Antimicrobial Prosthetic Surfaces in the Oral Cavity—A Perspective on Creative Approaches
Abstract
:1. Introduction
2. Elements in Bioactive Coatings
3. Antiseptics and Disinfectants in Bioactive Coatings
4. Antibiotics in Bioactive Coatings
5. AMPs in Bioactive Coatings
6. Antimicrobial Substances with Future Potential in Bioactive Coatings
7. Future Directions
Author Contributions
Funding
Conflicts of Interest
References
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Element | Modified Material | Antimicrobial Activity | Pathogen(s) | References |
---|---|---|---|---|
Silver (Ag) | Ag nanoparticle–TiO2 composite | Growth inhibition | Methicillin-resistant Staphylococcus aureus (MRSA) | [24,25,26] |
Ag nanoparticle–polyacrylate hydrogel | Growth inhibition | Gram-positive, Gram-negative bacteria | [27] | |
Ag nanoparticles, chitosan | Growth inhibition | Staphylococcus aureus, Pseudomonas aeruginosa | [28] | |
Ag nanoparticles | 16.3–52.5% inhibition | Candidaalbicans | [29] | |
Ag nanoparticles (20.0–30.0%) | Growth inhibition | C. albicans | [30] | |
Ag benzoate (0.2 and 0.5%) | 52.4–97.5% inhibition | Streptococcus mutans | [31] | |
Ag nitrate (0.5 and 25.0 µg/mL) | Growth inhibition | S. mutans, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola, Tannerella forsythia, Fusobacterium nucleatum ss vincentii, Campylobacter gracilis, Campylobacter rectus, Eikenella corrodens, Aggregatibacter actinomycetemcomitans | [22] | |
Gold (Au) | Au nanoparticles, cefaclor | Growth inhibition | S. aureus, Escherichia coli | [32] |
Cobalt (Co) | Co in resin | Growth inhibition | S. aureus, E. coli | [23] |
Copper (Cu) | Cu oxide nanocomposites, polyurethane | Growth inhibition | MRSA | [33] |
Cu in diamond-like carbon film | Growth inhibition | S. aureus, E. coli | [34] | |
Cu in resin | Growth inhibition | S. aureus, E. coli | [23] | |
Zinc (Zn) | ZnO coating | Growth inhibition | S. aureus, E. coli | [35] |
Zn in resin | Growth inhibition | S. aureus, E. coli | [23] | |
Zirconium (Zr) | Zr in resin | Growth inhibition | S. aureus, E. coli | [23] |
Bismuth (Bi) | BiN3O9, C6H9BiO6 coating | Growth inhibition | A. actinomycetemcomitans, MRSA | [36] |
Selenium (Se) | Se in hydroxyapatite coating | Growth inhibition | P. aeruginosa, S. aureus biofilms | [37] |
Molybdenum (Mo) | Mo in resin | Growth inhibition | S. aureus, E. coli | [23] |
Lead (Pb) | Pb in resin | Growth inhibition | S. aureus, E. coli | [23] |
Antiseptic, Disinfectant | Material | Antimicrobial Activity | Pathogen | References |
---|---|---|---|---|
Poly-(4-vinyl-N-hexyl pyridiniumbromide) | Coating | No inhibition | Streptococcus mutans, Streptococcussanguinis | [44] |
Chlorhexidine (CHX) | 0.02% CHX digluconate, chitosan coating | 95–100% inhibition | Staphylococcus epidermidis | [45] |
0.02% CHX digluconate, chitosan coating | 0–56% inhibition | Aggregatibacteractinomycetemcomitans | [45] | |
1.0% CHX digluconate polymer-based coating | 98% inhibition | Candida albicans biofilm | [46] | |
Fluoridated hydroxyapatite | Fluoridated calcium phosphate coating | 51.6–82.3% inhibition | Staphylococcus aureus, Escherichia coli, Porphyromonasgingivalis | [47] |
Polyhexanide | Hyaluronic acid, polyhexanide nanocapsules | 62.5–250.0 µg/mL MIC | S. aureus, E. coli | [43] |
Guanidine | 2-aminoethyl-methacrylate polymer | 16 µg/mL MIC | E. coli, Bacillus subtilis | [42] |
Antibiotic | Material | Antimicrobial Activity | Pathogen | References |
---|---|---|---|---|
Cefaclor (CEC) | Gold (Au) nanoparticles, cefaclor | Growth inhibition | Staphylococcus aureus, Escherichia coli | [32] |
Cefalotin (CET) | CET, apatite | Growth inhibition | Streptococcus mutans | [51] |
Tobramycin (TOB) | TOB, octacalcium phosphate layer | Growth inhibition | Pseudomonas aeruginosa | [52] |
Vancomycin (VAN) | VAN, chitosan | Growth inhibition | S. aureus | [49] |
VAN, polymer films | Growth inhibition | S. aureus | [50] | |
Gentamicin (GEN) | GEN, poly(d,l-lactide) coating | Growth inhibition | S. aureus | [53] |
Tetracycline (TET) | 20.0% TET, chitosan coating | 94–99% inhibition | Staphylococcus epidermidis, Aggregatibacteractinomycetemcomitans | [45] |
Nystatin (NYT) | 1.0% NYT, polymer coating | 74–75% inhibition | Candida albicans biofilm | [46] |
Amphotericin B (AMB) | 0.1% AMB, polymer coating | 49–55% inhibition | C. albicans biofilm | [46] |
Antimicrobial Peptide | Material | Antimicrobial Activity | Pathogen | References |
---|---|---|---|---|
Tet213 | Tet213, octacalcium phosphate layer | Growth inhibition | Pseudomonas aeruginosa | [52] |
Mx226 | Mx226, octacalcium phosphate layer | Growth inhibition | P. aeruginosa | [52] |
human lactoferrin 1-11 (hLF1-11) | hLF1-11, octacalcium phosphate layer | Growth inhibition | P. aeruginosa | [52] |
HHC36 | HHC36, octacalcium phosphate layer | Growth inhibition | P. aeruginosa and Staphylococcus aureus | [52] |
Carboxy-terminal leucine/isoleucine heptad repeat-1,3 (Chr-1,3) | Chr-1, 3 in acrylate 50% w/w resin | Growth inhibition | S. aureus, Escherichia coli | [67] |
Human β defensin 2 (HBD2) | HBD2, methoxy silane | 60–100% inhibition | E. coli | [59] |
Ponericin (G1) | Ponericin G1 in multilayer films | Growth inhibition | S. aureus | [68] |
Cathelicidin (LL-37) | LL-37 surface peptide layer | Growth inhibition | Bacteria | [58] |
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Garaicoa, J.L.; Bates, A.M.; Avila-Ortiz, G.; Brogden, K.A. Antimicrobial Prosthetic Surfaces in the Oral Cavity—A Perspective on Creative Approaches. Microorganisms 2020, 8, 1247. https://doi.org/10.3390/microorganisms8081247
Garaicoa JL, Bates AM, Avila-Ortiz G, Brogden KA. Antimicrobial Prosthetic Surfaces in the Oral Cavity—A Perspective on Creative Approaches. Microorganisms. 2020; 8(8):1247. https://doi.org/10.3390/microorganisms8081247
Chicago/Turabian StyleGaraicoa, Jorge L., Amber M. Bates, Gustavo Avila-Ortiz, and Kim A. Brogden. 2020. "Antimicrobial Prosthetic Surfaces in the Oral Cavity—A Perspective on Creative Approaches" Microorganisms 8, no. 8: 1247. https://doi.org/10.3390/microorganisms8081247