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Review

Contemporary Management of Severely Calcified Coronary Lesions

by
Natthapon Angsubhakorn
1,
Nicolas Kang
2,
Colleen Fearon
1,
Chol Techorueangwiwat
3,
Pooja Swamy
1,
Emmanouil S. Brilakis
4 and
Aditya S. Bharadwaj
1,*
1
Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
2
Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
3
Division of Cardiology, University of California, Riverside, CA 92521, USA
4
Minneapolis Heart Institute, Abbott Northwestern Hospital and Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2022, 12(10), 1638; https://doi.org/10.3390/jpm12101638
Submission received: 31 August 2022 / Revised: 26 September 2022 / Accepted: 29 September 2022 / Published: 3 October 2022
(This article belongs to the Special Issue Novel Challenges and Advances in Complex Coronary Interventions)

Abstract

Coronary artery calcification is increasingly prevalent in our patient population. It significantly limits the procedural success of percutaneous coronary intervention and is associated with a higher risk of adverse cardiovascular events both in the short-term and long-term. There are several modalities for modifying calcified plaque, such as balloon angioplasty (including specialty balloons), coronary atheroablative therapy (rotational, orbital, and laser atherectomy), and intravascular lithotripsy. We discuss each modality’s relative advantages and disadvantages and the data supporting their use. This review also highlights the importance of intravascular imaging to characterize coronary calcification and presents an algorithm to tailor the calcium modification therapy based on specific coronary lesion characteristics.
Keywords: coronary artery calcification; intravascular imaging; percutaneous coronary intervention coronary artery calcification; intravascular imaging; percutaneous coronary intervention

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MDPI and ACS Style

Angsubhakorn, N.; Kang, N.; Fearon, C.; Techorueangwiwat, C.; Swamy, P.; Brilakis, E.S.; Bharadwaj, A.S. Contemporary Management of Severely Calcified Coronary Lesions. J. Pers. Med. 2022, 12, 1638. https://doi.org/10.3390/jpm12101638

AMA Style

Angsubhakorn N, Kang N, Fearon C, Techorueangwiwat C, Swamy P, Brilakis ES, Bharadwaj AS. Contemporary Management of Severely Calcified Coronary Lesions. Journal of Personalized Medicine. 2022; 12(10):1638. https://doi.org/10.3390/jpm12101638

Chicago/Turabian Style

Angsubhakorn, Natthapon, Nicolas Kang, Colleen Fearon, Chol Techorueangwiwat, Pooja Swamy, Emmanouil S. Brilakis, and Aditya S. Bharadwaj. 2022. "Contemporary Management of Severely Calcified Coronary Lesions" Journal of Personalized Medicine 12, no. 10: 1638. https://doi.org/10.3390/jpm12101638

APA Style

Angsubhakorn, N., Kang, N., Fearon, C., Techorueangwiwat, C., Swamy, P., Brilakis, E. S., & Bharadwaj, A. S. (2022). Contemporary Management of Severely Calcified Coronary Lesions. Journal of Personalized Medicine, 12(10), 1638. https://doi.org/10.3390/jpm12101638

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