Trends from the Last Decade with Nontuberculous Mycobacteria Lung Disease (NTM-LD): Clinicians’ Perspectives in Regional Center of Pulmonology in Bydgoszcz, Poland
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Subjects
2.2. Laboratory Procedures
3. Results
3.1. Microbiological Examination
3.2. Clinical and Radiological Significance
3.3. Trends
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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NTM Species | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|---|---|---|---|---|---|---|
M. abscessus | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2 |
M. avium | 9 | 4 | 9 | 9 | 18 | 17 | 10 | 12 | 11 | 18 | 117 |
M. chelonae | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3 |
M. chimaera | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 2 | 4 | 9 |
M. fortuitum | 2 | 3 | 2 | 1 | 0 | 1 | 0 | 0 | 2 | 0 | 11 |
M. gordonae | 8 | 11 | 2 | 1 | 5 | 4 | 3 | 1 | 1 | 3 | 39 |
M. interjectum | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
M. intracellulare | 4 | 1 | 0 | 4 | 0 | 5 | 1 | 2 | 2 | 3 | 22 |
M. kansasii | 14 | 11 | 17 | 15 | 18 | 20 | 17 | 8 | 5 | 9 | 134 |
M. lentiflavum | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
M. mageritense | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
M. malmoense | 0 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 7 |
M. neoaurum | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
M. nonchromogenicum | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
M. peregrinum | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 3 |
M. szulgai | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3 |
M. xenopi | 5 | 2 | 1 | 1 | 2 | 2 | 3 | 3 | 2 | 0 | 21 |
other RGM | 3 | 1 | 1 | 1 | 2 | 4 | 0 | 4 | 1 | 0 | 17 |
Total | 47 | 38 | 36 | 34 | 47 | 57 | 37 | 33 | 27 | 39 | 395 |
NTM Species | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|---|---|---|---|---|---|---|
M. kansasii | 9 | 10 | 8 | 9 | 12 | 12 | 10 | 4 | 3 | 0 | 77 |
MAC | 0 | 4 | 0 | 5 | 7 | 9 | 9 | 3 | 5 | 4 | 46 |
M. xenopi | 4 | 1 | 1 | 0 | 1 | 0 | 1 | 3 | 2 | 0 | 13 |
M. malmoense | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 5 |
M. gordonae | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 |
M. szulgai | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 |
M. abscessus | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
M. fortuitum | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
M. interjectum | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Total | 16 | 17 | 10 | 15 | 20 | 22 | 21 | 11 | 11 | 6 | 149 |
Underlying Condition | n | (%) |
---|---|---|
Lung disease | 41 | (27.5) |
Cancer | 10 | (6.7) |
Diabetes | 11 | (7.4) |
Immunodeficiency: | ||
Hematological malignancies | 3 | (2.0) |
Biological treatment | 2 | (1.3) |
HIV | 2 | (1.3) |
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Przybylski, G.; Bukowski, J.; Kowalska, W.; Pilaczyńska-Cemel, M.; Krawiecka, D. Trends from the Last Decade with Nontuberculous Mycobacteria Lung Disease (NTM-LD): Clinicians’ Perspectives in Regional Center of Pulmonology in Bydgoszcz, Poland. Pathogens 2023, 12, 988. https://doi.org/10.3390/pathogens12080988
Przybylski G, Bukowski J, Kowalska W, Pilaczyńska-Cemel M, Krawiecka D. Trends from the Last Decade with Nontuberculous Mycobacteria Lung Disease (NTM-LD): Clinicians’ Perspectives in Regional Center of Pulmonology in Bydgoszcz, Poland. Pathogens. 2023; 12(8):988. https://doi.org/10.3390/pathogens12080988
Chicago/Turabian StylePrzybylski, Grzegorz, Jakub Bukowski, Weronika Kowalska, Marta Pilaczyńska-Cemel, and Dorota Krawiecka. 2023. "Trends from the Last Decade with Nontuberculous Mycobacteria Lung Disease (NTM-LD): Clinicians’ Perspectives in Regional Center of Pulmonology in Bydgoszcz, Poland" Pathogens 12, no. 8: 988. https://doi.org/10.3390/pathogens12080988