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Article

Improvement of Fatigue and Body Composition in Women with Long COVID After Non-Aerobic Therapeutic Exercise Program

by
María Miana
1,
Ricardo Moreta-Fuentes
2,
Carmen Jiménez-Antona
3,*,
César Moreta-Fuentes
4 and
Sofía Laguarta-Val
3
1
Faculty of Nursing and Physiotherapy Salus Infirmorum, Pontifical University of Salamanca, 28015 Madrid, Spain
2
Fisyos Center, Método Moreta, 28027 Madrid, Spain
3
Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Faculty of Health Sciences, Universidad Rey Juan Carlos (URJC), 28922 Alcorcón, Madrid, Spain
4
FREMAP Care Center, 28946 Fuenlabrada, Madrid, Spain
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2025, 15(6), 217; https://doi.org/10.3390/jpm15060217
Submission received: 11 April 2025 / Revised: 16 May 2025 / Accepted: 20 May 2025 / Published: 26 May 2025

Abstract

Background/Objective: Fatigue is one of the most recurrent and most disabling symptoms of long COVID (LC) and is associated with a worse quality of life. Reducing body fat in these patients could be important to mitigate fatigue and post-exertional worsening. Aerobic exercise may not be indicated in LC patients who have orthostatic tachycardia and post-exertional worsening. The aim of this study was to evaluate the effects of a personalized supine therapeutic motor control exercise program on fatigue and fat tissue in women with LC. Methods: A single-arm exploratory case study, with a pre–post format, was conducted on 17 women with LC to test the effects of a plank-based strengthening exercise program on fatigue, which was evaluated by the Modified Fatigue Impact Scale and fat tissue assessed by bioimpedance. The twelve-week program included two weekly sessions. The exercise program was personalized, considering the symptoms and characteristics of the patients. Results: Participants with overweight or obesity (n = 12) comprised 70% of the entire sample. After completing the exercise program this value decreased by 5.9 percentage points. Significant differences were found in the total [(MD  = −1.72, 95% CI −2.57 to −0.86), r = 0.73], trunk, upper and inner limbs body fat percentages (p < 0.05). The overall fatigue decreased at 12 weeks [(MD  =  −14.00, 95% CI −21.69 to −6.31), r = 0.69] as well as the physical and psychosocial fatigue sub-scale (p  <  0.001); no differences were observed in the cognitive sub-scale. Conclusions: The plank-based personalized strengthening exercise program showed rapid improvements in fatigue and fat percentages. It could be an effective strategy to achieve improvements for LC patients.
Keywords: body fat distribution; exercise therapy; fatigue; post-acute COVID-19 syndrome body fat distribution; exercise therapy; fatigue; post-acute COVID-19 syndrome
Graphical Abstract

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MDPI and ACS Style

Miana, M.; Moreta-Fuentes, R.; Jiménez-Antona, C.; Moreta-Fuentes, C.; Laguarta-Val, S. Improvement of Fatigue and Body Composition in Women with Long COVID After Non-Aerobic Therapeutic Exercise Program. J. Pers. Med. 2025, 15, 217. https://doi.org/10.3390/jpm15060217

AMA Style

Miana M, Moreta-Fuentes R, Jiménez-Antona C, Moreta-Fuentes C, Laguarta-Val S. Improvement of Fatigue and Body Composition in Women with Long COVID After Non-Aerobic Therapeutic Exercise Program. Journal of Personalized Medicine. 2025; 15(6):217. https://doi.org/10.3390/jpm15060217

Chicago/Turabian Style

Miana, María, Ricardo Moreta-Fuentes, Carmen Jiménez-Antona, César Moreta-Fuentes, and Sofía Laguarta-Val. 2025. "Improvement of Fatigue and Body Composition in Women with Long COVID After Non-Aerobic Therapeutic Exercise Program" Journal of Personalized Medicine 15, no. 6: 217. https://doi.org/10.3390/jpm15060217

APA Style

Miana, M., Moreta-Fuentes, R., Jiménez-Antona, C., Moreta-Fuentes, C., & Laguarta-Val, S. (2025). Improvement of Fatigue and Body Composition in Women with Long COVID After Non-Aerobic Therapeutic Exercise Program. Journal of Personalized Medicine, 15(6), 217. https://doi.org/10.3390/jpm15060217

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