Insects 2013, 4(4), 593-608; doi:10.3390/insects4040593
Article

Exploring the Role of Rhodtestolin, A Cardio-Inhibitor from the Testes of Rhodnius prolixus, in Relation to the Structure and Function of Reproductive Organs in Insect Vectors of Chagas Disease

1 Biology Department, Redeemer University College, Ancaster, Ontario, L9K 1J4, Canada 2 Affinity Biologicals Inc., Ancaster, Ontario, L9G 4V5, Canada 3 Laboratorio de Ecoepidemiologia da Doenca de Chagas, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, RJ, Brazil
* Author to whom correspondence should be addressed.
Received: 31 August 2013; in revised form: 8 October 2013 / Accepted: 21 October 2013 / Published: 30 October 2013
(This article belongs to the Special Issue Feature Papers 2013)
PDF Full-text Download PDF Full-Text [846 KB, uploaded 30 October 2013 14:43 CET]
Abstract: Rhodtestolin is a cardio-inhibitor that was first discovered in testes extracts of the blood-feeding insect, Rhodnius prolixus. Its role in reproduction remains unconfirmed, but if delivered to the female during spermatophore formation, it may serve to calm the female and/or relax the vaginal muscles to facilitate delivery and storage of the spermatophore. We describe here the anatomy of reproductive organs in R. prolixus and show that rhodtestolin is present in a low-molecular weight fraction of testes extracts separated by gel filtration, as well as in spermatophores delivered to the female during spermatophore formation. We also report that a rhodtestolin-like factor is present in the testes of R. brethesi, Triatoma dimidiata, T. klugi and Nesotriatoma bruneri, other Reduviidae, which are vectors of Chagas disease. Male secretions in insects are known to modify female behavior after copulation, and the presence of rhodtestolin in several genera of Reduviidae suggests that it plays an important role in reproductive success. Determining this role could lead to developing additional population control strategies for these bugs.
Keywords: Reduviidae; Triatominae; Rhodnius; cardio-inhibitor; rhodtestolin; testes extracts; spermatophore; insect reproduction; Chagas disease

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Chiang, R.G.; Chiang, J.A.; Hoogendoorn, H.; Lima, M.M. Exploring the Role of Rhodtestolin, A Cardio-Inhibitor from the Testes of Rhodnius prolixus, in Relation to the Structure and Function of Reproductive Organs in Insect Vectors of Chagas Disease. Insects 2013, 4, 593-608.

AMA Style

Chiang RG, Chiang JA, Hoogendoorn H, Lima MM. Exploring the Role of Rhodtestolin, A Cardio-Inhibitor from the Testes of Rhodnius prolixus, in Relation to the Structure and Function of Reproductive Organs in Insect Vectors of Chagas Disease. Insects. 2013; 4(4):593-608.

Chicago/Turabian Style

Chiang, Ralem G.; Chiang, Jennifer A.; Hoogendoorn, Hugh; Lima, Marli M. 2013. "Exploring the Role of Rhodtestolin, A Cardio-Inhibitor from the Testes of Rhodnius prolixus, in Relation to the Structure and Function of Reproductive Organs in Insect Vectors of Chagas Disease." Insects 4, no. 4: 593-608.

Insects EISSN 2075-4450 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert