collie Dog Breed: Inbreeding Purge of Canine Hip and Elbow Dysplasia
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Data Collection
- Individual identity number;
- Male parent;
- Female parent;
- Date of birth;
- Country of birth (i.e., country of origin).
- The minimum age of the dog for radiographic imaging is 1 year;
- The dog must be identified by a microchip;
- All dogs should be sufficiently sedated or anesthetized during the procedure to relax all muscles.
2.2. Data Analysis
- F_W: Inbreeding coefficient described by [31].
- F_BAL: Ancestral inbreeding coefficient, determined as the cumulative proportion of the genome exposed to inbreeding effects [26]. F_BAL was created to test the magnitude and effectiveness of inbreeding depression as the extent to which individual’s ancestors had been subjected to inbreeding.
- F_KAL: Inbreeding coefficient defined by [17]. The probability that alleles had been autozygous (IBD) in the previous generation at least once, where the common ancestor was presented on both sides of the pedigree.
- F_KAL_NEW: Kalinowski new inbreeding coefficient, described as alleles IBD, was inbred for the first time [17].
3. Results
3.1. Results for Purging in Canine Hip Dysplasia
3.2. Results of Purging in Canine Elbow Dysplasia
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Hip Rating | Category Name | Hip Scores |
---|---|---|
A | Excellent | 0 |
B | Borderline | 1 |
C | Mild | 2 |
D | Moderate | 3 |
E | Severe | 4 |
Elbow Rating | Category |
---|---|
0 | Normal: No sign of arthrosis |
1 | Slight: Osteophytes, less than 2 mm |
2 | Medium: Osteophytes from 2 to 5 mm |
3 | Severe: Osteophytes, more than 5 mm |
Model | Component Models | AIC | |
---|---|---|---|
CED | CHD | ||
1 | F_w + F_BAL | 95.56 | 2243.45 |
2 | F_KAL + F_KAL_New | 92.82 | 2250.16 |
Variables | CED | CHD |
---|---|---|
Pr(>|z|) | Pr(>|z|) | |
F_W | 0.802 | 0.009 ** |
F_BAL | 0.425 | 0.003 ** |
F_KAL | 0.001 *** | 0.003 ** |
F_KAL_NEW | 0.011 * | 0.444 |
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Ács, V.; Kövér, G.; Farkas, J.; Bokor, Á.; Nagy, I. Effects of Long-Term Selection in the Border Collie Dog Breed: Inbreeding Purge of Canine Hip and Elbow Dysplasia. Animals 2020, 10, 1743. https://doi.org/10.3390/ani10101743
Ács V, Kövér G, Farkas J, Bokor Á, Nagy I. Effects of Long-Term Selection in the Border Collie Dog Breed: Inbreeding Purge of Canine Hip and Elbow Dysplasia. Animals. 2020; 10(10):1743. https://doi.org/10.3390/ani10101743
Chicago/Turabian StyleÁcs, Virág, György Kövér, János Farkas, Árpád Bokor, and István Nagy. 2020. "Effects of Long-Term Selection in the Border Collie Dog Breed: Inbreeding Purge of Canine Hip and Elbow Dysplasia" Animals 10, no. 10: 1743. https://doi.org/10.3390/ani10101743