HHV-6A Infection and Systemic Sclerosis: Clues of a Possible Association
- Supplementary File 1:
ZIP-Document (ZIP, 453 KiB)
Externally hosted supplementary file 1
Description: Suppl. Figure 1. Induction of fibrosis-associated factors by HHV-6A/B infection in human endothelial cells (HUVEC). The modulation of factors potentially associated with fibrosis development was assayed in uninfected HUVEC (CTR) or in HUVEC infected in vitro with HHV-6A, HHV-6B, or the respective UV-inactivated viruses, used as controls. Total RNA was extracted 48 hours post-infection and analyzed by a microarray quantifying simultaneously 84 factors associated with fibrosis. Results are expressed as mean values of duplicate samples in three independent experiments ± SD of fold-change compared to values detected in controls (CTR), after normalization for six housekeeping genes (β-actin, β2-microglobulin, GAPDH, HPRT1, RPLP0, and HGDC).
Caselli, E.; Soffritti, I.; D’Accolti, M.; Bortolotti, D.; Rizzo, R.; Sighinolfi, G.; Giuggioli, D.; Ferri, C. HHV-6A Infection and Systemic Sclerosis: Clues of a Possible Association. Microorganisms 2020, 8, 39. https://doi.org/10.3390/microorganisms8010039
Caselli E, Soffritti I, D’Accolti M, Bortolotti D, Rizzo R, Sighinolfi G, Giuggioli D, Ferri C. HHV-6A Infection and Systemic Sclerosis: Clues of a Possible Association. Microorganisms. 2020; 8(1):39. https://doi.org/10.3390/microorganisms8010039Chicago/Turabian Style
Caselli, Elisabetta, Irene Soffritti, Maria D’Accolti, Daria Bortolotti, Roberta Rizzo, Gianluca Sighinolfi, Dilia Giuggioli, and Clodoveo Ferri. 2020. "HHV-6A Infection and Systemic Sclerosis: Clues of a Possible Association" Microorganisms 8, no. 1: 39. https://doi.org/10.3390/microorganisms8010039