Next Article in Journal
In Vitro Anti-Biofilm Activity of Bacteriophage K (ATCC 19685-B1) and Daptomycin against Staphylococci
Next Article in Special Issue
Behaviour of Listeria monocytogenes and Natural Microflora during the Manufacture of Riojano Chorizo (Spanish Dry Cured Sausage)
Previous Article in Journal
Pediococcus Pentosaceus from the Sweet Potato Fermented Ger-Minated Brown Rice Can Inhibit Type I Hypersensitivity in RBL-2H3 Cell and BALB/c Mice Models
Previous Article in Special Issue
Novel Sequence Types of Listeria monocytogenes of Different Origin Obtained in the Republic of Serbia
Review

Application of Whole Genome Sequencing to Aid in Deciphering the Persistence Potential of Listeria monocytogenes in Food Production Environments

1
UCD-Centre for Food Safety, School of Public Health, Physiotherapy & Sports Science, University College Dublin, D04 N2E5 Dublin, Ireland
2
Department of Microbiology, St. Vincent’s University Hospital, D04 T6F4 Dublin, Ireland
*
Author to whom correspondence should be addressed.
Academic Editor: Elena González-Fandos
Microorganisms 2021, 9(9), 1856; https://doi.org/10.3390/microorganisms9091856
Received: 2 June 2021 / Revised: 23 August 2021 / Accepted: 25 August 2021 / Published: 31 August 2021
(This article belongs to the Special Issue An Update on Listeria monocytogenes)
Listeria monocytogenes is the etiological agent of listeriosis, a foodborne illness associated with high hospitalizations and mortality rates. This bacterium can persist in food associated environments for years with isolates being increasingly linked to outbreaks. This review presents a discussion of genomes of Listeria monocytogenes which are commonly regarded as persisters within food production environments, as well as genes which are involved in mechanisms aiding this phenotype. Although criteria for the detection of persistence remain undefined, the advent of whole genome sequencing (WGS) and the development of bioinformatic tools have revolutionized the ability to find closely related strains. These advancements will facilitate the identification of mechanisms responsible for persistence among indistinguishable genomes. In turn, this will lead to improved assessments of the importance of biofilm formation, adaptation to stressful conditions and tolerance to sterilizers in relation to the persistence of this bacterium, all of which have been previously associated with this phenotype. Despite much research being published around the topic of persistence, more insights are required to further elucidate the nature of true persistence and its implications for public health. View Full-Text
Keywords: Listeria monocytogenes; virulence; persistence; whole genome sequencing; genotypes; biocide resistance; taxonomy Listeria monocytogenes; virulence; persistence; whole genome sequencing; genotypes; biocide resistance; taxonomy
Show Figures

Figure 1

MDPI and ACS Style

Unrath, N.; McCabe, E.; Macori, G.; Fanning, S. Application of Whole Genome Sequencing to Aid in Deciphering the Persistence Potential of Listeria monocytogenes in Food Production Environments. Microorganisms 2021, 9, 1856. https://doi.org/10.3390/microorganisms9091856

AMA Style

Unrath N, McCabe E, Macori G, Fanning S. Application of Whole Genome Sequencing to Aid in Deciphering the Persistence Potential of Listeria monocytogenes in Food Production Environments. Microorganisms. 2021; 9(9):1856. https://doi.org/10.3390/microorganisms9091856

Chicago/Turabian Style

Unrath, Natalia, Evonne McCabe, Guerrino Macori, and Séamus Fanning. 2021. "Application of Whole Genome Sequencing to Aid in Deciphering the Persistence Potential of Listeria monocytogenes in Food Production Environments" Microorganisms 9, no. 9: 1856. https://doi.org/10.3390/microorganisms9091856

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop