Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology
Abstract
:1. Introduction
2. Immunotherapy against Cancer
3. Transposable Elements
3.1. Retrotransposons
3.1.1. Non-LTR Retrotransposons
3.1.2. LTR Retrotransposons
4. Endogenous dsRNA Production and Sensing
5. ADAR1 and the Fine Tuning of dsRNA Sensing
6. Epigenetic Regulation of Retroelements
6.1. DNA Methyltransferases Inhibitors
6.2. LSD1 Inhibitors
6.3. EZH2 Inhibitors
6.4. HDAC Inhibitors
6.5. G9A Inhibitors
7. Perspectives
Funding
Conflicts of Interest
References
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Barrero, M.J. Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology. Epigenomes 2020, 4, 22. https://doi.org/10.3390/epigenomes4030022
Barrero MJ. Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology. Epigenomes. 2020; 4(3):22. https://doi.org/10.3390/epigenomes4030022
Chicago/Turabian StyleBarrero, Maria J. 2020. "Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology" Epigenomes 4, no. 3: 22. https://doi.org/10.3390/epigenomes4030022